Search Results - "Goh, Jia Ni"
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Ex vivo demonstration of canine corneal pre-Descemet’s anatomy using pneumodissection as for the big bubble technique for deep anterior lamellar keratoplasty
Published in Scientific reports (11-04-2023)“…The recent discovery and characterization of pre-Descemet’s layer (PDL; also termed the Dua’s layer or the Dua-Fine layer) has advanced the understanding of…”
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Journal Article -
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The impact of glutaraldehyde based footbaths on Dichelobacter nodosus prevalence and the antimicrobial resistant community of the ovine interdigital skin
Published in Veterinary microbiology (01-09-2022)“…Ovine footrot, is a highly contagious polymicrobial bacterial infection, primarily caused by Dichelobacter nodosus. Preventative bactericidal footbaths are…”
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Application of Static Modeling --in the Prediction of In Vivo Drug-Drug Interactions between Rivaroxaban and Antiarrhythmic Agents Based on In Vitro Inhibition Studies
Published in Drug metabolism and disposition (01-03-2017)“…Rivaroxaban, a direct Factor Xa inhibitor, is indicated for stroke prevention in nonvalvular atrial fibrillation (AF). Studies have revealed that the clearance…”
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Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR
Published in Journal of thrombosis and thrombolysis (01-11-2018)“…The objectives of this study are to compare steady-state trough (Cmin,ss) and peak (Cmax,ss) concentrations of rivaroxaban between Asians and Caucasians and to…”
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Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants
Published in Archives of toxicology (01-09-2021)“…Cytochrome P450 1A1 (CYP1A1) metabolizes estrogens, melatonin, and other key endogenous signaling molecules critical for embryonic/fetal development. The…”
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Pharmacology in the Context of Pathogenic and Non Pathogenic Bacteria
Published 01-01-2023“…Since the invention of the microscope and the discovery of microorganisms, mankind has had a huge fascination with microbes – those that live inside us and…”
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Dissertation -
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Rivaroxaban With and Without Amiodarone in Renal Impairment
Published in Journal of the American College of Cardiology (27-03-2018)“…Simulations of DDIs between rivaroxaban and amiodarone were based on the 2014 American Heart Association/American College of Cardiology/Heart Rhythm Society…”
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Journal Article -
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Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs
Published in The European respiratory journal (01-08-2023)“…Phase 2a trials in tuberculosis typically use early bactericidal activity (EBA), the decline in sputum CFU over 14 days, as the primary end-point for testing…”
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Journal Article