Search Results - "Goins, Beth"

Novel Multifunctional Theranostic Liposome Drug Delivery System: Construction, Characterization, and Multimodality MR, Near-Infrared Fluorescent, and Nuclear Imaging by Li, Shihong, Goins, Beth, Zhang, Lujun, Bao, Ande

“…Liposomes are effective lipid nanoparticle drug delivery systems, which can also be functionalized with noninvasive multimodality imaging agents with each…”
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Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles by Phillips, William T., Bao, Ande, Brenner, Andrew J., Goins, Beth A.

“…One of the major limitations of current cancer therapy is the inability to deliver tumoricidal agents throughout the entire tumor mass using traditional…”
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Heightened Virulence of Yersinia Is Associated with Decreased Function of the YopJ Protein by Mares, Chris A, Lugo, Fernando P, Albataineh, Mohammad, Goins, Beth A, Newton, Irene G, Isberg, Ralph R, Bergman, Molly A

“…Despite the maintenance of YopP/J alleles throughout the human-pathogenic lineage, the benefit of YopP/J-induced phagocyte death for pathogenesis in animals is…”
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PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure by Taylor, Roslyn A, Xiao, Sixia, Carias, Ann M, McRaven, Michael D, Thakkar, Divya N, Araínga, Mariluz, Allen, Edward J, Rogers, Kenneth A, Kumarapperuma, Sidath C, Gong, Siqi, Fought, Angela J, Anderson, Meegan R, Thomas, Yanique, Schneider, Jeffrey R, Goins, Beth, Fox, Peter, Villinger, Francois J, Ruprecht, Ruth M, Hope, Thomas J

“…Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant…”
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[186 Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model by Soundararajan, Anuradha, Bao, Ande, Phillips, William T, Perez, Ricardo, Goins, Beth A

“…Abstract The purpose of this study was to determine the feasibility of radiolabeling liposomal doxorubicin (Doxil) for cancer chemoradionuclide therapy by…”
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Biodistribution and lymph node retention of polysaccharide-based immunostimulating nanocapsules by Vicente, Sara, Goins, Beth A, Sanchez, Alejandro, Alonso, María J, Phillips, William T

“…Highlights • We studied the biodistribution of PG-nanocapsules using scintigraphic imaging. • We report an efficient method for radiolabeling PG nanocapsules…”
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A colorful approach towards developing new nano-based imaging contrast agents for improved cancer detection by Salinas, Helen R, Miyasato, Dominie L, Eremina, Olga E, Perez, Rodolfo, Gonzalez, Karen L, Czaja, Alexander T, Burkitt, Sean, Aron, Arjun, Fernando, Augusta, Ojeda, Lauro S, Larson, Kimberly N, Mohamed, Ahmed W, Campbell, Jos L, Goins, Beth A, Zavaleta, Cristina

“…Providing physicians with new imaging agents to help detect cancer with better sensitivity and specificity has the potential to significantly improve patient…”
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Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation by Tavakoli, Sina, Downs, Kevin, Short, John, Nguyen, Huynh Nga, Lai, Yanlai, Jerabek, Paul, Goins, Beth, Toczek, Jakub, Sadeghi, Mehran, Asmis, Reto

“…Objective— Despite the early promising results of 18 F-fluorodeoxyglucose positron emission tomography for assessment of vessel wall inflammation, its accuracy…”
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Use of avidin/biotin-liposome system for enhanced peritoneal drug delivery in an ovarian cancer model by Zavaleta, Cristina L., Phillips, William T., Soundararajan, Anuradha, Goins, Beth A.

