Search Results - "Golas, Aaron"
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Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
Published in ACS chemical biology (17-08-2012)“…Despite the urgent need for new antitubercular drugs, few are on the horizon. To combat the problem of emerging drug resistance, structurally unique chemical…”
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Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence
Published in PLoS pathogens (01-05-2017)“…A key to the pathogenic success of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is the capacity to survive within host macrophages…”
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High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020
Published in mBio (25-04-2023)“…The ability to measure neutralizing antibodies on large scale can be important for understanding features of the natural history and epidemiology of infection,…”
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The Sensor Kinase KinB Regulates Virulence in Acute Pseudomonas aeruginosa Infection
Published in Journal of Bacteriology (01-06-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes
Published in Nature (London) (01-07-2019)“…New antibiotics are needed to combat rising levels of resistance, with new Mycobacterium tuberculosis (Mtb) drugs having the highest priority. However,…”
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Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model
Published in ACS chemical biology (18-10-2013)“…During Mycobacterium tuberculosis infection, a population of bacteria is thought to exist in a nonreplicating state, refractory to antibiotics, which may…”
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Identification of novel inhibitors of non-replicating Mycobacterium tuberculosis using a carbon starvation model
Published in ACS chemical biology (13-08-2013)“…During Mycobacterium tuberculosis infection, a population of bacteria is thought to exist in a non-replicating state, refractory to antibiotics, which may…”
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