Search Results - "Goldberg, I.J"

Statin Inhibition of Fc Receptor–Mediated Phagocytosis by Macrophages Is Modulated by Cell Activation and Cholesterol by Loike, J D, Shabtai, D Y, Neuhut, R, Malitzky, S, Lu, E, Husemann, J, Goldberg, I J, Silverstein, S C

“…OBJECTIVES—An inflammatory response to altered lipoproteins that accumulate in the arterial wall is a major component of the pathogenesis of atherosclerosis…”
Get full text

Lipoprotein lipase hydrolysis of retinyl ester: possible implications for retinoid uptake by cells by Blaner, W.S, Obunike, J.C, Kurlandsky, S.B, Al-Haideri, M, Piantedos, R, Deckelbaum, R.F, Goldberg, I.J

“…Adipose tissue contains substantial stores of retinoid (retinol + retinyl ester) that, quantitatively, are second only to retinoid stores in the liver. Our…”
Get full text

Effect Of Lipoprotein Lipase (Lpl) Deletion On Atherosclerosis Regression by Basu, D., Josefs, T., Fisher, E.A., Goldberg, I.J.

Get full text

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia by Beigneux, Anne P, Miyashita, Kazuya, Ploug, Michael, Blom, Dirk J, Ai, Masumi, Linton, MacRae F, Khovidhunkit, Weerapan, Dufour, Robert, Garg, Abhimanyu, McMahon, Maureen A, Pullinger, Clive R, Sandoval, Norma P, Hu, Xuchen, Allan, Christopher M, Larsson, Mikael, Machida, Tetsuo, Murakami, Masami, Reue, Karen, Tontonoz, Peter, Goldberg, Ira J, Moulin, Philippe, Charrière, Sybil, Fong, Loren G, Nakajima, Katsuyuki, Young, Stephen G

“…Six patients with severe hypertriglyceridemia (chylomicronemia) were found to have autoantibodies against a capillary endothelial-cell protein (GPIHBP1) that…”
Get full text

Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity by Bosma, Madeleen, Dapito, Dianne H., Drosatos-Tampakaki, Zoi, Huiping-Son, Ni, Huang, Li-Shin, Kersten, Sander, Drosatos, Konstantinos, Goldberg, Ira J.

“…We used human cardiomyocyte-derived cells to create an in vitro model to study lipid metabolism and explored the effects of PPARγ, ACSL1 and ATGL on fatty…”
Get full text

Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins by Obunike, J.C, Edwards, I.J, Rumsey, S.C, Curtiss, L.K, Wagner, W.D, Deckelbaum, R.J, Goldberg, I.J

“…Lipoprotein lipase (LPL) increases the cellular uptake and degradation of LDL by fibroblasts and macrophages via a heparin-sensitive process. The roles of the…”
Get full text

Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis by Goldberg, I.J. (Columbia University, New York, NY.)

“…Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes triglyceride in chylomicrons, during the past half decade there has been…”
Get full text

Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester by Van Bennekum, A.M, Kako, Y, Weinstock, P.H, Harrison, E.H, Deckelbaum, R.J, Goldberg, I.J, Blaner, W.S

“…Approximately 25% of postprandial retinoid is cleared from the circulation by extrahepatic tissues. Little is known about physiologic factors important to this…”
Get full text

Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase by Parthasarathy, N, Goldberg, I J, Sivaram, P, Mulloy, B, Flory, D M, Wagner, W D

“…Lipoprotein lipase (LpL) catalyzes the hydrolysis of triglycerides in plasma lipoproteins at the luminal surface of the vascular endothelium. This enzyme is…”
Get full text

The NH2-terminal region of apolipoprotein B is sufficient for lipoprotein association with glycosaminoglycans by Goldberg, I.J. (Columbia University College of Physicians and Surgeons, NY.), Wagner, W.D, Pang, L, Paka, L, Curtiss, L.K, DeLozier, J.A, Shelness, G.S, Young, C.S.H, Pillarisetti, S

“…An initial event in atherosclerosis is the retention of lipoproteins within the intima of the vessel wall. The co-localization of apolipoprotein (apo) B and…”
Get full text

3.P.300 Oxidized LDL and lysolecithin induced decrease in subendothelial heparan sulfate is due to the actions of an endothelial heparanase by Pillarisetti, S., Paka, S., Obunike, J., Goldberg, I.J.

Get full text

2.W18.3 Lipoprotein association with cells and matrix: Modulation by lipase and proteoglycans by Goldberg, I.J., Pillarisetti, S., Wagner, W.D., Rutledge, J.C.

Get full text

Routes of FA delivery to cardiac muscle: modulation of lipoprotein lipolysis alters uptake of TG-derived FA by Augustus, A.S, Kako, Y, Yagyu, H, Goldberg, I.J

Get full text

An amino-terminal fragment of apolipoprotein B binds to lipoprotein lipase and may facilitate its binding to endothelial cells by PILLARISETTI SIVARAM, CHOI, S. Y, CURTISS, L. K, GOLDBERG, I. J

“…Lipoprotein lipase (LPL), the principal enzyme which hydrolyzes triglycerides in circulating plasma lipoproteins, functions while bound to the luminal surface…”
Get full text

Identification and characterization of the endothelial cell surface lipoprotein lipase receptor by SAXENA, U, KLEIN, M. G, GOLDBERG, I. J

“…The hydrolysis of triglycerides in plasma lipoproteins is mediated by lipoprotein lipase (LPL) that is bound to vascular endothelial cells. The specific…”
Get full text

Transport of Lipoprotein Lipase Across Endothelial Cells by Saxena, Uday, Klein, Michael G., Goldberg, Ira J.

“…Lipoprotein lipase (LPL), synthesized in muscle and fat, hydrolyzes plasma triglycerides primarily while bound to luminal endothelial cell surfaces. To obtain…”
Get full text

AHA Scientific Statement. AHA Dietary Guidelines. Revision 2000: Astatement for healthcare professionals from the nutrition committee ofthe American Heart Association by Krauss, R.M., Eckel, R.H., Howard, B., Appel, L.J., Daniels,S.R., Deckelbaum, R.J., Erdman, J.W., Kris-Etherton, P., Goldberg, I.J., Kotchen, T.A., Lichtenstein, A.H., Mitch, W.E., Mullis, R., Robinson, K., Wylie-Rosett, J., St. Jeor, S., Suttie, J., Tribble, D.L., Bazzarre, T.L.

Get full text

Identification of a heparin-releasable lipoprotein lipase binding protein from endothelial cells by SIVARAM, P, KLEIN, M. G, GOLDBERG, I. J

“…Triglycerides in circulating plasma lipoproteins are hydrolyzed by lipoprotein lipase (LPL) which is thought to bind to proteoglycans on the luminal…”
Get full text

Lipoprotein lipase release from BFC-1 beta adipocytes. Effects of triglyceride-rich lipoproteins and lipolysis products by SASAKI, A, GOLDBERG, I. J

“…Lipoprotein lipase (LPL), synthesized by adipocytes and myocytes, must be transported to the luminal endothelial cell surface where it then interacts with…”
Get full text

Specificity of lipoprotein lipase binding to endothelial cells by STINS, M. F, SIVARAM, P, SASAKI, A, GOLDBERG, I. J

“…Lipoprotein lipase (LPL) hydrolyzes circulating lipoprotein triglyceride molecules while it is associated with the luminal surface of capillary endothelial…”
Get full text