Search Results - "Goldberger, Ary L."
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Heart Rate Fragmentation: A New Approach to the Analysis of Cardiac Interbeat Interval Dynamics
Published in Frontiers in physiology (09-05-2017)“…Short-term heart rate variability (HRV) is most commonly attributed to physiologic vagal tone modulation. However, with aging and cardiovascular disease, the…”
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Scaling Up Scientific Discovery in Sleep Medicine: The National Sleep Research Resource
Published in Sleep (New York, N.Y.) (01-05-2016)“…Professional sleep societies have identified a need for strategic research in multiple areas that may benefit from access to and aggregation of large,…”
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Generalized Multiscale Entropy Analysis: Application to Quantifying the Complex Volatility of Human Heartbeat Time Series
Published in Entropy (Basel, Switzerland) (01-03-2015)“…We introduce a generalization of multiscale entropy (MSE) analysis. The method is termed MSEn, where the subscript denotes the moment used to coarse-grain a…”
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Multiscale entropy analysis of complex physiologic time series
Published in Physical review letters (05-08-2002)“…There has been considerable interest in quantifying the complexity of physiologic time series, such as heart rate. However, traditional algorithms indicate…”
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Therapeutic Ranges of Serum Digoxin Concentrations in Patients With Heart Failure
Published in The American journal of cardiology (15-06-2012)Get full text
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Heart Rate Fragmentation: A Symbolic Dynamical Approach
Published in Frontiers in physiology (14-11-2017)“…We recently introduced the concept of heart rate fragmentation along with a set of metrics for its quantification. The term was coined to refer to an increase…”
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Blood pressure fragmentation as a new measure of blood pressure variability: association with predictors of cardiac surgery outcomes
Published in Frontiers in physiology (2024)“…Fluctuations in beat-to-beat blood pressure variability (BPV) encode untapped information of clinical utility. A need exists for developing new methods to…”
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Prediction of Cognitive Decline Using Heart Rate Fragmentation Analysis: The Multi-Ethnic Study of Atherosclerosis
Published in Frontiers in aging neuroscience (26-08-2021)“…Heart rate fragmentation (HRF), a new non-invasive metric quantifying cardiac neuroautonomic function, is associated with increasing age and cardiovascular…”
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Multiscale entropy analysis of human gait dynamics
Published in Physica A (01-12-2003)“…We compare the complexity of human gait time series from healthy subjects under different conditions. Using the recently developed multiscale entropy…”
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Heart Rate Fragmentation as a Novel Biomarker of Adverse Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis
Published in Frontiers in physiology (03-09-2018)“…A major objective of precision medicine is the elucidation of non-invasive biomarkers of cardiovascular (CV) risk. Recently, we introduced a new dynamical…”
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Relationship between delta power and the electrocardiogram-derived cardiopulmonary spectrogram: possible implications for assessing the effectiveness of sleep
Published in Sleep medicine (01-01-2014)“…Abstract Objectives The physiologic relationship between slow-wave activity (SWA) (0–4 Hz) on the electroencephalogram (EEG) and high-frequency (0.1–0.4 Hz)…”
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Fractal dynamics in physiology: Alterations with disease and aging
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2002)“…According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary…”
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Differentiating Obstructive from Central and Complex Sleep Apnea Using an Automated Electrocardiogram-Based Method
Published in Sleep (New York, N.Y.) (01-12-2007)“…Complex sleep apnea is defined as sleep disordered breathing secondary to simultaneous upper airway obstruction and respiratory control dysfunction. The…”
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Multiscale analysis of heart rate dynamics: entropy and time irreversibility measures
Published in Cardiovascular engineering (Dordrecht, Netherlands) (01-06-2008)“…Cardiovascular signals are largely analyzed using traditional time and frequency domain measures. However, such measures fail to account for important…”
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Heart rate dynamics after combined strength and endurance training in middle-aged women: heterogeneity of responses
Published in PloS one (27-08-2013)“…The loss of complexity in physiological systems may be a dynamical biomarker of aging and disease. In this study the effects of combined strength and endurance…”
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Multifractality in human heartbeat dynamics
Published in Nature (London) (03-06-1999)“…There is evidence that physiological signals under healthy conditions may have a fractal temporal structure. Here we investigate the possibility that time…”
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Effect of Mild, Asymptomatic Obstructive Sleep Apnea on Daytime Heart Rate Variability and Impedance Cardiography Measurements
Published in The American journal of cardiology (01-01-2012)“…Dysregulation of autonomic nervous system dynamics is important in the pathophysiology of cardiovascular risk in obstructive sleep apnea (OSA). Heart rate…”
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Magnitude and sign correlations in heartbeat fluctuations
Published in Physical review letters (26-02-2001)“…We propose an approach for analyzing signals with long-range correlations by decomposing the signal increment series into magnitude and sign series and…”
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Complexity-loss in fetal heart rate dynamics during labor as a potential biomarker of acidemia
Published in Early human development (01-01-2014)“…Abstract Background Continuous fetal heart rate (FHR) monitoring remains central to intrapartum care. However, advances in signal analysis are needed to…”
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Dynamic markers of altered gait rhythm in amyotrophic lateral sclerosis
Published in Journal of applied physiology (1985) (01-06-2000)“…1 Margret and H. A. Rey Laboratory for Nonlinear Dynamics in Medicine and 2 Gerontology Division, Beth Israel Deaconess Medical Center, Boston 02215; 3…”
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