Search Results - "Goldberg, Ilya G"

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway by Fang, Evandro F., Waltz, Tyler B., Kassahun, Henok, Lu, Qiping, Kerr, Jesse S., Morevati, Marya, Fivenson, Elayne M., Wollman, Bradley N., Marosi, Krisztina, Wilson, Mark A., Iser, Wendy B., Eckley, D. Mark, Zhang, Yongqing, Lehrmann, Elin, Goldberg, Ilya G., Scheibye-Knudsen, Morten, Mattson, Mark P., Nilsen, Hilde, Bohr, Vilhelm A., Becker, Kevin G.

“…Aging is a major international concern that brings formidable socioeconomic and healthcare challenges. Small molecules capable of improving the health of older…”
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Pattern recognition software and techniques for biological image analysis by Shamir, Lior, Delaney, John D, Orlov, Nikita, Eckley, D Mark, Goldberg, Ilya G

“…The increasing prevalence of automated image acquisition systems is enabling new types of microscopy experiments that generate large image datasets. However,…”
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WND-CHARM: Multi-purpose image classification using compound image transforms by Orlov, Nikita, Shamir, Lior, Macura, Tomasz, Johnston, Josiah, Eckley, D. Mark, Goldberg, Ilya G.

“…We describe a multi-purpose image classifier that can be applied to a wide variety of image classification tasks without modifications or fine-tuning, and yet…”
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Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells by Tokunaga, Kazuaki, Saitoh, Noriko, Goldberg, Ilya G., Sakamoto, Chiyomi, Yasuda, Yoko, Yoshida, Yoshinori, Yamanaka, Shinya, Nakao, Mitsuyoshi

“…Non-invasive evaluation of cell reprogramming by advanced image analysis is required to maintain the quality of cells intended for regenerative medicine. Here,…”
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Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA by Scheibye-Knudsen, Morten, Tseng, Anne, Jensen, Martin Borch, Scheibye-Alsing, Karsten, Fang, Evandro Fei, Iyama, Teruaki, Bharti, Sanjay Kumar, Marosi, Krisztina, Froetscher, Lynn, Kassahun, Henok, Eckley, David Mark, Maul, Robert W., Bastian, Paul, De, Supriyo, Ghosh, Soumita, Nilsen, Hilde, Goldberg, Ilya G., Mattson, Mark P., Wilson, David M., Brosh, Robert M., Gorospe, Myriam, Bohr, Vilhelm A.

“…Cockayne syndrome is a neurodegenerative accelerated aging disorder caused by mutations in the CSA or CSB genes. Although the pathogenesis of Cockayne syndrome…”
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Age-related changes of the retinal microvasculature by Orlov, Nikita V, Coletta, Cristopher, van Asten, Freekje, Qian, Yong, Ding, Jun, AlGhatrif, Majd, Lakatta, Edward, Chew, Emily, Wong, Wai, Swaroop, Anand, Fiorillo, Edoardo, Delitala, Alessandro, Marongiu, Michele, Goldberg, Ilya G, Schlessinger, David

“…Blood vessels of the retina provide an easily-accessible, representative window into the condition of microvasculature. We investigated how retinal vessel…”
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Bioimage informatics for experimental biology by Swedlow, Jason R, Goldberg, Ilya G, Eliceiri, Kevin W

“…Over the past twenty years there have been great advances in light microscopy with the result that multidimensional imaging has driven a revolution in modern…”
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IICBU 2008: a proposed benchmark suite for biological image analysis by Shamir, Lior, Orlov, Nikita, Mark Eckley, David, Macura, Tomasz J., Goldberg, Ilya G.

“…New technology for automated biological image acquisition has introduced the need for effective biological image analysis methods. These algorithms are…”
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Wndchrm - an open source utility for biological image analysis by Shamir, Lior, Orlov, Nikita, Eckley, D Mark, Macura, Tomasz, Johnston, Josiah, Goldberg, Ilya G

“…Biological imaging is an emerging field, covering a wide range of applications in biological and clinical research. However, while machinery for automated…”
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A rapid, high-throughput, viral infectivity assay using automated brightfield microscopy with machine learning by Dodkins, Rupert, Delaney, John R., Overton, Tess, Scholle, Frank, Frias-De-Diego, Alba, Crisci, Elisa, Huq, Nafisa, Jordan, Ingo, Kimata, Jason T., Findley, Teresa, Goldberg, Ilya G.

