Search Results - "Gold, James"
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A Meta-Analysis of Mismatch Negativity in Schizophrenia: From Clinical Risk to Disease Specificity and Progression
Published in Biological psychiatry (1969) (15-06-2016)“…Abstract Background The observation that mismatch negativity (MMN) is consistently impaired in schizophrenia has generated considerable interest in the use of…”
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A New Perspective on Anhedonia in Schizophrenia
Published in The American journal of psychiatry (01-04-2012)“…The finding that patients with schizophrenia report levels of current pleasure comparable to those of healthy subjects but report less pleasure in past or…”
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The Latent Structure of Negative Symptoms in Schizophrenia
Published in JAMA psychiatry (Chicago, Ill.) (01-12-2018)“…Negative symptoms are associated with a range of poor clinical outcomes, and currently available treatments generally do not produce a clinically meaningful…”
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Studying Healthy Psychosislike Experiences to Improve Illness Prediction
Published in JAMA psychiatry (Chicago, Ill.) (01-05-2023)“…Distinguishing delusions and hallucinations from unusual beliefs and experiences has proven challenging. The advent of neural network and generative modeling…”
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A Psychometric Comparison of the Clinical Assessment Interview for Negative Symptoms and the Brief Negative Symptom Scale
Published in Schizophrenia bulletin (01-11-2016)“…In 2005, the National Institute of Mental Health held a consensus development conference on negative symptoms of schizophrenia. Among the important conclusions…”
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The Hyperfocusing Hypothesis: A New Account of Cognitive Dysfunction in Schizophrenia
Published in Schizophrenia bulletin (11-09-2019)“…Impairments in basic cognitive processes such as attention and working memory are commonly observed in people with schizophrenia and are predictive of…”
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The Construct of Attention in Schizophrenia
Published in Biological psychiatry (01-07-2008)“…Schizophrenia is widely thought to involve deficits of attention. However, the term “attention” can be defined so broadly that impaired performance on…”
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A Review of Reward Processing and Motivational Impairment in Schizophrenia
Published in Schizophrenia bulletin (01-03-2014)“…This article reviews and synthesizes research on reward processing in schizophrenia, which has begun to provide important insights into the cognitive and…”
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Effort Cost Computation in Schizophrenia: A Commentary on the Recent Literature
Published in Biological psychiatry (1969) (01-12-2015)“…Abstract The cognitive and affective factors implicated in the motivational impairments seen in many people with schizophrenia remain poorly understood. Many…”
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Negative Symptoms of Schizophrenia Are Associated with Abnormal Effort-Cost Computations
Published in Biological psychiatry (1969) (15-07-2013)“…Background Decision-making studies show that response selection is influenced by the “effort cost” associated with response alternatives. These effort-cost…”
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Working memory contributions to reinforcement learning impairments in schizophrenia
Published in The Journal of neuroscience (08-10-2014)“…Previous research has shown that patients with schizophrenia are impaired in reinforcement learning tasks. However, behavioral learning curves in such tasks…”
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The roles of reward, default, and executive control networks in set-shifting impairments in schizophrenia
Published in PloS one (27-02-2013)“…Patients with schizophrenia (SZ) show deficits on tasks of rapid reinforcement learning, like probabilistic reversal learning (PRL), but the neural bases for…”
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Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia
Published in Schizophrenia bulletin (01-09-2015)“…Because negative symptoms, including motivational deficits, are a critical unmet need in schizophrenia, there are many ongoing efforts to develop new…”
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Neuropsychological Impairments in Schizophrenia and Psychotic Bipolar Disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Study
Published in The American journal of psychiatry (01-11-2013)“…ObjectiveFamilial neuropsychological deficits are well established in schizophrenia but remain less well characterized in other psychotic disorders. This study…”
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Network Analysis Reveals Which Negative Symptom Domains Are Most Central in Schizophrenia vs Bipolar Disorder
Published in Schizophrenia bulletin (24-10-2019)“…Network analysis was used to examine how densely interconnected individual negative symptom domains are, whether some domains are more central than others, and…”
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Impaired Activation in Cognitive Control Regions Predicts Reversal Learning in Schizophrenia
Published in Schizophrenia bulletin (01-03-2016)“…Reinforcement learning deficits have been associated with schizophrenia (SZ). However, the pathophysiology that gives rise to these abnormalities remains…”
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Posterior Parietal Cortex Dysfunction Is Central to Working Memory Storage and Broad Cognitive Deficits in Schizophrenia
Published in The Journal of neuroscience (26-09-2018)“…PFC dysfunction is widely believed to underlie working memory (WM) deficits in people with schizophrenia (PSZ), but few studies have focused on measures of WM…”
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Is Attentional Filtering Impaired in Schizophrenia?
Published in Schizophrenia bulletin (11-09-2019)“…Recent evidence suggests that schizophrenia involves hyperfocusing, an unusually narrow but intense focusing of processing resources. This appears to…”
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Neuropsychological Performance Among Individuals at Clinical High-Risk for Psychosis vs Putatively Low-Risk Peers With Other Psychopathology: A Systematic Review and Meta-Analysis
Published in Schizophrenia bulletin (01-09-2022)“…Abstract Background and Hypothesis Youth at clinical high-risk (CHR) for psychosis present with neuropsychological impairments relative to healthy controls…”
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Cognitive deficits as treatment targets in schizophrenia
Published in Schizophrenia research (15-12-2004)“…Cognitive impairment has emerged as an important new target in schizophrenia therapeutics in light of evidence that cognitive deficits are critically related…”
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