Search Results - "Goh, W. S. Sho"

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  1. 1
    Atlas of quantitative single-base-resolution N 6 -methyl-adenine methylomes

    Atlas of quantitative single-base-resolution N 6 -methyl-adenine methylomes by Koh, Casslynn W Q, Goh, Yeek Teck, Goh, W S Sho

    Published in Nature communications (10-12-2019)
    “…Various methyltransferases and demethylases catalyse methylation and demethylation of N -methyladenosine (m6A) and N ,2'-O-dimethyladenosine (m6Am) but precise…”
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  2. 2
    METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing

    METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing by Goh, Yeek Teck, Koh, Casslynn W Q, Sim, Donald Yuhui, Roca, Xavier, Goh, W S Sho

    Published in Nucleic acids research (18-09-2020)
    “…Abstract N 6-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N6,2′-O-dimethyladenosine (m6Am). Identification of the…”
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  3. 3
    Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore

    Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore by Pratanwanich, Ploy N., Yao, Fei, Chen, Ying, Koh, Casslynn W. Q., Wan, Yuk Kei, Hendra, Christopher, Poon, Polly, Goh, Yeek Teck, Yap, Phoebe M. L., Chooi, Jing Yuan, Chng, Wee Joo, Ng, Sarah B., Thiery, Alexandre, Goh, W. S. Sho, Göke, Jonathan

    Published in Nature biotechnology (01-11-2021)
    “…RNA modifications, such as N 6 -methyladenosine (m 6 A), modulate functions of cellular RNA species. However, quantifying differences in RNA modifications has…”
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  4. 4
    Heterogeneity of chemical modifications on RNA

    Heterogeneity of chemical modifications on RNA by Goh, W. S. Sho, Kuang, Yi

    Published in Biophysical reviews (01-02-2024)
    “…The chemical modifications of RNAs broadly impact almost all cellular events and influence various diseases. The rapid advance of sequencing and other…”
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  5. 5
    Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes

    Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes by Koh, Casslynn W. Q., Goh, Yeek Teck, Goh, W. S. Sho

    Published in Nature communications (10-12-2019)
    “…Various methyltransferases and demethylases catalyse methylation and demethylation of N 6 -methyladenosine (m6A) and N 6 ,2′-O-dimethyladenosine (m6Am) but…”
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  6. 6
    Detection of m6A from direct RNA sequencing using a multiple instance learning framework

    Detection of m6A from direct RNA sequencing using a multiple instance learning framework by Hendra, Christopher, Pratanwanich, Ploy N., Wan, Yuk Kei, Goh, W. S. Sho, Thiery, Alexandre, Göke, Jonathan

    Published in Nature methods (01-12-2022)
    “…RNA modifications such as m6A methylation form an additional layer of complexity in the transcriptome. Nanopore direct RNA sequencing can capture this…”
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