Search Results - "Goff, W."

Fatal hepatic necrosis after nivolumab as a bridge to liver transplant for HCC: Are checkpoint inhibitors safe for the pretransplant patient? by Nordness, Mina F., Hamel, Stephanie, Godfrey, Caroline M., Shi, Chanjuan, Johnson, Douglas B., Goff, Laura W., O’Dell, Heather, Perri, Roman E., Alexopoulos, Sophoclis P.

“…Nivolumab is an immune checkpoint inhibitor (ICI) currently in phase 3 clinical trials for hepatocellular carcinoma. The safety of ICIs in recipients of organ…”
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Aurora kinase inhibitors--rising stars in cancer therapeutics? by Dar, Altaf A, Goff, Laura W, Majid, Shahana, Berlin, Jordan, El-Rifai, Wael

“…Standard therapeutic approaches of cytotoxics and radiation in cancer are not only highly toxic, but also of limited efficacy in treatment of a significant…”
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Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure by Flamant, M., Mougenot, N., Balse, E., Le Fèvre, L., Atassi, F., Gautier, E. L., Le Goff, W., Keck, M., Nadaud, S., Combadière, C., Boissonnas, A., Pavoine, C.

“…We recently highlighted a novel potential protective paracrine role of cardiac myeloid CD11b/c cells improving resistance of adult hypertrophied cardiomyocytes…”
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Immunotherapy in Biliary Tract Cancers: Current Standard-of-Care and Emerging Strategies by Lo, Justin H, Agarwal, Rajiv, Goff, Laura W, Heumann, Thatcher R

“…Biliary tract cancers (BTCs), comprising intrahepatic, perihilar, and distal cholangiocarcinoma as well as gallbladder adenocarcinoma, continue to be…”
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Physiopathology of necrobiotic xanthogranuloma with monoclonal gammopathy by Szalat, R., Pirault, J., Fermand, J.‐P., Carrié, A., Saint‐Charles, F., Olivier, M., Robillard, P., Frisdal, E., Villard, E. F., Cathébras, P., Bruckert, E., Chapman, M. John, Giral, P., Guerin, M., Lesnik, P., Goff, W. Le

“…Rationale Xanthomatosis associated with monoclonal gammopathy includes hyperlipidaemic xanthoma (HX), normolipidaemic xanthoma (NX) and necrobiotic…”
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The intermediate polar cataclysmic variable GK Persei 120 years after the nova explosion: a first dynamical mass study by Álvarez-Hernández, A, Torres, M A P, Rodríguez-Gil, P, Shahbaz, T, Anupama, G C, Gazeas, K D, Pavana, M, Raj, A, Hakala, P, Stone, G, Gomez, S, Jonker, P G, Ren, J-J, Cannizzaro, G, Pastor-Marazuela, I, Goff, W, Corral-Santana, J M, Sabo, R

“…ABSTRACT We present a dynamical study of the intermediate polar and dwarf nova cataclysmic variable GK Persei (Nova Persei 1901) based on a multisite optical…”
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Phase II Study of the Mitogen-Activated Protein Kinase 1/2 Inhibitor Selumetinib in Patients With Advanced Hepatocellular Carcinoma by O'NEIL, Bert H, GOFF, Laura W, SEBTI, Said M, SULLIVAN, Daniel M, WOOK KAUH, John Sae, STROSBERG, Jonathan R, BEKAII-SAAB, Tanios S, LEE, Ruey-Min, KAZI, Aslamuzzaman, MOORE, Dominic T, LEAROYD, Maria, LUSH, Richard M

“…PURPOSE Hepatocellular carcinoma (HCC) is a common and deadly malignancy with few systemic therapy options. The RAF/mitogen-activated protein kinase kinase…”
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Enabling a Genetically Informed Approach to Cancer Medicine: A Retrospective Evaluation of the Impact of Comprehensive Tumor Profiling Using a Targeted Next‐Generation Sequencing Panel by Johnson, Douglas B., Dahlman, Kimberly H., Knol, Jared, Gilbert, Jill, Puzanov, Igor, Means‐Powell, Julie, Balko, Justin M., Lovly, Christine M., Murphy, Barbara A., Goff, Laura W., Abramson, Vandana G., Crispens, Marta A., Mayer, Ingrid A., Berlin, Jordan D., Horn, Leora, Keedy, Vicki L., Reddy, Nishitha M., Arteaga, Carlos L., Sosman, Jeffrey A., Pao, William

“…Background. Oncogenic genetic alterations “drive” neoplastic cell proliferation. Small molecule inhibitors and antibodies are being developed that target an…”
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Hyper-dilute botulinum toxin as an effective treatment for refractory erythromelalgia by Brown, Ariel, AbdelHameid, Duaa, Nezafati, Kaveh, Goff, Heather W.

