Search Results - "Gois, Pedro M.P."

Bioconjugation with Maleimides: A Useful Tool for Chemical Biology by Ravasco, João M. J. M., Faustino, Hélio, Trindade, Alexandre, Gois, Pedro M. P.

“…Maleimide chemistry stands out in the bioconjugation toolbox by virtue of its synthetic accessibility, excellent reactivity, and practicability. The…”
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Unveiling the Potential of Transition Metal Complexes for Medicine: Translational in Situ Activation of Metal‐Based Drugs from Bench to in Vivo Applications by Silva, Maria J. S. A., Gois, Pedro M. P., Gasser, Gilles

“…The development of metal‐based anticancer drugs has been hampered, among other reasons, by their lack of selectivity for cancer cells. In a recent article, Zou…”
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Cysteine-Selective Reactions for Antibody Conjugation by Cal, Pedro M. S. D., Bernardes, Gonçalo J. L., Gois, Pedro M. P.

“…Moving tracks from maleimide: New site‐selective protein modification reactions at cysteine have been developed. Unlike conventional maleimide conjugation,…”
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Efficient Amino‐Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS‐Activated Acrylamides by Silva, Maria J. S. A., Faustino, Hélio, Coelho, Jaime A. S., Pinto, Maria V., Fernandes, Adelaide, Compañón, Ismael, Corzana, Francisco, Gasser, Gilles, Gois, Pedro M. P.

“…Widely used reagents in the peptide functionalization toolbox, Michael acceptors and N‐hydroxysuccinimide (NHS) activated esters, are combined in NHS‐activated…”
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Engineering Boron Hot Spots for the Site‐Selective Installation of Iminoboronates on Peptide Chains by Russo, Roberto, Padanha, Rita, Fernandes, Fábio, Veiros, Luis F., Corzana, Francisco, Gois, Pedro M. P.

“…Boronic acids (BAs) are a promising bioconjugation function to design dynamic materials as they can establish reversible covalent bonds with oxygen/nitrogen…”
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Sequence Programming with Dynamic Boronic Acid/Catechol Binary Codes by Hebel, Marco, Riegger, Andreas, Zegota, Maksymilian M, Kizilsavas, Gönül, Gačanin, Jasmina, Pieszka, Michaela, Lückerath, Thorsten, Coelho, Jaime A. S, Wagner, Manfred, Gois, Pedro M. P, Ng, David Y. W, Weil, Tanja

“…The development of a synthetic code that enables a sequence programmable feature like DNA represents a key aspect toward intelligent molecular systems. We…”
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A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes) by Santos, Fábio M. F., Rosa, João N., Candeias, Nuno R., Carvalho, Cátia Parente, Matos, Ana I., Ventura, Ana E., Florindo, Helena F., Silva, Liana C., Pischel, Uwe, Gois, Pedro M. P.

“…The modular assembly of boronic acids with Schiff‐base ligands enabled the construction of innovative fluorescent dyes [boronic acid salicylidenehydrazone…”
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Modular Assembly of Reversible Multivalent Cancer‐Cell‐Targeting Drug Conjugates by Santos, Fábio M. F., Matos, Ana I., Ventura, Ana E., Gonçalves, João, Veiros, Luís F., Florindo, Helena F., Gois, Pedro M. P.

“…Herein is described a new modular platform for the construction of cancer‐cell‐targeting drug conjugates. Tripodal boronate complexes featuring reversible…”
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N,O‐Iminoboronates: Reversible Iminoboronates with Improved Stability for Cancer Cells Targeted Delivery by Lopes, Ricardo M. R. M., Ventura, Ana E., Silva, Liana C., Faustino, Hélio, Gois, Pedro M. P.

“…Herein a new class of iminoboronates obtained from 2‐acetylbenzene boronic acids and aminophenols is presented. The N,O‐ligand topology enabled the formation…”
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Cyanine‐Like Boronic Acid‐Derived Salicylidenehydrazone Complexes (Cy‐BASHY) for Bioimaging Applications by Santos, Fábio M. F., Domínguez, Zoe, Fernandes, João P. L., Parente Carvalho, Cátia, Collado, Daniel, Pérez‐Inestrosa, Ezequiel, Pinto, Maria V., Fernandes, Adelaide, Arteaga, Jesús F., Pischel, Uwe, Gois, Pedro M. P.

