Search Results - "Golbe, L"

Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) : Report of the NINDS-SPSP international workshop by LITVAN, I, AGID, Y, HALLETT, M, JANKOVIC, J, QUINN, N. P, TOLOSA, E, ZEE, D. S, CALNE, D, CAMPBELL, G, DUBOIS, B, DUVOISIN, R. C, GOETZ, C. G, GOLBE, L. I, GRAFMAN, J, GROWDON, J. H

“…To improve the specificity and sensitivity of the clinical diagnosis of progressive supranuclear palsy (PSP, Steele-Richardson-Olszewski syndrome), the…”
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Mutation in the α-synuclein gene identified in families with Parkinson's disease by POLYMEROPOULOS, M. H, LAVEDAN, C, STENROOS, E. S, CHANDRASEKHARAPPA, S, ATHANASSIADOU, A, PAPAPETROPOULOS, T, JOHNSON, W. G, LAZZARINI, A. M, DUVOISIN, R. C, DI LORIO, G, GOLBE, L. I, NUSSBAUM, R. L, LEROY, E, IDE, S. E, DEHEJIA, A, DUTRA, A, PIKE, B, ROOT, H, RUBENSTEIN, J, BOYER, R

“…Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern of familial aggregation has…”
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Mapping of a Gene for Parkinson's Disease to Chromosome 4q21-q23 by Polymeropoulos, Mihael H., Higgins, Joseph J., Golbe, Lawrence I., Johnson, William G., Ide, Susan E., Di Iorio, Giuseppe, Sanges, Giuseppe, Stenroos, Edward S., Pho, Lana T., Schaffer, Alejandro A., Lazzarini, Alice M., Nussbaum, Robert L., Duvoisin, Roger C.

“…Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting approximately 1 percent of the population…”
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Widespread Alterations of α-Synuclein in Multiple System Atrophy by Dickson, D.W., Liu, W.-K., Hardy, J., Farrer, M., Mehta, N., Uitti, R., Mark, M., Zimmerman, T., Golbe, L., Sage, J., Sima, A., D'Amato, C., Albin, R., Gilman, S., Yen, S.-H.

“…Glial cytoplasmic inclusions (GCI) are the hallmark of multiple system atrophy (MSA), a rare movement disorder frequently associated with autonomic…”
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BDNF genetic variants are associated with onset age of familial Parkinson disease : GenePD Study by KARAMOHAMED, S, LATOURELLE, J. C, GUTTMAN, M, NICHOLSON, G, WILK, J. B, SAINT-HILAIRE, M, DESTEFANO, A. L, PRAKASH, R, TOBIN, S, WILLIAMSON, J, SUCHOWERSKY, O, LABELL, N, RACETTE, B. A, GROWDON, B. N. J, SINGER, C, WATTS, R, GOLDWURM, S, PEZZOLI, G, BAKER, K. B, GIROUX, M. L, PRAMSTALLER, P. P, BURN, D. J, CHINNERY, P, PERLMUTTER, J. S, SHERMAN, S, VIEREGGE, P, LITVAN, I, GUSELLA, J. F, MYERS, R. H, PARSIAN, A, WOOTEN, G. F, LEW, M, KLEIN, C, SHILL, H, GOLBE, L. I, MARK, M. H

“…Brain-derived neurotrophic factor (BDNF) stimulates neuronal growth and protects nigral dopamine neurons in animal models of Parkinson disease (PD). Therefore,…”
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Genome-wide scan for Parkinson's disease: The genePD Study by DESTEFANO, A. L, GOLBE, L. I, LAFONTAINE, A. L, LABELLE, N, LEW, M. F, WATERS, C. H, GROWDON, J. H, SINGER, C, CURRIE, L. J, WOOTEN, G. F, VIEREGGE, P, PRAMSTALLER, P. P, MARK, M. H, KLEIN, C, HUBBLE, J. P, STACY, M, MONTGOMERY, E, MACDONALD, M. E, GUSELLA, J. F, MYERS, R. H, LAZZARINI, A. M, MAHER, N. E, SAINT-HILAIRE, M, FELDMAN, R. G, GUTTMAN, M, WATTS, R. L, SUCHOWERSKY, O

“…A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214…”
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Epidemiologic study of 203 sibling pairs with Parkinson's disease: The GenePD study by MAHER, N. E, GOLBE, L. I, FELDMAN, R. G, GUTTMAN, M, LEW, M, SCHUMAN, S, SUCHOWERSKY, O, LAFONTAINE, A. L, LABELLE, N, VIEREGGE, P, PRAMSTALLER, P. P, KLEIN, C, LAZZARINI, A. M, HUBBLE, J, REIDER, C, GROWDON, J, WATTS, R, MONTGOMERY, E, BAKER, K, SINGER, C, STACY, M, MYERS, R. H, MARK, M. H, CURRIE, L. J, WOOTEN, G. F, SAINT-HILAIRE, M, WILK, J. B, VOLCJAK, J, MAHER, J. E

“…To examine patterns of familial aggregation and factors influencing onset age in a sample of siblings with PD. Sibling pairs (n = 203) with PD were collected…”
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Mitochondrial Dysfunction in Cybrid Lines Expressing Mitochondrial Genes from Patients with Progressive Supranuclear Palsy by Swerdlow, R. H., Golbe, L. I., Parks, J. K., Cassarino, D. S., Binder, D. R., Grawey, A. E., Litvan, I., Bennett, J. P., Wooten, G. F., Parker, W. D.