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The dual role for probiotics use in dental practices by Goff, Debra A, McFarland, Lynne V, Johnson, Stuart, Goff, Douglas W

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Chronic lymphocytic leukemia skin infiltrates presenting as eyebrow alopecia and erythematous pruritic papules refractory to treatment with topical steroids by Zhu, Jane L., Goff, Heather W.

“…We describe a patient who presented with erythematous papules and hair loss solely limited to the eyebrows. Clinicians should be aware of this presentation of…”
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Current Progress in Immunotherapy for the Treatment of Biliary Cancers by Pauff, James M., Goff, Laura W.

“…Purpose Biliary tract cancers (BTC) remain one of the poorest groups of malignancies in terms of long-term survival, with only limited success in improvements…”
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The helium-rich cataclysmic variable SBSS 1108+574 by Carter, P. J., Steeghs, D., de Miguel, E., Goff, W., Koff, R. A., Krajci, T., Marsh, T. R., Gänsicke, B. T., Breedt, E., Groot, P. J., Nelemans, G., Roelofs, G. H. A., Rau, A., Koester, D., Kupfer, T.

“…We present time-resolved spectroscopy and photometry of the dwarf nova SBSS 1108+574, obtained during the 2012 outburst. Its quiescent spectrum is unusually…”
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Accretion-disc precession in UX Ursae Majoris by de Miguel, E, Patterson, J, Cejudo, D, Ulowetz, J, Jones, J L, Boardman, J, Barret, D, Koff, R, Stein, W, Campbell, T, Vanmunster, T, Menzies, K, Slauson, D, Goff, W, Roberts, G, Morelle, E, Dvorak, S, Hambsch, F-J, Starkey, D, Collins, D, Costello, M, Cook, M J, Oksanen, A, Lemay, D, Cook, L M, Ogmen, Y, Richmond, M, Kemp, J

“…We report the results of a long campaign of time series photometry on the nova-like variable UX Ursae Majoris during 2015. It spanned 150 nights, with ~ 1800 h…”
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Pecan cultivar evaluations by Auburn University by Goff, W. D

“…Auburn University has replicated pecan (Carya illinoinensis [Wangenh.] K. Koch) cultivar evaluations at five locations, four in Alabama and one in Georgia…”
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A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process by Thibord, Florian, Hardy, Lise, Ibrahim‐Kosta, Manal, Saut, Noémie, Pulcrano‐Nicolas, Anne‐Sophie, Goumidi, Louisa, Civelek, Mete, Eriksson, Per, Deleuze, Jean‐François, Le Goff, Wilfried, Trégouët, David‐Alexandre, Morange, Pierre‐Emmanuel

“…Background Factor V (FV) is a circulating protein primarily synthesized in the liver, and mainly present in plasma. It is a major component of the coagulation…”
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Modelling Ebola within a community by LEANDER, R. N., GOFF, W. S., MURPHY, C. W., PULIDO, S. A.

“…The 2014 Ebola epidemic was the largest on record. It evidenced the need for improved models of the spread of Ebola. In this research we focus on modelling…”
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Current Therapy and Future Directions in Biliary Tract Malignancies by Ciombor, Kristen K., Goff, Laura W.

“…Opinion Statement Cancers of the biliary tree represent a rare group of diseases with a devastating impact on patients. Gallbladder cancer often is associated…”
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Reduction in plasma cholesterol efflux capacity from human macrophages is associated with the appearance of clinical features of metabolic syndrome by Gall, J, Frisdal, E, Bittar, R, Le Goff, W, Bruckert, E, Lesnik, P, Guerin, M, Giral, P

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The Insulin-like Growth Factor Signaling Pathway as a Target for Treatment of Colorectal Carcinoma by Ewing, Gideon P, Goff, Laura W

“…Abstract The insulin-like growth factors (IGFs), IGF1 and IGF2, are peptide hormones that bind to the insulin-like growth factor 1 receptor (IGF1R) and cause…”
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