“…The goal of this study was to determine the distribution of the avidin/biotin-liposome system in an ovarian cancer xenograft model. Optimal…”
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Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow by Mukhopadhyay, Keya De, Bandyopadhyay, Abhik, Chang, Ting-Tung A, Elkahloun, Abdel G, Cornell, John E, Yang, Junhua, Goins, Beth A, Yeh, I-Tien, Sun, Lu-Zhe

“…The origin and the contribution of breast tumor heterogeneity to its progression are not clear. We investigated the effect of a growing orthotopic tumor formed…”
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Ultrasound-guided intratumoral administration of collagenase-2 improved liposome drug accumulation in solid tumor xenografts by Zheng, Xiangpeng, Goins, Beth A, Cameron, Ivan L, Santoyo, Cristina, Bao, Ande, Frohlich, Victoria C, Fullerton, Gary D

“…Purpose To investigate the effect of intratumoral administration of collagenase-2 on liposomal drug accumulation and diffusion in solid tumor xenografts…”
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Selective uptake of surface-modified phospholipid vesicles by bone marrow macrophages in vivo by Sou, Keitaro, Goins, Beth, Takeoka, Shinji, Tsuchida, Eishun, Phillips, William T

“…Abstract An advantage of using vesicles (liposomes) as drug delivery carriers is that their pharmacokinetics can be controlled by surface characteristics,…”
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Interventional Therapy of Head and Neck Cancer with Lipid Nanoparticle–carried Rhenium 186 Radionuclide by French, J. Tyler, MD, Goins, Beth, PhD, Saenz, Marcela, BS, Li, Shihong, PhD, Garcia-Rojas, Xavier, MD, Phillips, William T., MD, Otto, Randal A., MD, Bao, Ande, PhD

“…Purpose Minimally invasive interventional cancer therapy with drug-carrying lipid nanoparticles (ie, liposomes) via convection-enhanced delivery by an infusion…”
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Combination radiofrequency ablation and intravenous radiolabeled liposomal Doxorubicin: imaging and quantification of increased drug delivery to tumors by Head, Hayden W, Dodd, 3rd, Gerald D, Bao, Ande, Soundararajan, Anuradha, Garcia-Rojas, Xavier, Prihoda, Thomas J, McManus, Linda M, Goins, Beth A, Santoyo, Cristina A, Phillips, William T

“…To identify, with noninvasive imaging, the zone of radiopharmaceutical uptake after combination therapy with radiofrequency (RF) ablation and intravenous…”
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Size discrimination in rat and mouse gastric emptying by Jang, Shih-Fan, Goins, Beth A., Phillips, William T., Santoyo, Cristina, Rice-Ficht, Allison, McConville, Jason T.

“…ABSTRACT Objectives To investigate the relationship between particle size and gastric emptying in rodents using radiolabeled insoluble polymethyl methacrylate…”
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Radioactive liposomes by Phillips, William Thomas, Goins, Beth Ann, Bao, Ande

“…Many methods of labeling liposomes with both diagnostic and therapeutic radionuclides have been developed since the initial discovery of liposomes 40 years…”
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Caspase-2 deficiency enhances aging-related traits in mice by Zhang, Yingpei, Padalecki, Susan S., Chaudhuri, Asish R., De Waal, Eric, Goins, Beth A., Grubbs, Barry, Ikeno, Yuji, Richardson, Arlan, Mundy, Gregory R., Herman, Brian

“…Alteration of apoptotic activity has been observed in a number of tissues in aging mammals, but it remains unclear whether and/or how apoptosis may affect…”
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Circulation kinetics and organ distribution of Hb-vesicles developed as a red blood cell substitute by Sou, Keitaro, Klipper, Robert, Goins, Beth, Tsuchida, Eishun, Phillips, William T

“…Phospholipid vesicles encapsulating concentrated human hemoglobin (Hb-vesicles, HbV), also known as liposomes, have a membrane structure similar to that of red…”
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QA procedures for multimodality preclinical tumor drug response testing by Lee, Yongsook C., Goins, Beth A., Fullerton, Gary D.

“…Purpose: There are growing expectations that imaging biomarkers for tumor therapeutic drug response assessment will speed up preclinical testing of anticancer…”
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Construction of a preclinical multimodality phantom using tissue-mimicking materials for quality assurance in tumor size measurement by Lee, Yongsook C, Fullerton, Gary D, Goins, Beth A

“…World Health Organization (WHO) and the Response Evaluation Criteria in Solid Tumors (RECIST) working groups advocated standardized criteria for radiologic…”
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