Search Results - "Gohda, Tomohito"
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Sodium-Glucose Cotransporter-2 Inhibitors-Miracle Drugs for the Treatment of Chronic Kidney Disease Irrespective of the Diabetes Status: Lessons from the Dedicated Kidney Disease-Focused CREDENCE and DAPA-CKD Trials
Published in International journal of molecular sciences (09-11-2022)“…Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease worldwide. In Japan, the proportion of new…”
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Circulating Tumor Necrosis Factor Receptors: A Potential Biomarker for the Progression of Diabetic Kidney Disease
Published in International journal of molecular sciences (13-03-2020)“…Despite considerable advancements in medicine, the optimal treatment for chronic kidney disease (CKD), especially diabetic kidney disease (DKD), remains a…”
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Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients
Published in PloS one (11-10-2022)“…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
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Differential organ-specific inflammatory response to progranulin in high-fat diet-fed mice
Published in Scientific reports (13-01-2021)“…Progranulin (PGRN) has been reported to bind tumor necrosis factor (TNF) receptor and to inhibit TNFα signaling. We evaluated the effect of augmentation of…”
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Poor oral hygiene and dental caries predict high mortality rate in hemodialysis: a 3-year cohort study
Published in Scientific reports (14-12-2020)“…The aim of this study was to investigate the impact of oral hygiene, periodontal diseases, and dental caries on all-cause mortality in hemodialysis. This…”
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Preventive dental care reduces risk of cardiovascular disease and pneumonia in hemodialysis population: a nationwide claims database analysis
Published in Scientific reports (29-05-2024)“…This study aims to investigate the impact of dental care utilization status on the occurrence of fatal complications such as cerebral/cardiovascular disease…”
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Circulating TNF Receptors 1 and 2 Predict ESRD in Type 2 Diabetes
Published in Journal of the American Society of Nephrology (01-03-2012)“…Levels of proinflammatory cytokines associate with risk for developing type 2 diabetes but whether chronic inflammation contributes to the development of…”
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Potential Targeting of Renal Fibrosis in Diabetic Kidney Disease Using MicroRNAs
Published in Frontiers in pharmacology (13-11-2020)“…Diabetic kidney disease (DKD) is a major health problem and one of the leading causes of end-stage renal disease worldwide. Despite recent advances, there…”
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Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients
Published in PloS one (11-10-2022)“…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
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Potential of Modulating Aldosterone Signaling and Mineralocorticoid Receptor with microRNAs to Attenuate Diabetic Kidney Disease
Published in International journal of molecular sciences (01-01-2024)“…Diabetic Kidney Disease (DKD) is a significant complication of diabetes and primary cause of end-stage renal disease globally. The exact mechanisms underlying…”
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COVID-19-induced acute renal tubular injury associated with elevation of serum inflammatory cytokine
Published in Clinical and experimental nephrology (01-11-2021)“…Background Severe acute respiratory syndrome Coronavirus 2 has rapidly spread worldwide, with acute kidney injury (AKI) as one of the manifestations with…”
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Circulating TNF Receptors 1 and 2 Predict Stage 3 CKD in Type 1 Diabetes
Published in Journal of the American Society of Nephrology (01-03-2012)“…Elevated plasma concentrations of TNF receptors 1 and 2 (TNFR1 and TNFR2) predict development of ESRD in patients with type 2 diabetes without proteinuria,…”
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Gut Microbiome and Microbiome-Derived Metabolites in Patients with End-Stage Kidney Disease
Published in International journal of molecular sciences (01-07-2023)“…The composition of the gut microbiome is altered in patients with chronic kidney disease (CKD). Dysbiosis leads to decreased levels of stool organic acids…”
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Association between circulating tumor necrosis factor receptors and oral bacterium in patients receiving hemodialysis: a cross-sectional study
Published in Clinical and experimental nephrology (01-01-2021)“…Background High levels of tumor necrosis factor (TNF) receptors (TNFRs; TNFR1 and TNFR2), markers of inflammation, have been reported as significant predictors…”
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Successful Pregnancy and Delivery in a Chronic Renal Failure Patient with Membranoproliferative Glomerulonephritis and Preeclampsia-related Nephrotic Syndrome
Published in Internal Medicine (15-07-2024)“…A 37-year-old woman with chronic kidney disease (CKD) stage G4 with membranoproliferative glomerulonephritis was hospitalized for nephrotic syndrome and…”
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Malnutrition- inflammation- atherosclerosis (MIA) syndrome associates with periodontitis in end-stage renal disease patients undergoing hemodialysis: a cross-sectional study
Published in Scientific reports (21-07-2023)“…Malnutrition-inflammation-atherosclerosis (MIA) syndrome is a significant risk factor for mortality in patients undergoing hemodialysis. This study aimed to…”
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Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy
Published in PloS one (10-04-2015)“…The current study aimed to examine whether the levels of TNF receptors 1 and 2 (TNFR1 and TNFR2) in serum and urine were associated with other markers of…”
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Association of type 2 diabetes with periodontitis and tooth loss in patients undergoing hemodialysis
Published in PloS one (06-05-2022)“…Limited evidence are available regarding the influence of diabetes on periodontitis in hemodialysis patients, although the association between diabetes and…”
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The Prevalence and Management of Diabetic Nephropathy in Asia
Published in Kidney diseases (01-05-2015)“…Background: Diabetic nephropathy (DN), especially type 2 diabetes, is now increasing rapidly worldwide, also in Asian countries, and is one of the major…”
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Circulating TNF receptor levels are associated with estimated glomerular filtration rate even in healthy individuals with normal kidney function
Published in Scientific reports (27-03-2024)“…The association between serum tumor necrosis factor receptor (TNFRs: TNFR1, TNFR2) levels and estimated glomerular filtration rate (eGFR) observed in patients…”
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