“…Boronic acid‐derived salicylidenehydrazone complex (BASHY) dyes with a polymethine backbone were designed to yield efficient red‐emitting and two‐photon…”
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Improved thermostable polyvinyl alcohol electrospun nanofibers with entangled naringinase used in a novel mini-packed bed reactor by Nunes, Mário A.P., Martins, Samuel, Rosa, M. Emilia, Gois, Pedro M.P., Fernandes, Pedro C.B., Ribeiro, Maria H.L.

“…Improved NGase–PVA electrospun nanofibers. [Display omitted] •Development of PVA non-crosslinked electrospun nanofibers.•PVA electrospun nanofibers crosslinked…”
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Reversible Lysine Modification on Proteins by Using Functionalized Boronic Acids by Cal, Pedro M. S. D., Frade, Raquel F. M., Cordeiro, Carlos, Gois, Pedro M. P.

“…Iminoboronates have been utilized to successfully install azide and alkyne bioorthogonal functions on proteins, which may then be further reacted with their…”
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Boronic acids as efficient cross linkers for PVA: synthesis and application of tunable hollow microspheres in biocatalysis by Nunes, Mário A.P., Gois, Pedro M.P., Rosa, M. Emilia, Martins, Samuel, Fernandes, Pedro C.B., Ribeiro, Maria H.L.

“…Herein is reported an innovative and reproducible systemic approach for the fabrication of customized 3D hollow microspheres of polyvinyl alcohol (PVA) based…”
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Water as the reaction medium for multicomponent reactions based on boronic acids by Candeias, Nuno R., Cal, Pedro M.S.D., André, Vânia, Duarte, M. Teresa, Veiros, Luís F., Gois, Pedro M.P.

“…Water is a suitable medium for the Petasis-borono-Mannich multicomponent reaction. Salicylaldehyde, glyoxalic acid, glycoaldehyde and glyoxal were reacted with…”
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α-Rhamnosidase and β-glucosidase expressed by naringinase immobilized on new ionic liquid sol–gel matrices: Activity and stability studies by Vila-Real, Helder, Alfaia, António J., Rosa, João N., Gois, Pedro M.P., Rosa, M. Emilia, Calado, António R.T., Ribeiro, Maria H.

“…Novel ionic liquid (IL) sol–gel materials development, for enzyme immobilization, was the goal of this work. The deglycosylation of natural glycosides were…”
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Rhodium-Catalysed Tandem Hydroformylation/Arylation Reaction with Boronic Acids by Almeida, Ana R., Dias, Roberto D., Monteiro, Carlos J. P., Abreu, Artur R., Gois, Pedro M. P., Bayon, J. Carles, Pereira, Mariette M.

“…A new efficient multicatalytic process involving a single catalyst to promote tandem hydroformylation/arylation reactions is disclosed. The effect of the…”
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Intramolecular C–H insertion using NHC–di-rhodium(II) complexes: the influence of axial coordination by Gomes, Luis F.R., Trindade, Alexandre F., Candeias, Nuno R., Gois, Pedro M.P., Afonso, Carlos A.M.

“…NHC axial coordination onto di-rhodium(II) complexes influences the intramolecular C–H insertion process. In this work we show that the intramolecular C–H…”
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Intramolecular C-H insertion catalyzed by dirhodium(II) complexes using CO2 as the reaction media by Zakrzewska, Małgorzata E., Cal, Pedro M.S.D., Candeias, Nuno R., Bogel-Łukasik, Rafał, Afonso, Carlos A.M., Ponte, Manuel N., Gois, Pedro M.P.

“…In this work, the intramolecular C-H insertion of diazoacetamides catalyzed by dirhodium(II) complexes and using CO 2 as solvent is disclosed. The expected…”
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Homologation Reaction of Ketones with Diazo Compounds by Candeias, Nuno R, Paterna, Roberta, Gois, Pedro M. P

“…This review covers the addition of diazo compounds to ketones to afford homologated ketones, either in the presence or in the absence of promoters or…”
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Boronic acids as building blocks for the construction of therapeutically useful bioconjugates by António, João P M, Russo, Roberto, Carvalho, Cátia Parente, Cal, Pedro M S D, Gois, Pedro M P

“…Bioconjugates are multifunctional constructs in which biomolecules like peptides, proteins, vitamins and nucleic acids are endowed with the properties of…”
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