“…: Progressive supranuclear palsy (PSP) is a neurodegenerative movement disorder of unknown etiology. We hypothesized that mitochondrial DNA (mtDNA) aberration…”
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Clinical genetic analysis of Parkinson's disease in the Contursi kindred by Golbe, L I, Di Iorio, G, Sanges, G, Lazzarini, A M, La Sala, S, Bonavita, V, Duvoisin, R C

“…We performed a clinical genetic analysis of a kindred originating in the town of Contursi in Salerno province, Italy, in which 60 individuals in 5 generations…”
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Alpha-synuclein and Parkinson's disease by Golbe, Lawrence I.

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Herbicide exposure modifies GSTP1 haplotype association to parkinson onset age : The GenePD study by WILK, J. B, TOBIN, J. E, SINGER, C, GROWDON, J. H, LATOURELLE, J. C, SAINT-HILAIRE, M. H, DESTEFANO, A. L, PRAKASH, R, WILLIAMSON, S, BERG, C. J, SUN, M, GOLDWURM, S, SUCHOWERSKY, O, PEZZOLI, G, RACETTE, B. A, PERLMUTTER, J. S, PARSIAN, A, BAKER, K. B, GIROUX, M. L, LITVAN, I, PRAMSTALLER, P. P, NICHOLSON, G, BURN, D. J, SHILL, H. A, CHINNERY, P. F, VIEREGGE, P, SLEVIN, J. T, CAMBI, F, MACDONALD, M. E, GUSELLA, J. F, MYERS, R. H, GOLBE, L. I, KLEIN, C, WOOTEN, G. F, LEW, M. F, MARK, M. H, GUTTMAN, M, WATTS, R. L

“…Polymorphisms in the glutathione S-transferase pi gene (GSTP1), encoding GSTP1-1, a detoxification enzyme, may increase the risk of Parkinson disease (PD) with…”
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A haplotype at the PARK3 locus influences onset age for Parkinson's disease: The GenePD study by KARAMOHAMED, S, DESTEFANO, A. L, CURRIE, L. J, WOOTEN, G. F, STACY, M, SAINT-HILAIRE, M, FELDMAN, R. G, SULLIVAN, K. M, XU, G, WATTS, R, GROWDON, J, LEW, M, WILK, J. B, WATERS, C, VIEREGGE, P, PRAMSTALLER, P. P, KLEIN, C, RACETTE, B. A, PERLMUTTER, J. S, PARSIAN, A, SINGER, C, MONTGOMERY, E, BAKER, K, SHOEMAKER, C. M, GUSELLA, J. F, FINK, S. J, MYERS, R. H, HERBERT, A, GOLBE, L. I, MARK, M. H, LAZZARINI, A. M, SUCHOWERSKY, O, LABELLE, N, GUTTMAN, M

“…To identify a haplotype influencing onset age for Parkinson's disease (PD) in the PARK3 region on chromosome 2p13. Single nucleotide polymorphisms (SNP)…”
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An extended 5'-tau susceptibility haplotype in progressive supranuclear palsy by HIGGINS, J. J, GOLBE, L. I, DE BIASE, A, JANKOVIC, J, FACTOR, S. A, ADLER, R. L

“…To confirm the association of an extended 5'-tau haplotype on chromosome 17q with the disease phenotype in clinically ascertained individuals with sporadic…”
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Variable expression of Parkinson's disease : a base-line analysis of the DATATOP cohort by JANKOVIC, J, MCDERMOTT, M, STERN, M, TANNER, C, WEINER, W, CARTER, J, GAUTHIER, S, GOETZ, C, GOLBE, L, HUBER, S, KOLLER, W, OLANOW, C, SHOULSON, I

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Olfactory testing differentiates between progressive supranuclear palsy and idiopathic Parkinson's disease by DOTY, R. L, GOLBE, L. I, MCKEOWN, D. A, STERN, M. B, LEHRACH, C. M, CRAWFORD, D

“…Olfactory dysfunction occurs in most patients with idiopathic Parkinson's disease (PD). In this study, we sought to determine whether such dysfunction is also…”
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Dopamine-related personality traits in Parkinson's disease by MENZA, M. A, GOLBE, L. I, CODY, R. A, FORMAN, N. E

“…Studies suggest that Parkinson's disease (PD) is associated with a particular group of personality characteristics. With relative uniformity, PD patients are…”
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A clinical genetic study of Parkinson's disease : evidence for dominant transmission by LAZZARINI, A. M, MYERS, R. H, ZIMMERMAN, T. R, MARK, M. H, GOLBE, L. I, SAGE, J. I, JOHNSON, W. G, DUVOISIN, R. C

“…We used a family history questionnaire, semi-structured interview, and personal examination of secondary cases to collect data on the prevalence of Parkinson's…”
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Debt, Operating Margin, and Investment In Workplace Safety by Filer, Randall K., Golbe, Devra L.

“…We investigate how a firm's financial performance affects workplace safety. We provide empirical estimates of the relationship between a firm's financial…”
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A large kindred with autosomal dominant Parkinson's disease by Golbe, L I, Di Iorio, G, Bonavita, V, Miller, D C, Duvoisin, R C

“…We report two large kindreds with Parkinson's disease (PD) apparently inherited in autosomal dominant fashion. Forty-one persons in four generations have been…”
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Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study by Karamohamed, Samer, Golbe, L.I., Mark, M.H., Lazzarini, A.M., Suchowersky, O., Labelle, N., Guttman, Mark, Currie, L.J., Wooten, G.F., Stacy, M., Saint-Hilaire, M., Feldman, R.G., Liu, J., Shoemaker, C.M., Wilk, J.B., DeStefano, A.L., Latourelle, J.C., Xu, G., Watts, R., Growdon, J., Lew, M., Waters, C., Vieregge, P., Pramstaller, P.P., Klein, C., Racette, B.A., Perlmutter, J.S., Parsian, A., Singer, Carlos, Montgomery, E., Baker, K., Gusella, J.F., Herbert, A., Myers, R.H.

“…Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of…”
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