Search Results - "Goffredo, Bianca"

Inhibition of Spinal Oxidative Stress by Bergamot Polyphenolic Fraction Attenuates the Development of Morphine Induced Tolerance and Hyperalgesia in Mice by Lauro, Filomena, Giancotti, Luigino Antonio, Ilari, Sara, Dagostino, Concetta, Gliozzi, Micaela, Morabito, Chiara, Malafoglia, Valentina, Raffaeli, William, Muraca, Maurizio, Goffredo, Bianca M, Mollace, Vincenzo, Muscoli, Carolina

“…Citrus Bergamia Risso, commonly known as Bergamot, is a fruit whose Essential Oil and Bergamot Polyphenolic Fraction have numerous medicinal properties. It is…”
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High-Dose Micafungin in Neonates and Young Infants with Invasive Candidiasis: Results of a Phase 2 Study by Auriti, Cinzia, Goffredo, Bianca M, Ronchetti, Maria P, Piersigilli, Fiammetta, Cairoli, Sara, Bersani, Iliana, Dotta, Andrea, Bagolan, Pietro, Pai, Manjunath P

“…Limited data are available on the most appropriate dosing, efficacy, and safety of micafungin in neonates and young infants with invasive candidiasis (IC)…”
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Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia by Folgiero, Valentina, Goffredo, Bianca M, Filippini, Perla, Masetti, Riccardo, Bonanno, Giuseppina, Caruso, Roberta, Bertaina, Valentina, Mastronuzzi, Angela, Gaspari, Stefania, Zecca, Marco, Torelli, Giovanni F, Testi, Anna M, Pession, Andrea, Locatelli, Franco, Rutella, Sergio

“…Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an…”
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Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes by Del Fattore, Andrea, Luciano, Rosa, Pascucci, Luisa, Goffredo, Bianca Maria, Giorda, Ezio, Scapaticci, Margherita, Fierabracci, Alessandra, Muraca, Maurizio

“…The immunomodulatory activity of mesenchymal stem cells (MSCs) is largely mediated by paracrine factors. We have recently shown that the immunosuppressive…”
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A MALDI-TOF MS Approach for Mammalian, Human, and Formula Milks' Profiling by Di Francesco, Laura, Di Girolamo, Francesco, Mennini, Maurizio, Masotti, Andrea, Salvatori, Guglielmo, Rigon, Giuliano, Signore, Fabrizio, Pietrantoni, Emanuela, Scapaticci, Margherita, Lante, Isabella, Goffredo, Bianca Maria, Mazzina, Oscar, Elbousify, Ahmed Ibrahim, Roncada, Paola, Dotta, Andrea, Fiocchi, Alessandro, Putignani, Lorenza

“…Human milk composition is dynamic, and substitute formulae are intended to mimic its protein content. The purpose of this study was to investigate the…”
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Renal and Extra Renal Manifestations in Adult Zebrafish Model of Cystinosis by Berlingerio, Sante Princiero, He, Junling, De Groef, Lies, Taeter, Harold, Norton, Tomas, Baatsen, Pieter, Cairoli, Sara, Goffredo, Bianca, de Witte, Peter, van den Heuvel, Lambertus, Baelde, Hans J., Levtchenko, Elena

“…Cystinosis is a rare, incurable, autosomal recessive disease caused by mutations in the CTNS gene. This gene encodes the lysosomal cystine transporter…”
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Justification of empiric methodology to determine dexmedetomidine dose for the TREX study by Disma, Nicola, Goffredo, Bianca M., Cairoli, Sara, Cirillo, Ginevra, Morse, James, Anderson, Brian J., Bonfiglio, Rachele, Cordani, Ramona, Garrone, Marco, Patrone, Elisa, Iengo, Annalisa, Bocca, Paola, Izzo, Francesca, Diotto, Veronica, Lenares, Elena, Robino, Chiara, Neri, Simona, Colantonio, Laura, Calderini, Edoardo, Picardo, Sergio, Tucci, Isabella, Di Persio, Alessandra, Montagnini, Luigi, Blesi, Luca, Pistone, Barbara, Kuppers, Beate, De Lorenzo, Brita, Caramelli, Fabio, Pasini, Lorena

