Search Results - "Goffinet, A M"

Neural progenitor fate decision defects, cortical hypoplasia and behavioral impairment in Celsr1-deficient mice by Boucherie, C, Boutin, C, Jossin, Y, Schakman, O, Goffinet, A M, Ris, L, Gailly, P, Tissir, F

“…The development of the cerebral cortex is a tightly regulated process that relies on exquisitely coordinated actions of intrinsic and extrinsic cues. Here, we…”
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Reelin receptors in developing laminated brain structures of mouse and human by Perez-Garcia, C. G., Tissir, F., Goffinet, A. M, Meyer, G.

“…Reelin is an extracellular matrix protein secreted by a variety of cell types throughout the developing brain. The target cells for reelin express the…”
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Reelin mRNA Expression During Mouse Brain Development by Schiffmann, S. N., Bernier, B., Goffinet, A. M.

“…Using in situ hybridization, expression of the mRNA for reelin, the gene most probably responsible for the reeler trait, was studied during mouse brain…”
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A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant mice by de Bergeyck, V, Naerhuyzen, B, Goffinet, A.M, Lambert de Rouvroit, C

“…Reelin, the extracellular matrix protein defective in reeler mutant mice, plays a key role during brain development. We therefore raised antibodies directed…”
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Reelin and brain development by Goffinet, André M, Tissir, Fadel

“…Over the last 50 years, the reeler mutant mouse has become an important model for studying normal and abnormal development in the cerebral cortex and other…”
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Reelin, the Extracellular Matrix Protein Deficient in Reeler Mutant Mice, Is Processed by a Metalloproteinase by Lambert de Rouvroit, Catherine, de Bergeyck, Vinciane, Cortvrindt, Caroline, Bar, Isabelle, Eeckhout, Yves, Goffinet, André M.

“…Reelin is the extracellular protein defective in reeler mice. It is believed that reelin acts via the extracellular matrix to influence the development of…”
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Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice by Qu, Yibo, Glasco, Derrick M, Zhou, Libing, Sawant, Anagha, Ravni, Aurélia, Fritzsch, Bernd, Damrau, Christine, Murdoch, Jennifer N, Evans, Sylvia, Pfaff, Samuel L, Formstone, Caroline, Goffinet, André M, Chandrasekhar, Anand, Tissir, Fadel

“…During hindbrain development, facial branchiomotor neurons (FBM neurons) migrate from medial rhombomere (r) 4 to lateral r6. In zebrafish, mutations in planar…”
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Reelin expression during embryonic brain development in Crocodylus niloticus by Tissir, F., Lambert De Rouvroit, C., Sire, J.-Y., Meyer, G., Goffinet, A.M.

“…The expression of reelin mRNA and protein was studied during embryonic brain development in the Nile crocodile Crocodylus niloticus, using in situ…”
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Reelin Does Not Directly Influence Axonal Growth by Jossin, Yves, Goffinet, Andre M

“…Reelin is a large extracellular glycoprotein involved in the development of architectonic patterns, particularly in the cerebral cortex and hippocampus, where…”
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Abnormalities in the cerebellum and brainstem in homozygous lurcher mice by Resibois, A, Cuvelier, L, Goffinet, A.M

“…The lurcher mutation induces Purkinje cell degeneration in heterozygous mice, and neonatal death in homozygous animals. Using the D6Mit16 Simple Sequence…”
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A new view of early cortical development by Lambert de Rouvroit, Catherine, Goffinet, André M.

“…Recently, several genes that regulate the development of the cerebral cortex and are potential pharmacological targets have been cloned. Reelin, an…”
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Maturation of "neocortex isole" in vivo in mice by Zhou, Libing, Gall, David, Qu, Yibo, Prigogine, Cynthia, Cheron, Guy, Tissir, Fadel, Schiffmann, Serge N, Goffinet, Andre M

“…How much neocortical development depends on connections remains elusive. Here, we show that Celsr3|Dlx mutant mice have no extrinsic neocortical connections…”
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Reelin mRNA expression during embryonic brain development in the turtle Emys orbicularis by Bernier, B., Bar, I., Pieau, C., Lambert De Rouvroit, C., Goffinet, A.M.

“…The expression of reelin messenger ribonucleic acid (mRNA) was studied during embryonic brain development in the turtle Emys orbicularis, by using radioactive…”
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The role of reelin in the development and evolution of the cerebral cortex by Tissir, F, Lambert de Rouvroit, C, Goffinet, A M

“…Reelin is an extracellular matrix protein that is defective in reeler mutant mice and plays a key role in the organization of architectonic patterns,…”
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Role of the Atypical Cadherin Celsr3 during Development of the Internal Capsule by Zhou, Libing, Qu, Yibo, Tissir, Fadel, Goffinet, Andre M.

“…The development of axonal tracts requires interactions between growth cones and the environment. Major bundles, particularly in the internal capsule, are…”
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A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments by Bar, I., De Rouvroit, C.Lambert, Royaux, I., Krizman, D.B., Dernoncourt, C., Ruelle, D., Beckers, M.C., Goffinet, A.M.

“…The reeler mutation in the mouse maps to proximal chromosome 5 and defines a key gene involved in brain development and evolution. No gene product is known,…”
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Glucose utilization in human visual cortex is abnormally elevated in blindness of early onset but decreased in blindness of late onset by Veraart, C, De Volder, A G, Wanet-Defalque, M C, Bol, A, Michel, C, Goffinet, A M

“…Glucose utilization has been studied in the visual cortex of blind human subjects, by comparison with normal volunteers, using positron emission tomography. In…”
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A truncated Reelin protein is produced but not secreted in the ‘Orleans’ reeler mutation ( Reln rl-Orl ) by de Bergeyck, V., Nakajima, K., de Rouvroit, C. Lambert, Naerhuyzen, B., Goffinet, A.M., Miyata, T., Ogawa, M., Mikoshiba, K.

“…Reelin is the protein defective in reeler mutant mice [I. Bar, C. Lambert de Rouvroit, I. Royaux, D.B. Krizman, C. Dernoncourt, D. Ruelle, M.C. Beckers, A.M…”
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The Central Fragment of Reelin, Generated by Proteolytic Processing In Vivo, Is Critical to Its Function during Cortical Plate Development by Jossin, Yves, Ignatova, Nina, Hiesberger, Thomas, Herz, Joachim, Lambert de Rouvroit, Catherine, Goffinet, Andre M

“…Reelin is a large extracellular protein that controls cortical development. It binds to lipoprotein receptors very-low-density lipoprotein receptor and…”
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Genomic organization of the mouse reelin gene by ROYAUX, I, LAMBERT DE ROUVROIT, C, D'ARCANGELO, G, DEMIROV, D, GOFFINET, A. M

“…Reelin is the protein defective in reeler mice, an extensively studied model of brain development. The reelin gene (symbol Reln) codes for a protein of the…”
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