Search Results - "Goldberg, Sarah A"
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Chronic viral coinfections differentially affect the likelihood of developing long COVID
Published in The Journal of clinical investigation (01-02-2023)“…BACKGROUNDThe presence and reactivation of chronic viral infections, such as EBV, CMV, and HIV, have been proposed as potential contributors to long COVID…”
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Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study
Published in PLoS pathogens (01-09-2022)“…The impact of vaccination on SARS-CoV-2 infectiousness is not well understood. We compared longitudinal viral shedding dynamics in unvaccinated and fully…”
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Early biological markers of post-acute sequelae of SARS-CoV-2 infection
Published in Nature communications (29-08-2024)“…To understand the roles of acute-phase viral dynamics and host immune responses in post-acute sequelae of SARS-CoV-2 infection (PASC), we enrolled 136…”
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SARS-CoV-2 antibody prevalence in Sierra Leone, March 2021: a cross-sectional, nationally representative, age-stratified serosurvey
Published in BMJ global health (01-11-2021)“…IntroductionAs of 26 March 2021, the Africa Centres for Disease Control and Prevention had reported 4 159 055 cases of COVID-19 and 111 357 deaths among the 55…”
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Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients
Published in JCI insight (08-06-2023)“…Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as long COVID. The underlying pathophysiology of…”
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SARS‐CoV‐2 and Mitochondrial Proteins in Neural‐Derived Exosomes of COVID‐19
Published in Annals of neurology (01-06-2022)“…Objective As SARS‐CoV‐2 is known to invade neural cell mitochondria, a plasma system for quantifying central nervous system proteins in living humans was used…”
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Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Published in The Journal of infectious diseases (01-12-2021)“…Abstract Background The biological processes associated with postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
Published in Nature (London) (03-08-2023)“…Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic 1 – 4 . Although most global efforts have focused on…”
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Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
Published in Nature immunology (01-02-2024)“…Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly…”
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Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection
Published in AIDS (London) (01-10-2022)“…Limited data are available on the long-term clinical and immunologic consequences of SARS-CoV-2 infection in people with HIV (PWH). We measured…”
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Plasma-based antigen persistence in the post-acute phase of COVID-19
Published in The Lancet infectious diseases (01-06-2024)“…Persistent symptoms among some individuals who develop COVID-19 have led to the hypothesis that SARS-CoV-2 might, in some form or location, persist for long…”
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Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019
Published in The Journal of infectious diseases (31-08-2023)“…Abstract Background Mechanisms underlying persistent cardiopulmonary symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Prevalence, Patterns, and Predictors of SARS-CoV-2 RNA and Culturable Virus in Tears of a Case-Ascertained Household Cohort
Published in American journal of ophthalmology (01-09-2024)“…To investigate the prevalence, patterns, and predictors of SARS-CoV-2 RNA and culturable virus in tears of a case-ascertained household cohort. Prospective,…”
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Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection
Published in Science translational medicine (03-07-2024)“…The mechanisms of postacute medical conditions and unexplained symptoms after SARS-CoV-2 infection [Long Covid (LC)] are incompletely understood. There is…”
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Magnitude and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission: A Longitudinal Cohort Study
Published in Clinical infectious diseases (03-10-2022)“…Abstract Background Households have emerged as important venues for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Little is known,…”
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Association of Culturable-Virus Detection and Household Transmission of SARS-CoV-2, California and Tennessee, 2020-2022
Published in The Journal of infectious diseases (15-06-2023)“…From 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission studies (enrolling April 2020 to January 2022) with rapid enrollment…”
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The breadth of the neutralizing antibody response to original SARS‐CoV‐2 infection is linked to the presence of Long COVID symptoms
Published in Journal of medical virology (01-11-2023)“…The associations between longitudinal dynamics and the breadth of SARS‐CoV‐2 neutralizing antibody (nAb) response with various Long COVID phenotypes before…”
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Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement
Published in Open forum infectious diseases (01-02-2022)“…Abstract Background There is mounting evidence for the presence of postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection
Published in Neurology : neuroimmunology & neuroinflammation (01-09-2022)“…The biologic mechanisms underlying neurologic postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) are…”
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Viral Determinants of Acute COVID-19 Symptoms in a Nonhospitalized Adult Population in the Pre-Omicron Era
Published in Open forum infectious diseases (01-08-2023)“…Among nonhospitalized individuals, we found evidence to support the association of viral RNA load and infectious virus on some, but not all symptoms. Fever was…”
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