Search Results - "Goldfarb, Inna"
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Monoclonal Antibodies Specific and Inhibitory to Human Cytochromes P450 2C8, 2C9, and 2C19
Published in Drug metabolism and disposition (01-11-2001)“…Hybridomas were isolated that produce 13 monoclonal antibodies (mAbs) that are specific and highly inhibitory to members of the human P450 2C subfamily, 2C8,…”
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Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4
Published in Biochemical pharmacology (27-11-1995)“…Cytochromes P450 3A3/4 are inordinately important P450 enzymes catalyzing the metabolism of a large variety of clinically useful drugs, steroids, and…”
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Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene
Published in Molecular carcinogenesis (01-12-1996)“…7,12‐Dimethylbenz[a]anthracene (DMBA), a potent carcinogen, requires metabolic activation by cytochrome P450s (P450s) to electrophilic metabolites that result…”
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Inhibitory and Noninhibitory Monoclonal Antibodies to Human Cytochrome P450 2E1
Published in Chemical research in toxicology (1996)“…A panel of 17 hybridomas producing (MAbs) against human cytochrome P450 2E1 (h2E1) was generated by immunizing mice with baculovirus-expressed h2E1. All 17…”
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Clonal analysis of a human antibody response: quantitation of precursors of antibody-producing cells and generation on characterization of monoclonal IgM, IgG, and IgA to rabies virus
Published in The Journal of experimental medicine (1990)“…We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we…”
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Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2
Published in Archives of biochemistry and biophysics (01-12-1993)“…Kinetics of benzo[alpha]pyrene hydroxylase (AHH), 7-methoxyresorufin o-demethylase (MROD), and 7-ethoxyresorufin o-deethylase (EROD) were estimated in…”
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Monoclonal antibodies to cytochromes P450
Published in Methods in molecular biology (Clifton, N.J.) (1998)Get more information
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Cross-reactivity of thirteen monoclonal antibodies with ten vaccinia cDNA expressed rat, mouse and human cytochrome P450s
Published in Biochemical pharmacology (01-09-1993)“…Twelve monoclonal antibodies (MAbs) to rat cytochrome P450s and one MAb to a scup (fish) P450 have been isolated, characterized, and are currently in common…”
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Model for studying virus attachment. II. Binding of biotinylated human T cell leukemia virus type I to human blood mononuclear cells potential targets for human T cell leukemia virus type I infection
Published in The Journal of immunology (1950) (01-07-1991)“…Purified human T cell leukemia virus type I (HTLV-I) was biotinylated and used to study its attachment to human PBMC. The use of biotinylated HTLV-I…”
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