Search Results - "Goldberger, O."
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Modulation of allergic responses by mitochondrial STAT3 inhibitors
Published in Allergy (Copenhagen) (01-11-2018)“…Background Recently, we have shown that mast cell mitochondrial STAT3 could serve as a new target for the regulation of the allergic response as it plays an…”
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Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns
Published in Molecular biology of the cell (01-07-1994)“…The syndecans are a gene family of four transmembrane heparan sulfate proteoglycans that bind, via their HS chains, diverse components of the cellular…”
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Organization and promoter activity of the mouse syndecan-1 gene
Published in The Journal of biological chemistry (25-05-1993)“…Syndecan-1, the prototype of a family of heparan sulfate-containing integral membrane proteoglycans, associates extracellularly with a variety of matrix…”
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Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control binding of midkine, pleiotrophin, and basic fibroblast growth factor
Published in The Journal of biological chemistry (03-09-2004)“…A comparative analysis was carried out of heparan sulfate (HS) and chondroitin sulfate (CS) chains of the ectodomains of hybrid type transmembrane…”
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Mapping of the syndecan genes in the mouse: linkage with members of the myc gene family
Published in Genomics (San Diego, Calif.) (01-06-1994)“…The syndecans are a family of four cell surface heparan sulfate proteoglycans in vertebrates that mediate a variety of cell behaviors, including cell adhesion…”
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Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse
Published in Journal of cell science (01-12-2002)“…Mice lacking syndecan-1 are viable, fertile and have morphologically normal skin, hair and ocular surface epithelia. While studying the response of these mice…”
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Combined Dendritic Cell Cryotherapy of Tumor Induces Systemic Antimetastatic Immunity
Published in Clinical cancer research (01-07-2005)“…Purpose: Cryotherapy of localized prostate, renal, and hepatic primary tumors and metastases is considered a minimally invasive treatment demonstrating a low…”
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Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3
Published in Cell (13-07-2001)“…Transgenic expression in the hypothalamus of syndecan-1, a cell surface heparan sulfate proteoglycan (HSPG) and modulator of ligand-receptor encounters,…”
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Human CTL epitopes prostatic acid phosphatase-3 and six-transmembrane epithelial antigen of prostate-3 as candidates for prostate cancer immunotherapy
Published in Cancer research (Chicago, Ill.) (15-07-2005)“…Specific immunotherapy of prostate cancer may be an alternative or be complementary to other approaches for treatment of recurrent or metastasized disease…”
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Syndecan-1 Shedding Is Enhanced by LasA, a Secreted Virulence Factor of Pseudomonas aeruginosa
Published in The Journal of biological chemistry (04-02-2000)“…Microbial pathogens frequently take advantage of host systems for their pathogenesis. Shedding of cell surface molecules as soluble extracellular domains…”
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Syndecan-1 and -4 Synthesized Simultaneously by Mouse Mammary Gland Epithelial Cells Bear Heparan Sulfate Chains That Are Apparently Structurally Indistinguishable
Published in The Journal of biological chemistry (11-04-2003)“…Many of the biological functions attributed to cell surface heparan sulfate (HS) proteoglycans, including the Syndecan family, are elicited through the…”
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Systematic identification of human mitochondrial disease genes through integrative genomics
Published in Nature genetics (01-05-2006)“…The majority of inherited mitochondrial disorders are due to mutations not in the mitochondrial genome (mtDNA) but rather in the nuclear genes encoding…”
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In vivo rejection of tumor cells dependent on CD8 cells that kill independently of perforin and FasL
Published in Cancer gene therapy (01-03-2004)“…Perforin/granzyme B- and Fas/FasL-mediated killing pathways are the main effector mechanisms of CTL and NK cells in antitumor immune responses. In this study,…”
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Expression of FasL by tumor cells does not abrogate anti-tumor CTL function
Published in Immunology letters (15-02-2004)“…The effects of Fas-ligand (FasL) expression by tumor cells on their tumorigenicity and immunogenicity have been reported as opposite, contradictory results. In…”
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In vivo rejection of tumor cells dependent on CD8 cells that kill independently of perforin and FasL
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