“…Introduction Dexmedetomidine is the sedative agent administered in combination with remifentanil and low dose of sevoflurane in the interventional arm of the…”
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Cenobamate as add-on therapy for drug resistant epilepsies: effectiveness, drug to drug interactions and neuropsychological impact. What have we learned from real word evidence? by Pietrafusa, Nicola, Falcicchio, Giovanni, Russo, Emilio, Lattanzi, Simona, Goffredo, Bianca, Simeoli, Raffaele, Cairoli, Sara, Corsetti, Tiziana, Roberti, Roberta, De Tommaso, Marina, Vigevano, Federico, La Neve, Angela, Specchio, Nicola

“…Cenobamate (CNB) is an anti-seizure medication (ASM) approved in 2021 in Europe for adjunctive treatment of focal-onset seizures in adults who were not…”
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Eltrombopag-Induced Acute Liver Failure in a Pediatric Patient: A Pharmacokinetic and Pharmacogenetic Analysis by Marano, Marco, Serafinelli, Jessica, Cairoli, Sara, Martinelli, Diego, Pisani, Mara, Palumbo, Giuseppe, Cefalo, Maria G, Cecchetti, Corrado, Di Nardo, Matteo, Falvella, Felicia S, Goffredo, Bianca M

“…Eltrombopag is an oral thrombopoietin receptor agonist approved for the treatment of patients with chronic idiopathic thrombocytopenic purpura (ITP), who are…”
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Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood‐testis barrier and a subtherapeutic effect of cysteamine in testis by Reda, Ahmed, Veys, Koenraad, Kadam, Prashant, Taranta, Anna, Rega, Laura Rita, Goffredo, Bianca M., Camps, Chelsea, Besouw, Martine, Cyr, Daniel, Albersen, Maarten, Spiessens, Carl, Wever, Liesbeth, Hamer, Robert, Janssen, Mirian C.H., D'Hauwers, Kathleen, Wetzels, Alex, Monnens, Leo, Heuvel, Lambertus, Goossens, Ellen, Levtchenko, Elena

“…Cystinosis is an inherited metabolic disorder caused by autosomal recessive mutations in the CTNS gene leading to lysosomal cystine accumulation. The disease…”
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Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication by Marano, Marco, Goffredo, Bianca M., Pisani, Mara, Filippelli, Sergio, Cecchetti, Corrado, Drago, Fabrizio, Barbieri, Maria A., Nunziata, Joseph, Genuini, Leonardo, Di Nardo, Matteo

“…The use of drugs in suicide attempts is becoming more and more frequent among adolescents. Intentional intoxication with propafenone is very rare and mainly…”
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Cognitive Findings and Behavior in Children and Adolescents with Phenylketonuria by CAPPELLETTI, Simona, COTUGNO, Giovanna, GOFFREDO, Bianca M, NICOLO, Rosanna, BERNABEI, Silvia M, CAVIGLIA, Stefania, DI CIOMMO, Vincenzo

“…The primary aim of this study was to assess cognitive development, in particular that of executive functions (EFs), and behavioral findings for patients with…”
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Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis by Taranta, Anna, Elmonem, Mohamed A, Bellomo, Francesco, De Leo, Ester, Boenzi, Sara, Janssen, Manoe J, Jamalpoor, Amer, Cairoli, Sara, Pastore, Anna, De Stefanis, Cristiano, Colucci, Manuela, Rega, Laura R, Giovannoni, Isabella, Francalanci, Paola, van den Heuvel, Lambertus P, Dionisi-Vici, Carlo, Goffredo, Bianca M, Masereeuw, Rosalinde, Levtchenko, Elena, Emma, Francesco

