Search Results - "Goldfarb, Christine"
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Interplay Between GH-regulated, Sex-biased Liver Transcriptome and Hepatic Zonation Revealed by Single-Nucleus RNA Sequencing
Published in Endocrinology (Philadelphia) (01-07-2022)“…The zonation of liver metabolic processes is well-characterized; however, little is known about the cell type-specificity and zonation of sexually dimorphic…”
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Journal Article -
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Global analysis of expression, maturation and subcellular localization of mouse liver transcriptome identifies novel sex-biased and TCPOBOP-responsive long non-coding RNAs
Published in BMC genomics (24-03-2021)“…While nuclear transcription and RNA processing and localization are well established for protein coding genes (PCGs), these processes are poorly understood for…”
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Journal Article -
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Glioma progression is shaped by genetic evolution and microenvironment interactions
Published in Cell (09-06-2022)“…The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed…”
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Journal Article -
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Sex-Biased and Xenobiotic-Responsive Long Non-Coding RNAs in Mouse Liver: Sub-Cellular Localization, Liver Cell-Type Specificity, and Knockdown by Epigenetic Reprogramming
Published 01-01-2021“…Long non-coding RNAs (lncRNAs) are key regulators of gene expression, playing crucial roles in biological processes across many species, tissues and diseases…”
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Dissertation