Search Results - "Goldberg, Michael F"

Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes by Zaitsev, Aleksandr, Chelushkin, Maksim, Dyikanov, Daniiar, Cheremushkin, Ilya, Shpak, Boris, Nomie, Krystle, Zyrin, Vladimir, Nuzhdina, Ekaterina, Lozinsky, Yaroslav, Zotova, Anastasia, Degryse, Sandrine, Kotlov, Nikita, Baisangurov, Artur, Shatsky, Vladimir, Afenteva, Daria, Kuznetsov, Alexander, Paul, Susan Raju, Davies, Diane L., Reeves, Patrick M., Lanuti, Michael, Goldberg, Michael F., Tazearslan, Cagdas, Chasse, Madison, Wang, Iris, Abdou, Mary, Aslanian, Sharon M., Andrewes, Samuel, Hsieh, James J., Ramachandran, Akshaya, Lyu, Yang, Galkin, Ilia, Svekolkin, Viktor, Cerchietti, Leandro, Poznansky, Mark C., Ataullakhanov, Ravshan, Fowler, Nathan, Bagaev, Alexander

“…Cellular deconvolution algorithms virtually reconstruct tissue composition by analyzing the gene expression of complex tissues. We present the decision tree…”
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Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential by Kotov, Dmitri I, Kotov, Jessica A, Goldberg, Michael F, Jenkins, Marc K

“…CD4 Th cells can have cytotoxic activity against cells displaying relevant peptide-MHC class II (p:MHCII) ligands. Cytotoxicity may be a property of Th1 cells…”
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A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis by Sweeney, Kari A, Dao, Dee N, Goldberg, Michael F, Hsu, Tsungda, Venkataswamy, Manjunatha M, Henao-Tamayo, Marcela, Ordway, Diane, Sellers, Rani S, Jain, Paras, Chen, Bing, Chen, Mei, Kim, John, Lukose, Regy, Chan, John, Orme, Ian M, Porcelli, Steven A, Jacobs, William R

“…New vaccine candidates are urgently needed for the control and prevention of Mycobacterium tuberculosis (Mtb) infection. Kari Sweeney and her colleagues now…”
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A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens by Arora, Pooja, Baena, Andres, Yu, Karl O.A., Saini, Neeraj K., Kharkwal, Shalu S., Goldberg, Michael F., Kunnath-Velayudhan, Shajo, Carreño, Leandro J., Venkataswamy, Manjunatha M., Kim, John, Lazar-Molnar, Eszter, Lauvau, Gregoire, Chang, Young-tae, Liu, Zheng, Bittman, Robert, Al-Shamkhani, Aymen, Cox, Liam R., Jervis, Peter J., Veerapen, Natacha, Besra, Gurdyal S., Porcelli, Steven A.

“…Many hematopoietic cell types express CD1d and are capable of presenting glycolipid antigens to invariant natural killer T cells (iNKT cells). However, the…”
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Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis by Weinger, Jason G, Brosnan, Celia F, Loudig, Olivier, Goldberg, Michael F, Macian, Fernando, Arnett, Heather A, Prieto, Anne L, Tsiperson, Vladislav, Shafit-Zagardo, Bridget

“…Axl, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific…”
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Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants by Jacobson, Lee S., Lima, Heriberto, Goldberg, Michael F., Gocheva, Vasilena, Tsiperson, Vladislav, Sutterwala, Fayyaz S., Joyce, Johanna A., Gapp, Bianca V., Blomen, Vincent A., Chandran, Kartik, Brummelkamp, Thijn R., Diaz-Griffero, Felipe, Brojatsch, Jürgen

“…Immunologic adjuvants are critical components of vaccines, but it remains unclear how prototypical adjuvants enhance the adaptive immune response. Recent…”
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Mycobacterium tuberculosis Central Metabolism Is Key Regulator of Macrophage Pyroptosis and Host Immunity by Maxson, Michelle E, Das, Lahari, Goldberg, Michael F, Porcelli, Steven A, Chan, John, Jacobs, Jr, William R

“…Metabolic dysregulation in results in increased macrophage apoptosis or pyroptosis. However, mechanistic links between virulence and bacterial metabolic…”
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Cerebrovascular Disease in COVID-19 by Goldberg, Michael F, Goldberg, Morton F, Cerejo, R, Tayal, A H

“…Coronavirus disease 19 (COVID-19) is a pandemic originating in Wuhan, China, in December 2019. Early reports suggest that there are neurologic manifestations…”
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Stem cell induced inflammatory hypertrophy of the cauda equina by Brumbaugh, Aaron D., Podolsky, Alan, Kulzer, Matthew H., Spearman, Michael P., Goldberg, Michael F., Chang, Warren M., Khatoon, Nazia, Dantey, Kossivi, Li, Charles Q.

