Search Results - "Goike, H."

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    Mutational Profile of the PTEN Gene in Primary Human Astrocytic Tumors and Cultivated Xenografts by Schmidt, Esther E, Ichimura, Koichi, Goike, Helena M, Moshref, Ahmad, Liu, Lu, Collins, V Peter

    “…The genetic abnormality most frequently identified in glioblastomas is loss of alleles on chromosome 10. We have performed a comprehensive study of the PTEN…”
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    Journal Article
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    Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours by SCHMIDT, E. E, ICHIMURA, K, MESSERLE, K. R, GOIKE, H. M, COLLINS, V. P

    Published in British journal of cancer (1997)
    “…In a series of 46 glioblastomas, 16 anaplastic astrocytomas and eight astrocytomas, all tumours retaining one or both alleles of CDKN2A (48 tumours) and CDKN2B…”
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    Journal Article
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    Newly developed assay measuring cytokeratins 8, 18 and 19 in serum is correlated to survival and tumor volume in patients with esophageal carcinoma by Brattström, D., Wagenius, G., Sandström, P., Dreilich, M., Bergström, S., Goike, H., Hesselius, P., Bergqvist, M.

    Published in Diseases of the esophagus (01-01-2005)
    “…Esophageal carcinoma is the seventh most common cause of cancer‐related death in the Western world. In Sweden, approximately 400 new esophageal carcinomas are…”
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    Journal Article
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    Role of circulating cytokeratin fragments and angiogenic factors in NSCLC patients stage IIIa-IIIb receiving curatively intended treatment by Eriksson, P, Brattström, D, Hesselius, P, Larsson, A, Bergström, S, Ekman, S, Goike, H, Wagenius, G, Brodin, O, Bergqvist, M

    Published in Neoplasma (2006)
    “…Non-small cell lung cancer (NSCLC) is derived from epithelial cells and accounts for approximately 80% of all lung cancers. Cytokeratins are specific for…”
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    Journal Article
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    Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades by Ichimura, Koichi, Schmidt, Esther E., Miyakawa, Ayako, Goike, Helena M., Collins, V. Peter

    Published in Genes chromosomes & cancer (01-05-1998)
    “…Deletions of chromosome 10 are the most frequent genetic abnormality in glioblastomas. Several commonly deleted regions have been proposed; however, they are…”
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    Cryopreservation of viable human glioblastoma xenografts by Goike, H. M., Asplund, A. C., Pettersson, E. H., Liu, L., Ichimura, K., Collins, V. P.

    Published in Neuropathology and applied neurobiology (01-04-2000)
    “…Human tumour xenografts maintained in nude mice are a valuable research tool. The passaging and maintenance of human tumour xenografts in immune‐deficient…”
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    Journal Article
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    Acquired Rearrangement of an Amplified Epidermal Growth Factor Receptor (EGFR) Gene in a Human Glioblastoma Xenograft by Goike, Helena M, Asplund, A.Charlotta, Petersson, E Helene, Liu, L, Sanoudou, D, Collins, V Peter

    “…Amplification of the epidermal growth factor receptor (EGFR) occurs in about 40% of human glioblastomas. In half of these cases, rearrangements of the…”
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    Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities by ICHIMURA, K, BOLIN, M. B, GOIKE, H. M, SCHMIDT, E. E, MOSHREF, A, COLLINS, V. P

    Published in Cancer research (Chicago, Ill.) (15-01-2000)
    “…Deregulation of G1-S transition control in cell cycle is one of the important mechanisms in the development of human tumors including astrocytic gliomas. We…”
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    Journal Article
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    Clinical utility of cytokeratins as tumor markers by Barak, Vivian, Goike, Helena, Panaretakis, Katja W., Einarsson, Roland

    Published in Clinical Biochemistry (01-07-2004)
    “…Cytokeratins, belonging to the intermediate filament (IF) protein family, are particularly useful tools in oncology diagnostics. At present, more than 20…”
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    Book Review Journal Article
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    The Complexity of the 7p12 Amplicon in Human Astrocytic Gliomas: Detailed Mapping of 246 Tumors by LIU, LU, ICHIMURA, KOICHI, PETTERSSON, E HELENA, GOIKE, HELENA M, COLLINS, V PETER

    “…Approximately 30%–35% of human glioblastomas have epidermal growth factor receptor (EGFR) gene amplification. Amplicons containing the EGFR gene frequently…”
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    Tumor markers in breast cancer- European Group on Tumor Markers recommendations by Molina, Rafael, Barak, Vivian, van Dalen, Arie, Duffy, Michael J, Einarsson, Roland, Gion, Massimo, Goike, Helenka, Lamerz, Rolf, Nap, Marius, Sölétormos, György, Stieber, Petra

    Published in Tumor biology (01-01-2005)
    “…Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer…”
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    Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A by FUXE, J, AKUSJÄRVI, G, GOIKE, H. M, ROOS, G, COLLINS, V. P, PETTERSSON, R. F

    Published in Cell growth & differentiation (01-07-2000)
    “…The genes encoding the cyclin-dependent kinase inhibitors p16INK4A (CDKN2A) and p15INK4B (CDKN2B) are frequently homozygously deleted in a variety of tumor…”
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    Journal Article
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