“…Nephropathic cystinosis is a rare disease caused by mutations of the CTNS gene that encodes for cystinosin, a lysosomal cystine/H+ symporter. The disease is…”
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Impaired phagocytosis in macrophages from patients affected by lysinuric protein intolerance by Barilli, Amelia, Rotoli, Bianca Maria, Visigalli, Rossana, Bussolati, Ovidio, Gazzola, Gian C., Gatti, Rita, Dionisi-Vici, Carlo, Martinelli, Diego, Goffredo, Bianca M., Font-Llitjós, Mariona, Mariani, Francesca, Luisetti, Maurizio, Dall'Asta, Valeria

“…Lysinuric Protein Intolerance (LPI, MIM 222700) is a recessive aminoaciduria caused by defective cationic amino acid transport in epithelial cells of intestine…”
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Therapeutic drug monitoring for meropenem after the extracorporeal membrane oxygenation circuit change in children: is it necessary? by Di Nardo, Matteo, Cairoli, Sara, Goffredo, Bianca M, Stoppa, Francesca, D'Argenio, Patrizia, Corsetti, Tiziana, Ranieri, Vito M

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Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine by Martinelli, Diego, Häberle, Johannes, Rubio, Vicente, Giunta, Cecilia, Hausser, Ingrid, Carrozzo, Rosalba, Gougeard, Nadine, Marco-Marín, Clara, Goffredo, Bianca M., Meschini, Maria Chiara, Bevivino, Elsa, Boenzi, Sara, Colafati, Giovanna Stefania, Brancati, Francesco, Baumgartner, Matthias R., Dionisi-Vici, Carlo

“…Δ 1 -Pyrroline-5-carboxylate synthetase (P5CS) catalyzes the first two steps of ornithine/proline biosynthesis. P5CS deficiency has been reported in three…”
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Therapeutic Drug Monitoring Is a Feasible Tool to Personalize Drug Administration in Neonates Using New Techniques: An Overview on the Pharmacokinetics and Pharmacodynamics in Neonatal Age by De Rose, Domenico Umberto, Cairoli, Sara, Dionisi, Marco, Santisi, Alessandra, Massenzi, Luca, Goffredo, Bianca Maria, Dionisi-Vici, Carlo, Dotta, Andrea, Auriti, Cinzia

“…Therapeutic drug monitoring (TDM) should be adopted in all neonatal intensive care units (NICUs), where the most preterm and fragile babies are hospitalized…”
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Long-term effects of luteolin in a mouse model of nephropathic cystinosis by De Leo, Ester, Taranta, Anna, Raso, Roberto, Pezzullo, Marco, Piccione, Michela, Matteo, Valentina, Vitale, Alessia, Bellomo, Francesco, Goffredo, Bianca Maria, Diomedi Camassei, Francesca, Prencipe, Giusi, Rega, Laura Rita, Emma, Francesco

“…In infantile nephropathic cystinosis, variants of the CTNS gene cause accumulation of cystine in lysosomes, causing progressive damage to most organs. Patients…”
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Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module by Di Magno, Laura, Manni, Simona, Di Pastena, Fiorella, Coni, Sonia, Macone, Alberto, Cairoli, Sara, Sambucci, Manolo, Infante, Paola, Moretti, Marta, Petroni, Marialaura, Nicoletti, Carmine, Capalbo, Carlo, De Smaele, Enrico, Di Marcotullio, Lucia, Giannini, Giuseppe, Battistini, Luca, Goffredo, Bianca Maria, Iorio, Egidio, Agostinelli, Enzo, Maroder, Marella, Canettieri, Gianluca

“…The antidiabetic drug phenformin displays potent anticancer activity in different tumors, but its mechanism of action remains elusive. Using Shh…”
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Father-to-daughter transmission in late-onset OTC deficiency: an underestimated mechanism of inheritance of an X-linked disease by Siri, Barbara, Olivieri, Giorgia, Lepri, Francesca Romana, Poms, Martin, Goffredo, Bianca Maria, Commone, Anna, Novelli, Antonio, Häberle, Johannes, Dionisi-Vici, Carlo

“…Ornithine Transcarbamylase Deficiency (OTCD) is an X-linked urea cycle disorder characterized by acute hyperammonemic episodes. Hemizygous males are usually…”
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