“…Stem cell therapy can present clinicians with challenging clinical scenarios, as access to such treatments outpaces the research into their efficacy and safety…”
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Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells by Goldberg, Michael F., Roeske, Elizabeth K., Ward, Lauren N., Pengo, Thomas, Dileepan, Thamotharampillai, Kotov, Dmitri I., Jenkins, Marc K.

“…Salmonella enterica (Se) bacteria cause persistent intracellular infections while stimulating a robust interferon-γ-producing CD4+ T (Th1) cell response. We…”
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Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells by Krueger, Peter D., Goldberg, Michael F., Hong, Sung-Wook, Osum, Kevin C., Langlois, Ryan A., Kotov, Dmitri I., Dileepan, Thamotharampillai, Jenkins, Marc K.

“…Interferon-γ (IFN-γ)-producing CD4+ T helper-1 (Th1) cells are critical for protection from microbes that infect the phagosomes of myeloid cells. Current…”
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The Membrane Form of Tumor Necrosis Factor Is Sufficient to Mediate Partial Innate Immunity to Francisella tularensis Live Vaccine Strain by Cowley, Siobhán C., Goldberg, Michael F., Ho, J Anthony, Elkins, Karen L.

“…Here we characterize Francisella tularensis live vaccine strain (LVS) infection in total tumor necrosis factor (TNF) knockout (KO) mice and in transgenic mice…”
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Recurrent atraumatic compartment syndrome as a manifestation of genetic neuromuscular disease by Famili, Dennis T., Fernandez-Garcia, Miguel A., Vanegas, Maria, Goldberg, Michael F., Voermans, Nicol, Quinlivan, Ros, Jungbluth, Heinz

“…•We report recurrent atraumatic compartment syndrome as a presenting feature in patients with a RYR1-related disorder and McArdle disease, respectively.•We…”
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Imaging of acute ischemic stroke by Rudkin, Scott, Cerejo, Russell, Tayal, Ashis, Goldberg, Michael F.

“…For decades, imaging has been a critical component of the diagnostic evaluation and management of patients suspected of acute ischemic stroke (AIS). With each…”
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Neuroradiologic manifestations of COVID-19: what the emergency radiologist needs to know by Goldberg, Michael F., Goldberg, Morton F.

“…Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a global pandemic with a wide spectrum of…”
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Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection by Tubo, Noah J., Fife, Brian T., Pagan, Antonio J., Kotov, Dmitri I., Goldberg, Michael F., Jenkins, Marc K.

“…Infection elicits CD4⁺ memory T lymphocytes that participate in protective immunity. Although memory cells are the progeny of naïve T cells, it is unclear that…”
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Pancreatitis in RYR1-related disorders by Famili, Dennis T., Mistry, Arti, Gerasimenko, Oleg, Gerasimenko, Julia, Tribe, Rachel M., Kyrana, Eirini, Dhawan, Anil, Goldberg, Michael F., Voermans, Nicol, Willis, Tracey, Jungbluth, Heinz

“…Mutations in RYR1 encoding the ryanodine receptor (RyR) skeletal muscle isoform (RyR1) are a common cause of inherited neuromuscular disorders. Despite its…”
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Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death by Lima Jr, Heriberto, Jacobson, Lee, Goldberg, Michael, Chandran, Kartik, Diaz-Griffero, Felipe, Lisanti, Michael P., Brojatsch, Jürgen

“…The Nod-like receptor, Nlrp3, has been linked to inflammatory diseases and adjuvant-mediated immune responses. A wide array of structurally diverse agents does…”
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Response to letter to the editor, “Neuroradiologic Manifestations of COVID-19: What the Emergency Radiologist Needs to Know” by Goldberg, Michael F., Goldberg, Morton F.

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Correction to: Response to letter to the editor, “Neuroradiologic Manifestations of COVID-19: What the Emergency Radiologist Needs to Know” by Goldberg, Michael F., Goldberg, Morton F.

“…A Correction to this paper has been published: https://doi.org/10.1007/s10140-021-01901-w…”
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