“…Infectivity assays are essential for the development of viral vaccines, antiviral therapies, and the manufacture of biologicals. Traditionally, these assays…”
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The actin family protein ARP6 contributes to the structure and the function of the nucleolus by Kitamura, Hiroshi, Matsumori, Haruka, Kalendova, Alzbeta, Hozak, Pavel, Goldberg, Ilya G., Nakao, Mitsuyoshi, Saitoh, Noriko, Harata, Masahiko

“…The actin family members, consisting of actin and actin-related proteins (ARPs), are essential components of chromatin remodeling complexes. ARP6, one of the…”
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Computational analysis of morphological and molecular features in gastric cancer tissues by Yasuda, Yoko, Tokunaga, Kazuaki, Koga, Tomoaki, Sakamoto, Chiyomi, Goldberg, Ilya G., Saitoh, Noriko, Nakao, Mitsuyoshi

“…Biological morphologies of cells and tissues represent their physiological and pathological conditions. The importance of quantitative assessment of…”
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Quantitative image analysis reveals distinct structural transitions during aging in Caenorhabditis elegans tissues by Johnston, Josiah, Iser, Wendy B, Chow, David K, Goldberg, Ilya G, Wolkow, Catherine A

“…Aging is associated with functional and structural declines in many body systems, even in the absence of underlying disease. In particular, skeletal muscles…”
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Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly by Matsumori, Haruka, Watanabe, Kenji, Tachiwana, Hiroaki, Fujita, Tomoko, Ito, Yuma, Tokunaga, Makio, Sakata-Sogawa, Kumiko, Osakada, Hiroko, Haraguchi, Tokuko, Awazu, Akinori, Ochiai, Hiroshi, Sakata, Yuka, Ochiai, Koji, Toki, Tsutomu, Ito, Etsuro, Goldberg, Ilya G, Tokunaga, Kazuaki, Nakao, Mitsuyoshi, Saitoh, Noriko

“…The nucleolus is the site of ribosome assembly and formed through liquid-liquid phase separation. Multiple ribosomal DNA (rDNA) arrays are bundled in the…”
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Loss of the integral nuclear envelope protein SUN1 induces alteration of nucleoli by Matsumoto, Ayaka, Sakamoto, Chiyomi, Matsumori, Haruka, Katahira, Jun, Yasuda, Yoko, Yoshidome, Katsuhide, Tsujimoto, Masahiko, Goldberg, Ilya G, Matsuura, Nariaki, Nakao, Mitsuyoshi, Saitoh, Noriko, Hieda, Miki

“…A supervised machine learning algorithm, which is qualified for image classification and analyzing similarities, is based on multiple discriminative…”
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Biological imaging software tools by Eliceiri, Kevin W, Berthold, Michael R, Goldberg, Ilya G, Ibáñez, Luis, Manjunath, B S, Martone, Maryann E, Murphy, Robert F, Peng, Hanchuan, Plant, Anne L, Roysam, Badrinath, Stuurman, Nico, Swedlow, Jason R, Tomancak, Pavel, Carpenter, Anne E

“…Representative members of the bioimage informatics community review the computational steps and some of the primary software tools available to biologists who…”
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Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative by Ashinsky, Beth G., Bouhrara, Mustapha, Coletta, Christopher E., Lehallier, Benoit, Urish, Kenneth L., Lin, Ping‐Chang, Goldberg, Ilya G., Spencer, Richard G.

“…ABSTRACT The purpose of this study is to evaluate the ability of a machine learning algorithm to classify in vivo magnetic resonance images (MRI) of human…”
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The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging by Goldberg, Ilya G, Allan, Chris, Burel, Jean-Marie, Creager, Doug, Falconi, Andrea, Hochheiser, Harry, Johnston, Josiah, Mellen, Jeff, Sorger, Peter K, Swedlow, Jason R

“…The Open Microscopy Environment (OME) defines a data model and a software implementation to serve as an informatics framework for imaging in biological…”
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Automatic detection of melanoma progression by histological analysis of secondary sites by Orlov, Nikita V., Weeraratna, Ashani T., Hewitt, Stephen M., Coletta, Christopher E., Delaney, John D., Mark Eckley, D., Shamir, Lior, Goldberg, Ilya G.

“…We present results from machine classification of melanoma biopsies sectioned and stained with hematoxylin/eosin (H&E) on tissue microarrays (TMA). The four…”
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Quantitative measurement of aging using image texture entropy by Shamir, Lior, Wolkow, Catherine A., Goldberg, Ilya G.

“…Motivation: A key element in understanding the aging of Caenorhabditis elegans is objective quantification of the morphological differences between younger and…”
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