Search Results - "Gogas, K R"

Central infusion of the melanocortin receptor antagonist agouti-related peptide (AgRP(83-132)) prevents cachexia-related symptoms induced by radiation and colon-26 tumors in mice by Joppa, M.A., Gogas, K.R., Foster, A.C., Markison, S.

“…Cachexia is a clinical wasting syndrome that occurs in multiple disease states, and is associated with anorexia and a progressive loss of body fat and lean…”
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Central administration of peptide and small molecule MC4 receptor antagonists induce hyperphagia in mice and attenuate cytokine-induced anorexia by Joppa, M.A., Ling, N., Chen, C., Gogas, K.R., Foster, A.C., Markison, S.

“…We investigated the effect of melanocortin 4 receptor (MC4) antagonists on food intake in mice. Food intake during the light phase was significantly increased…”
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The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain by Hunter, John C., Gogas, Kathleen R., Hedley, Linda R., Jacobson, Lupita O., Kassotakis, Laura, Thompson, Julie, Fontana, David J.

“…The novel anti-epileptic drugs lamotrigine, felbamate and gabapentin were compared in rat experimental models of acute (tail flick) and chronic pain: the…”
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Glutamate-based therapeutic approaches: NR2B receptor antagonists by Gogas, Kathleen R

“…Over the past decade, there have been major advances in our understanding of the role of glutamate and N-methyl- d-aspartate (NMDA) receptors in several…”
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Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine by Gogas, K R, Cho, H J, Botchkina, G I, Levine, J D, Basbaum, A I

“…In previous studies, we reported that supraspinally administered DAMGO, a mu-opioid agonist, produces a dose-related, naloxone-reversible inhibition of…”
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Walking evokes a distinctive pattern of Fos-like immunoreactivity in the caudal brainstem and spinal cord of the rat by Jasmin, L, Gogas, K R, Ahlgren, S C, Levine, J D, Basbaum, A I

“…We have evaluated the pattern of c-fos expression induced in the rat spinal cord, caudal brainstem and cerebellum by a behavior that is associated with…”
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Morphine or U-50,488 suppresses Fos protein-like immunoreactivity in the spinal cord and nucleus tractus solitarii evoked by a noxious visceral stimulus in the rat by Hammond, D L, Presley, R, Gogas, K R, Basbaum, A I

“…Immunohistochemical visualization of Fos protein, the nuclear phosphoprotein product of the early-immediate gene c-fos, permits identification of populations…”
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Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression by Gogas, K R, Levine, J D, Basbaum, A I

“…In this study, the effect of intracerebroventricular (icv) administration of (5R)-(5 alpha, 7 alpha, 8 beta)-N-methyl-N-[7-(1-pyrrolindinyl)-1-…”
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The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression by Gogas, K R, Presley, R W, Levine, J D, Basbaum, A I

“…In an earlier report, we demonstrated that subcutaneous injection of formalin in the rat hindpaw evokes a characteristic pattern of expression of the fos…”
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Diffuse noxious inhibitory controls reduce the expression of noxious stimulus-evoked Fos-like immunoreactivity in the superficial and deep laminae of the rat spinal cord by Morgan, M M, Gogas, K R, Basbaum, A I

“…Behavioral and electrophysiological studies have shown that a noxious stimulus applied to one part of the body can reduce the response to a subsequent noxious…”
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Distribution of the Tetrodotoxin-Resistant Sodium Channel PN3 in Rat Sensory Neurons in Normal and Neuropathic Conditions by Novakovic, Sanja D, Tzoumaka, Elda, McGivern, Joseph G, Haraguchi, Miki, Sangameswaran, Lakshmi, Gogas, Kathleen R, Eglen, Richard M, Hunter, John C

“…The novel sodium channel PN3/alpha-SNS, which was cloned from a rat dorsal root ganglion (DRG) cDNA library, is expressed predominantly in small sensory…”
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A role for histamine and H2-receptors in opioid antinociception by Gogas, K R, Hough, L B, Eberle, N B, Lyon, R A, Glick, S D, Ward, S J, Young, R C, Parsons, M E

“…To investigate the role of brain H2-receptors in opioid antinociceptive mechanisms, the effects of several antagonists of histamine H2-receptors were…”
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Inhibition of naloxone-resistant antinociception by centrally administered H2-antagonists by Gogas, K R, Hough, L B

“…In order to test directly the hypothesis that brain histamine and H2-receptors mediate the naloxone-resistant footshock-induced antinociception (FSIA) elicited…”
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Effects of zolantidine a brain-penetrating H2-receptor antagonist, on naloxone-sensitive and naloxone-resistant analgesia by Gogas, K R, Hough, L B

“…The action of zolantidine, a histamine H2-receptor antagonist which penetrates the brain, was characterized on the analgesia elicited by brief continuous…”
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Cross-tolerance and cross-sensitization between morphine analgesia and naloxone-sensitive and cimetidine-sensitive stress-induced analgesia by Weinstein, I J, Hough, L B, Gogas, K R

“…Recent studies have shown that different regimens of footshock elicit either "opiate" (naloxone-sensitive) or "histaminergic" (cimetidine-sensitive but…”
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H2-receptor-mediated stress-induced analgesia is dependent on neither pituitary nor adrenal activation by Gogas, K R, Hough, L B

“…The effects of hypophysectomy and adrenalectomy were studied on the analgesia elicited by a 3 min exposure to 3.5 mA of continuous inescapable footshock, a…”
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Opposing actions of cimetidine on naloxone-sensitive and naloxone-insensitive forms of footshock-induced analgesia by Gogas, K R, Hough, L B, Glick, S D, Su, K

“…The effects of the opiate antagonist naloxone (10 mg/kg) and the histamine H2-antagonist cimetidine (100 mg/kg; both administered i.p.) were studied on the…”
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Actions of the brain-penetrating H2-antagonist zolantidine on histamine dynamics and metabolism in rat brain by Hough, L B, Jackowski, S, Eberle, N, Gogas, K R, Camarota, N A, Cue, D

“…The effects of zolantidine, the first brain-penetrating H2-receptor antagonist, on the brain levels of histamine (HA) and the HA metabolite…”
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PN3 sodium channel distribution in the dorsal root ganglia of normal and neuropathic rats by Tzoumaka, E, Novakovic, S D, Haraguchi, M, Sangameswaran, L, Wong, K, Gogas, K R, Hunter, J C

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Mechanisms of opioid-mediated antinociception: correlation of Fos expression and behavior by Gogas, K R, Levine, J D, Basbaum, A I

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