Search Results - "Gogada, Raghu"
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Characterization of high-yield Bacillus subtilis cysteine protease for diverse industrial applications
Published in Brazilian journal of microbiology (01-06-2023)“… Bacterial proteases have extensive applications in various fields of industrial microbiology. In this study, protease-producing organisms were screened on…”
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Resveratrol Induces p53-independent, X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Bax Protein Oligomerization on Mitochondria to Initiate Cytochrome c Release and Caspase Activation
Published in The Journal of biological chemistry (19-08-2011)“…Resveratrol, a naturally occurring phytoalexin, is known to induce apoptosis in multiple cancer cell types, but the underlying molecular mechanisms remain…”
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The MreA Metal-Binding Sites C40, H65, and C69 Play a Critical Role in the Metal Tolerance of Pseudomonas putida KT2440
Published in Current microbiology (01-05-2022)“…Metal-binding proteins occur in the cytosol of most eubacteria. The hypothetical metal responsive protein MreA (PP - 2969 gene; NreA) seems responsible for…”
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Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis
Published in Cell cycle (Georgetown, Tex.) (01-12-2011)“…Previous studies have demonstrated that curcumin induces mitochondria-mediated apoptosis. However, understanding of the molecular mechanisms underlying…”
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Purification and characterization of recombinant FAD synthetase from Neurospora crassa
Published in Biochemistry and biophysics reports (01-12-2021)“…FAD Synthetase (FADS) [EC 2.7.7.2], the second enzyme in flavin cofactor biosynthetic pathway converts FMN to FAD, plays an important role in many redox…”
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Defective molecular timer in the absence of nucleotides leads to inefficient caspase activation
Published in PloS one (27-01-2011)“…In the intrinsic death pathway, cytochrome C (CC) released from mitochondria to the cytosol triggers Apaf-1 apoptosome formation and subsequent caspase…”
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Post-treatment with apocynin at a lower dose regulates the UPR branch of eIF2α and XBP-1 pathways after stroke
Published in Brain research bulletin (01-05-2022)“…Stroke leads to disturbance in the physiology of the ER (Endoplasmic Reticulum) that triggers UPR (Unfolded Protein Response) pathways aimed to compensate…”
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Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2020)“…Cytochrome c (Cyt c) released from mitochondria interacts with Apaf-1 to form the heptameric apoptosome, which initiates the caspase cascade to execute…”
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Engineered Deinococcus radiodurans R1 with NiCoT genes for bioremoval of trace cobalt from spent decontamination solutions of nuclear power reactors
Published in Applied microbiology and biotechnology (01-11-2015)“…The aim of the present work was to engineer bacteria for the removal of Co in contaminated effluents. Radioactive cobalt (⁶⁰Co) is known as a major contributor…”
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Purification and characterization of recombinant FAD synthetase from Neurosporacrassa
Published in Biochemistry and biophysics reports (01-12-2021)“…FAD Synthetase (FADS) [EC 2.7.7.2], the second enzyme in flavin cofactor biosynthetic pathway converts FMN to FAD, plays an important role in many redox…”
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Bim, a Proapoptotic Protein, Up-regulated via Transcription Factor E2F1-dependent Mechanism, Functions as a Prosurvival Molecule in Cancer
Published in The Journal of biological chemistry (04-01-2013)“…Proapoptotic Bcl-2 homology 3-only protein Bim plays an important role in Bax/Bak-mediated cytochrome c release and apoptosis. Here, we provide evidence for a…”
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Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2020)“…Cytochrome c (Cyt c) released from mitochondria interacts with Apaf-1 to form the heptameric apoptosome, which initiates the caspase cascade to execute…”
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13
Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2020)“…Not provided…”
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Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation
Published in Mitochondrion (01-09-2013)“…We recently demonstrated that resveratrol induces caspase-dependent apoptosis in multiple cancer cell types. Whether apoptosis is also regulated by other cell…”
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Neem oil limonoids induces p53-independent apoptosis and autophagy
Published in Carcinogenesis (New York) (01-11-2012)“…Azadirachta indica, commonly known as neem, has a wide range of medicinal properties. Neem extracts and its purified products have been examined for induction…”
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Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation
Published in Free radical biology & medicine (01-01-2016)“…We have previously reported that neem limonoids (neem) induce multiple cancer cell death pathways. Here we dissect the underlying mechanisms of neem-induced…”
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Abstract 1727: Evidence that E2F1-mediated upregulation of Bim, a proapoptotic BH3-only protein, functions as a prosurvival molecule in cancer
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Proapoptotic BH3-only protein Bim plays an important role in Bax/Bak-mediated cytochrome c release and apoptosis. Here we provide evidence for a novel…”
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Evidence that E2F1‐mediated upregulation of Bim, a proapoptotic BH3‐only protein, functions as a prosurvival molecule in cancer
Published in The FASEB journal (01-04-2013)“…Abstract only Proapoptotic BH3‐only protein Bim plays an important role in Bax/Bak‐mediated cytochrome c release and apoptosis. Here we provide evidence for a…”
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