Search Results - "Goldenthal, M"

Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure by Marín-García, J, Goldenthal, M J, Moe, G W

“…Previous studies have shown that marked changes in myocardial mitochondrial structure and function occur in human cardiac failure. To further understand the…”
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Mitochondrial pathology in cardiac failure by MARIN-GARCIA, Jose, GOLDENTHAL, Michael J, MOE, Gordon W

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Nuclear-mitochondrial cross-talk in cardiomyocyte T3 signaling: A time-course analysis by Goldenthal, Michael J., Ananthakrishnan, Radha, Marín-García, José

“…Thyroid hormone (TH) induces marked changes in the biochemical and physiological functioning of cardiac muscle affecting its bioenergetics, contractility and…”
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Biochemical and molecular basis for mitochondrial cardiomyopathy in neonates and children by Marin‐Garcia, J., Ananthakrishnan, R., Goldenthal, M. J., Pierpont, M. E.

“…Defects in myocardial bioenergetics have been reported in patients with cardiomyopathy but their molecular basis and role in pathophysiology remain unclear. We…”
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Mitochondrial cardiomyopathy: molecular and biochemical analysis by Marin-Garcia, J, Goldenthal, M J

“…Abnormalities in cardiac mitochondrial respiratory enzymes and mitochondrial DNA have been found in an increasing number of pediatric cases of both dilated and…”
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Mitochondrial biogenesis defects and neuromuscular disorders by Marin-Garcia, Jose, Goldenthal, Michael J

“…A variety of mitochondrial DNA (mtDNA) defects, ranging from point mutations and large-scale deletions to severe reduction in the overall quantity of mtDNA…”
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Mitochondrial Dysfunction in Skeletal Muscle of Children With Cardiomyopathy by Marin-Garcia, Jose, Ananthakrishnan, Radha, Goldenthal, Michael J, Filiano, James J, Perez-Atayde, Antonio

“…This study sought to examine skeletal muscle of children with cardiomyopathy (CM) for changes in mitochondrial enzyme activities and in mitochondrial DNA…”
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Specific mitochondrial DNA deletions in idiopathic dilated cardiomyopathy by MARIN-GARCIA, J, GOLDENTHAL, M. J, ANANTHAKRISHNAN, R, PIERPONT, M. E. M, FRICKER, F. J, LIPSHULTZ, S. E, PEREZ-ATAYDE, A

“…Structural changes in human mitochondrial DNA (mtDNA) have been implicated in a number of clinical conditions with dysfunctions in oxidative phosphorylation…”
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Cardiac mitochondrial dysfunction and DNA depletion in children with hypertrophic cardiomyopathy by Marin‐Garcia, J., Ananthakrishnan, R., Goldenthal, M. J., Filiano, J. J., Perez‐Atayde, A.

“…Abnormalities in specific mitochondrial respiratory enzymes and DNA (mtDNA) have been reported in cardiomyopathy. In this study, we report 4 cases of severe…”
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Kearns-Sayre Syndrome With a Novel Mitochondrial DNA Deletion by Marin-Garcia, Jose, Goldenthal, Michael J., Sarnat, Harvey B.

“…We describe a 17-year-old boy with a clinical neurologic picture consistent with Kearns-Sayre syndrome. His manifestations included progressive external…”
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Heart mitochondria response to alcohol is different than brain and liver by Marin-Garcia, J, Ananthakrishnan, R, Goldenthal, M J

“…Specific mitochondrial enzyme activities, mitochondrial DNA copy number, and mRNA levels were measured in heart, brain, and liver tissues of a group of…”
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Cardiomyopathy and abnormal mitochondrial function by Marin-Garcia, J, Goldenthal, M J

“…The diagnosis of cardiomyopathy is mainly based on clinical and morphological criteria. While metabolic, viral, chemical, genetic, and immunological factors…”
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Skeletal muscle mitochondrial defects in nonspecific neurologic disorders by Marin-Garcia, Jose, Ananthakrishnan, Radha, Goldenthal, Michael J, Filiano, James J, Sarnat, Harvey B

“…A group of 25 children (5 months to 20 years of age) presenting with intractable seizures, developmental delay, and severe hypotonia, who did not fall into the…”
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Heart mitochondrial DNA and enzyme changes during early human development by Marin-Garcia, J, Ananthakrishnan, R, Goldenthal, M J

“…Previous studies in our laboratory demonstrated significant changes in bovine heart mitochondrial bioenergetics during fetal growth and development. To further…”
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Mitochondrial function in children with idiopathic dilated cardiomyopathy by Marin‐Garcia, J., Goldenthal, M. J., Ananthakrishnan, R., Pierpont, M. E. M., Fricker, F. J., Lipshultz, S. E., Perez‐Atayde, A.

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Stem cells and cardiac disorders: an appraisal by GOLDENTHAL, Michael J, MARIN-GARCIA, José

“…The use of stem cells has proved to be an important tool in investigating the events of early cardiac development, differentiation, and morphogenesis. In…”
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Mitochondrial dysfunction after fetal alcohol exposure by Marin-Garcia, J, Ananthakrishnan, R, Goldenthal, M J

“…Specific mitochondrial enzyme activities and mRNA levels were measured in the heart, brain, and liver tissues of a group of 1-day-old neonatal rats whose…”
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Novel mutations in mitochondrial cytochrome b in fatal post partum cardiomyopathy by MARIN-GARCIA, J, ANANTHAKRISHNAN, R, GONZALVO, A, GOLDENTHAL, M. J

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Hypertrophic cardiomyopathy with mitochondrial DNA depletion and respiratory enzyme defects by Marin-Garcia, J, Ananthakrishnan, R, Goldenthal, M J

“…We report the case of a child with severe hypertrophic cardiomyopathy, with decreased activity levels of cardiac mitochondrial respiratory complex I and III,…”
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The complete sequence of mtDNA genes in idiopathic dilated cardiomyopathy shows novel missense and tRNA mutations by Marin-Garcia, Jose, Goldenthal, Michael J., Ananthakrishnan, Radha, Pierpont, Mary Ella

“…Background: Previous studies have shown that mitochondrial DNA (mtDNA) mutations are often present in patients with myocardial dysfunction. We sought to assess…”
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