Search Results - "Goins, D. K"

Antigiardial Activity of Isoflavones from Dalbergia frutescens Bark by Khan, I. A, Avery, M. A, Burandt, C. L, Goins, D. K, Mikell, J. R, Nash, T. E, Azadegan, A, Walker, L. A

“…Several isoflavones [formononetin (1), castanin (5), odoratin (6), glycitein (7), pseudobaptogenin (8), fujikinetin (9), and cuneatin (10)] were isolated from…”
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Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 4. Effect of Substitution at C-3 by Avery, Mitchell A, Mehrotra, Sanjiv, Bonk, Jason D, Vroman, Jeffrey A, Goins, D. Keith, Miller, Robert

“…Novel antimalarial artemisinin analogs, 3-alkylartemisinins as well as 3-(arylalkyl)- and 3-(carboxyalkyl)artemisinins, were prepared via the synthetic…”
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A New Quassinoid from Castela texana by Dou, Jinhui, McChesney, James D, Sindelar, Robert D, Goins, D. Keith, Walker, Larry A

“…A new quassinoid, 11-O-trans-p-coumaroyl amarolide (1) was isolated from Castela texana, and the structure was elucidated by spectroscopic analysis. Compound 1…”
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Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 3. Total Synthesis of (+)-13-Carbaartemisinin and Related Tetra- and Tricyclic Structures by Avery, Mitchell A, Fan, Pingchen, Karle, Jean M, Bonk, Jason D, Miller, Robert, Goins, D. Keith

“…Provided by total synthesis, endoperoxides 18, 20, and 22 underwent intramolecular oxymercuration−demercuration leading respectively to formation of an…”
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Structure-Activity Relationships of the Antimalarial Agent Artemisinin. 2. Effect of Heteroatom Substitution at O-11: Synthesis and Bioassay of N-Alkyl-11-aza-9-desmethylartemisinins by Avery, Mitchell A, Bonk, Jason D, Chong, Wesley K. M, Mehrotra, Sanjiv, Miller, Robert, Milhous, Wilbur, Goins, D. Keith, Venkatesan, Sridhar, Wyandt, Christy

“…A novel class of artemisinin analogs, N-alkyl-11-aza-9-desmethylartemisinins 17-29, were synthesized via ozonolysis and acid-catalyzed cyclization of precursor…”
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Synthesis and biological activity of new potential antimalarial: 1H-pyrazolo[3,4-b]pyridine derivatives by Dias, L R, Freitas, A C, Barreiro, E J, Goins, D K, Nanayakkara, D, McChesney, J D, Dias, R S

“…The appearance of drug resistant Plasmodium falciparum malaria necessitates the search for novel antimalarial agents. Using the classical ring-bioisosterism…”
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Tirucallane-type triterpenoids : nmr and X-ray diffraction analyses of 24-epi-piscidinol A and piscidinol A by MCCHESNEY, J. D, DOU, J, SINDELAR, R. D, GOINS, D. K, WALKER, L. A, ROGERS, R. D

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Structure-activity relationship of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-Carbaatemisinin and related tetra -and tricyclic structures by AVERY, M. A, FAN, P, KARLE, J. M, BONK, J. D, MILLER, R, GOINS, D. K

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Structure-activity relationships of the antimalarial agent artemisinin. II: Effect of heteroatom substitution at O-11 : synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins by AVERY, M. A, BONK, J. D, AVERY, B. A, CHONG, W. K. M, SANJIV MEHROTRA, MILLER, R, MILHOUS, W, GOINS, D. K, SRIDHAR VENKATESAN, WYANDT, C, IKHLAS KHAN

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