Search Results - "Golakoti, T"

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro by Madlener, S, Saiko, P, Vonach, C, Viola, K, Huttary, N, Stark, N, Popescu, R, Gridling, M, Vo, N T-P, Herbacek, I, Davidovits, A, Giessrigl, B, Venkateswarlu, S, Geleff, S, Jäger, W, Grusch, M, Kerjaschki, D, Mikulits, W, Golakoti, T, Fritzer-Szekeres, M, Szekeres, T, Krupitza, G

“…Background: Digalloyl-resveratrol (di-GA) is a synthetic compound aimed to combine the biological effects of the plant polyhydroxy phenols gallic acid and…”
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Preclinical anticancer activity of cryptophycin-8 by Corbett, T H, Valeriote, F A, Demchik, L, Polin, L, Panchapor, C, Pugh, S, White, K, Knight, J, Jones, J, Jones, L, LoRusso, P, Foster, B, Wiegand, R A, Lisow, L, Golakoti, T, Heltzel, C E, Ogino, J, Patterson, G M, Moore, R E

“…Cryptophycin-8 was prepared by the conversion of the epoxide group on cryptophycin-1 to a chlorohydrin. In the studies reported here, cryptophycin-8 was…”
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Neuroprotective and antiinflammatory properties of a novel demethylated curcuminoid by Khanna, Savita, Park, Han-A, Sen, Chandan K, Golakoti, Trimurtulu, Sengupta, Krishanu, Venkateswarlu, Somepalli, Roy, Sashwati

“…A demethylated derivative of curcumin (DC; 67.8% bisdemethylcurcumin, 20.7% demethylmonodemethoxycurcumin, 5.86% bisdemethoxycurcumin, 2.58% demethylcurcumin)…”
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Biosynthesis of 4-Methylproline in Cyanobacteria:  Cloning of nosE and nosF Genes and Biochemical Characterization of the Encoded Dehydrogenase and Reductase Activities by LUESCH, Hendrik, HOFFMANN, Dietmar, HEVEL, Joan M., BECKER, Julia E., GOLAKOTI, Trimurtulu, MOORE, Richard E.

“…The biosynthesis of the unusual amino acid 4-methylproline in the Nostoc genus of cyanobacteria was investigated on the genetic and enzymatic level. Two genes…”
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Isolation and Structure Determination of Cryptophycins 38, 326, and 327 from the Terrestrial Cyanobacterium Nostoc sp. GSV 224 by Chaganty, Sreedhara, Golakoti, Trimurtulu, Heltzel, Carl, Moore, Richard E, Yoshida, Wesley Y

“…Cryptophycin-38 (2), -326 (3), and -327 (4) are three new trace constituents of the terrestrial cyanobacterium Nostoc sp. GSV 224. Cryptophycin-38 is a…”
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A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin registered for treatment of osteoarthritis of the knee by Sengupta, K, Alluri, K V, Satish, A R, Mishra, S, Golakoti, T, Sarma, KVS, Dey, D, Raychaudhuri, S P

“…Introduction 5-Loxin registered is a novel Boswellia serrata extract enriched with 30% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA), which exhibits potential…”
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A Convergent Approach to Cryptophycin 52 Analogues:  Synthesis and Biological Evaluation of a Novel Series of Fragment A Epoxides and Chlorohydrins by Al-awar, Rima S, Ray, James E, Schultz, Richard M, Andis, Sherri L, Kennedy, Joseph H, Moore, Richard E, Liang, Jian, Golakoti, Trimurtulu, Subbaraju, Gottumukkala V, Corbett, Thomas H

“…Cryptophycin 52 is a synthetic derivative of Cryptophycin 1, a potent antimicrotubule agent isolated from cyanobacteria. In an effort to increase the potency…”
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Structure determination, conformational analysis, chemical stability studies, and antitumor evaluation of the cryptophycins. Isolation of 18 new analogs from Nostoc sp. strain GSV 224 by Golakoti, Trimurtulu, Ogino, Junichi, Heltzel, Carl E, Le Husebo, Trang, Jensen, Craig M, Larsen, Linda K, Patterson, Gregory M. L, Moore, Richard E, Mooberry, Susan L, Corbett, Thomas H, Valeriote, Frederick A

“…Using a modified isolation procedure devoid of methanol, 18 new cyclic cryptophycins have been isolated from Nostoc sp. GSV 224 as minor constituents in…”
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Isolation and Structure Determination of Nostocyclopeptides A1 and A2 from the Terrestrial Cyanobacterium Nostoc sp. ATCC53789 by Golakoti, Trimurtulu, Yoshida, Wesley Y, Chaganty, Sreedhara, Moore, Richard E

“…The isolation and total structure determination of nostocyclopeptides A1 (1) and A2 (2) are described. These cyclic heptapeptides, which possess a unique imino…”
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Isolation and Structures of Nostopeptolides A1, A2 and A3 from the Cyanobacterium Nostoc sp. GSV224 by Golakoti, Trimurtulu, Yoshida, Wesley Y., Chaganty, Sreedhara, Moore, Richard E.

“…The isolation and total structure determinations of nostopeptolides A1 ( 1), A2 ( 2) and A3 ( 3) are described. These cyclic depsipeptides, which are devoid of…”
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Three New Cryptophycins from Nostoc sp. GSV 224 by Subbaraju, Gottumukkala V, Golakoti, Trimurtulu, Patterson, Gregory M. L, Moore, Richard E

“…Cryptophycin 46 (2), -175 (3), and -176 (4) have been identified as three new trace constituents of Nostoc sp. GSV 224. Cryptophycin-46 is an epimer of…”
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Treatment of human prostate tumors PC-3 and TSU-PR1 with standard and investigational agents in SCID mice by POLIN, L, VALERIOTE, F, GOLAKOTI, T, PATTERSON, G, MOORE, R, CORBETT, T. H, WHITE, K, PANCHAPOR, C, PUGH, S, KNIGHT, J, LORUSSO, P, HUSSAIN, M, LIVERSIDGE, E, PELTIER, N

“…Both the PC-3 and the TSU-PR1 prostate tumor models were found to be satisfactory for chemotherapeutic investigations in ICR-SCID mice. The 30 to 60 mg…”
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Discovery of cryptophycin-1 and BCN-183577 : Examples of strategies and problems in the detection of antitumor activity in mice by CORBETT, T. H, VALERIOTE, F. A, WENTLAND, M, GOLAKOTI, T, HETZEL, C, OGINO, J, PATTERSON, G, MOORE, R, DEMCHIK, L, LOWICHIK, N, POLIN, L, PANCHAPOR, C, PUGH, S, WHITE, K, KUSHNER, J, RAKE, J

“…Historically, many new anticancer agents were first detected in a prescreen; usually consisting of a molecular/biochemical target or a cellular cytotoxicity…”
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