Search Results - "Gogolewski, Krzysztof"
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Revised time estimation of the ancestral human chromosome 2 fusion
Published in BMC genomics (25-08-2022)“…Abstract Background The reduction of the chromosome number from 48 in the Great Apes to 46 in modern humans is thought to result from the end-to-end fusion of…”
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Journal Article -
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Harvest time affects antioxidant capacity, total polyphenol and flavonoid content of Polish St John’s wort’s (Hypericum perforatum L.) flowers
Published in Scientific reports (17-02-2021)“…The polyphenol content and antioxidant capacity of hyperforin and hypericin-standardized H. perforatum L. extracts may vary due to the harvest time. In this…”
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PhaseDancer: a novel targeted assembler of segmental duplications unravels the complexity of the human chromosome 2 fusion going from 48 to 46 chromosomes in hominin evolution
Published in Genome Biology (11-09-2023)“…Abstract Resolving complex genomic regions rich in segmental duplications (SDs) is challenging due to the high error rate of long-read sequencing. Here, we…”
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Low Entropy Sub-Networks Prevent the Integration of Metabolomic and Transcriptomic Data
Published in Entropy (Basel, Switzerland) (31-10-2020)“…The constantly and rapidly increasing amount of the biological data gained from many different high-throughput experiments opens up new possibilities for data-…”
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Journal Article -
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Risk assessment of COVID-19 epidemic resurgence in relation to SARS-CoV-2 variants and vaccination passes
Published in Communications medicine (03-03-2022)“…The introduction of COVID-19 vaccination passes (VPs) by many countries coincided with the Delta variant fast becoming dominant across Europe. A thorough…”
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National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
Published in Communications medicine (31-10-2022)“…Background During the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform…”
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Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression
Published in Biology open (15-11-2016)“…FOXF1 heterozygous point mutations and genomic deletions have been reported in newborns with the neonatally lethal lung developmental disorder, alveolar…”
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TADeus2: a web server facilitating the clinical diagnosis by pathogenicity assessment of structural variations disarranging 3D chromatin structure
Published in Nucleic acids research (05-07-2022)“…Abstract In recent years great progress has been made in identification of structural variants (SV) in the human genome. However, the interpretation of SVs,…”
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Data-driven case fatality rate estimation for the primary lineage of SARS-CoV-2 in Poland
Published in Methods (San Diego, Calif.) (01-07-2022)“…•An average case fatality ratio over the first six months after the outbreak of COVID-19 in Poland was 5.43% (95% CI: 5.08% – 5.73%), while among hospitalized…”
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Inferring Molecular Processes Heterogeneity from Transcriptional Data
Published in BioMed research international (01-01-2017)“…RNA microarrays and RNA-seq are nowadays standard technologies to study the transcriptional activity of cells. Most studies focus on tracking transcriptional…”
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Molecular and clinical analyses of 16q24.1 duplications involving FOXF1 identify an evolutionarily unstable large minisatellite
Published in BMC genetics (04-12-2014)“…Point mutations or genomic deletions of FOXF1 result in a lethal developmental lung disease Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins…”
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PCA-like Methods for the Integration of Single Cell RNA-seq Data with Metabolic Networks
Published in 2018 IEEE 8th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS) (01-10-2018)“…Summary form only. The high-throughput RNA-seq technologies were undeniably a breakthrough step in our understanding of human genome functions. Another,…”
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Conference Proceeding -
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Renal cell carcinoma classification: a case study of pitfalls associated with metabolic landscape analysis
Published in 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01-12-2018)“…The huge amount of biological data gained from many different sources opens up new possibilities alongside with some dangers in data integration. The latter…”
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Conference Proceeding