Search Results - "Golabek, Michael"

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies by Sanders, Rogier W, Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, de Val, Natalia, Kim, Helen J, Blattner, Claudia, de la Peña, Alba Torrents, Korzun, Jacob, Golabek, Michael, de Los Reyes, Kevin, Ketas, Thomas J, van Gils, Marit J, King, C Richter, Wilson, Ian A, Ward, Andrew B, Klasse, P J, Moore, John P

“…A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to induce broadly neutralizing…”
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Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C by Klasse, P J, LaBranche, Celia C, Ketas, Thomas J, Ozorowski, Gabriel, Cupo, Albert, Pugach, Pavel, Ringe, Rajesh P, Golabek, Michael, van Gils, Marit J, Guttman, Miklos, Lee, Kelly K, Wilson, Ian A, Butera, Salvatore T, Ward, Andrew B, Montefiori, David C, Sanders, Rogier W, Moore, John P

“…We have investigated the immunogenicity in rabbits of native-like, soluble, recombinant SOSIP.664 trimers based on the env genes of four isolates of human…”
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Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers by Go, Eden P, Ding, Haitao, Zhang, Shijian, Ringe, Rajesh P, Nicely, Nathan, Hua, David, Steinbock, Robert T, Golabek, Michael, Alin, James, Alam, S Munir, Cupo, Albert, Haynes, Barton F, Kappes, John C, Moore, John P, Sodroski, Joseph G, Desaire, Heather

“…HIV-1 envelope glycoprotein (Env) glycosylation is important because individual glycans are components of multiple broadly neutralizing antibody epitopes,…”
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Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens by Julien, Jean-Philippe, Lee, Jeong Hyun, Ozorowski, Gabriel, Hua, Yuanzi, de la Peña, Alba Torrents, de Taeye, Steven W., Nieusma, Travis, Cupo, Albert, Yasmeen, Anila, Golabek, Michael, Pugach, Pavel, Klasse, P. J., Moore, John P., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.

“…A key challenge in the quest toward an HIV-1 vaccine is design of immunogens that can generate a broadly neutralizing antibody (bnAb) response against the…”
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A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene by Pugach, Pavel, Ozorowski, Gabriel, Cupo, Albert, Ringe, Rajesh, Yasmeen, Anila, de Val, Natalia, Derking, Ronald, Kim, Helen J, Korzun, Jacob, Golabek, Michael, de Los Reyes, Kevin, Ketas, Thomas J, Julien, Jean-Philippe, Burton, Dennis R, Wilson, Ian A, Sanders, Rogier W, Klasse, P J, Ward, Andrew B, Moore, John P

“…Recombinant trimeric mimics of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) spike should expose as many epitopes as possible for…”
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Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro by Ozorowski, Gabriel, Cupo, Albert, Golabek, Michael, LoPiccolo, Michelle, Ketas, Thomas A, Cavallary, Matt, Cottrell, Christopher A, Klasse, P J, Ward, Andrew B, Moore, John P

“…Native-like, soluble, recombinant SOSIP trimers of various designs and based on several genes of human immunodeficiency virus type 1 (HIV-1) are being tested…”
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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo by Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W, Del Moral-Sanchez, Ivan, McGuire, Andrew T, Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L G M, Freund, Natalia T, Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D, Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J, Pritchard, Laura K, Stanfield, Robyn L, Crispin, Max, Ward, Andrew B, Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P, Nemazee, David, Nussenzweig, Michel C, Wilson, Ian A, Sanders, Rogier W

“…Induction of broadly neutralizing antibodies (bNAbs) by HIV-1 envelope glycoprotein immunogens would be a major advance toward an effective vaccine. A critical…”
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Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes by Ringe, Rajesh P, Ozorowski, Gabriel, Yasmeen, Anila, Cupo, Albert, Cruz Portillo, Victor M, Pugach, Pavel, Golabek, Michael, Rantalainen, Kimmo, Holden, Lauren G, Cottrell, Christopher A, Wilson, Ian A, Sanders, Rogier W, Ward, Andrew B, Klasse, P J, Moore, John P

“…Soluble, recombinant native-like envelope glycoprotein (Env) trimers of various human immunodeficiency virus type 1 (HIV-1) genotypes are being developed for…”
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Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies by Chung, Nancy P Y, Matthews, Katie, Kim, Helen J, Ketas, Thomas J, Golabek, Michael, de Los Reyes, Kevin, Korzun, Jacob, Yasmeen, Anila, Sanders, Rogier W, Klasse, Per Johan, Wilson, Ian A, Ward, Andrew B, Marozsan, Andre J, Moore, John P, Cupo, Albert

“…Recombinant soluble, cleaved HIV-1 envelope glycoprotein SOSIP.664 gp140 trimers based on the subtype A BG505 sequence are being studied structurally and…”
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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo by Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W., Del Moral-Sanchez, Ivan, McGuire, Andrew T., Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L. G. M., Freund, Natalia T., Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D., Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J., Pritchard, Laura K., Stanfield, Robyn L., Crispin, Max, Ward, Andrew B., Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P., Nemazee, David, Nussenzweig, Michel C., Wilson, Ian A., Sanders, Rogier W.

“…Induction of broadly neutralizing antibodies (bNAbs) by HIV-1 envelope glycoprotein immunogens would be a major advance toward an effective vaccine. A critical…”
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A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies: e1003618 by Sanders, Rogier W, Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, Val, Natalia de, Kim, Helen J, Blattner, Claudia, Peña, Torrents dela, Korzun, Jacob, Golabek, Michael, Reyes, Kevin delos, Ketas, Thomas J, Gils, Marit Jvan, King, C Richter, Wilson, Ian A, Ward, Andrew B, Klasse, P J, Moore, John P

“…A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to induce broadly neutralizing…”
Get full text