Search Results - "Goff, C."

Validation of the Atherosclerotic Cardiovascular Disease Pooled Cohort Risk Equations by Muntner, Paul, Colantonio, Lisandro D, Cushman, Mary, Goff, David C, Howard, George, Howard, Virginia J, Kissela, Brett, Levitan, Emily B, Lloyd-Jones, Donald M, Safford, Monika M

“…IMPORTANCE The American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort risk equations were developed to estimate atherosclerotic…”
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Utility of Nontraditional Risk Markers in Atherosclerotic Cardiovascular Disease Risk Assessment by Yeboah, Joseph, MD, MS, Young, Rebekah, PhD, McClelland, Robyn L., PhD, Delaney, Joseph C., PhD, Polonsky, Tamar S., MD, MSci, Dawood, Farah Z., MD, MS, Blaha, Michael J., MD, MPH, Miedema, Michael D., MD, MPH, Sibley, Christopher T., MD, Carr, J. Jeffrey, MD, MSc, Burke, Gregory L., MD, MS, Goff, David C., MD, PhD, Psaty, Bruce M., MD, PhD, Greenland, Philip, MD, Herrington, David M., MD, MHS

“…Abstract Background The improvement in discrimination gained by adding nontraditional cardiovascular risk markers cited in the 2013 American College of…”
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The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophrenia by Cohen, Samuel M, Tsien, Richard W, Goff, Donald C, Halassa, Michael M

“…Abstract While the dopamine hypothesis has dominated schizophrenia research for several decades, more recent studies have highlighted the role of fast synaptic…”
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The Long-Term Effects of Antipsychotic Medication on Clinical Course in Schizophrenia by Goff, Donald C, Falkai, Peter, Fleischhacker, W. Wolfgang, Girgis, Ragy R, Kahn, Rene M, Uchida, Hiroyuki, Zhao, Jingping, Lieberman, Jeffrey A

“…Concerns have been raised that treatment with antipsychotic medication might adversely affect long-term outcomes for people with schizophrenia. The evidence…”
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Epidemiologic Relationships Between A1C and All-Cause Mortality During a Median 3.4-Year Follow-up of Glycemic Treatment in the ACCORD Trial by RIDDLE, MatthewC, AMBROSIUS, Walter T, SCHNALL, Adrian, SEAQUIST, Elizabeth R, BRILLON, David J, BUSE, John B, BYINGTON, Robert P, COHEN, Robert M, GOFF, David C, MALOZOWSKI, Saul, MARGOLIS, Karen L, PROBSTFIELD, Jeffrey L

“…Randomized treatment comparing an intensive glycemic treatment strategy with a standard strategy in the Action to Control Cardiovascular Risk in Diabetes…”
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Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data by Karmali, Kunal N, Lloyd-Jones, Donald M, van der Leeuw, Joep, Goff, Jr, David C, Yusuf, Salim, Zanchetti, Alberto, Glasziou, Paul, Jackson, Rodney, Woodward, Mark, Rodgers, Anthony, Neal, Bruce C, Berge, Eivind, Teo, Koon, Davis, Barry R, Chalmers, John, Pepine, Carl, Rahimi, Kazem, Sundström, Johan

“…Clinical practice guidelines have traditionally recommended blood pressure treatment based primarily on blood pressure thresholds. In contrast, using predicted…”
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Ethnic Distribution of ECG Predictors of Atrial Fibrillation and Its Impact on Understanding the Ethnic Distribution of Ischemic Stroke in the Atherosclerosis Risk in Communities (ARIC) Study by SOLIMAN, Elsayed Z, PRINEAS, Ronald J, CASE, L. Douglas, ZHANG, Zhu-Ming, GOFF, David C

“…The paradox of the reported low prevalence of atrial fibrillation (AF) in blacks compared with whites despite higher stroke rates in the former could be…”
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The treatment of cognitive impairment in schizophrenia by Goff, Donald C., Hill, Michele, Barch, Deanna

“…Cognitive deficits are major contributors to disability in schizophrenia. Many pharmacologic targets have been identified for cognitive enhancing agents,…”
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Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age by Allen, Norrina B, Siddique, Juned, Wilkins, John T, Shay, Christina, Lewis, Cora E, Goff, David C, Jacobs, David R, Liu, Kiang, Lloyd-Jones, Donald

“…IMPORTANCE Single measures of blood pressure (BP) levels are associated with the development of atherosclerosis; however, long-term patterns in BP and their…”
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A Systematic Examination of the 2013 ACC/AHA Pooled Cohort Risk Assessment Tool for Atherosclerotic Cardiovascular Disease by Karmali, Kunal N., MD, Goff, David C., MD, PhD, Ning, Hongyan, MD, Lloyd-Jones, Donald M., MD, ScM

“…Abstract Background The 2013 American College of Cardiology/American Heart Association updated cholesterol guidelines recommend the use of Pooled Cohort…”
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The Emerging Role of Glutamate in the Pathophysiology and Treatment of Schizophrenia by Goff, Donald C., Coyle, Joseph T.

“…OBJECTIVE: Research has implicated dysfunction of glutamatergic neurotransmission in the pathophysiology of schizophrenia. This review evaluates evidence from…”
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The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT) by Ambrosius, Walter T, Sink, Kaycee M, Foy, Capri G, Berlowitz, Dan R, Cheung, Alfred K, Cushman, William C, Fine, Lawrence J, Goff, David C, Johnson, Karen C, Killeen, Anthony A, Lewis, Cora E, Oparil, Suzanne, Reboussin, David M, Rocco, Michael V, Snyder, Joni K, Williamson, Jeff D, Wright, Jackson T, Whelton, Paul K

“…Background: High blood pressure is an important public health concern because it is highly prevalent and a risk factor for adverse health outcomes, including…”
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Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Disease Risk in Adults: Synopsis of the 2013 American College of Cardiology/American Heart Association Cholesterol Guideline by STONE, Neil J, ROBINSON, Jennifer G, LICHTENSTEIN, Alice H, GOFF, David C, LLOYD-JONES, Donald M, SMITH, Sidney C, BLUM, Conrad, SCHWARTZ, J. Sanford

“…In November 2013, the American College of Cardiology and American Heart Association (ACC/AHA) released a clinical practice guideline on the treatment of blood…”
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Outcomes of Combined Cardiovascular Risk Factor Management Strategies in Type 2 Diabetes: The ACCORD Randomized Trial by MARGOLIS, Karen L, O'CONNOR, Patrick J, LIPKIN, Edward W, NARAYAN, K. M. Venkat, RIDDLE, Matthew C, SOOD, Ajay, GOFF, David C, MORGAN, Timothy M, BUSE, John B, COHEN, Robert M, CUSHMAN, William C, CUTLER, Jeffrey A, EVANS, Gregory W, GERSTEIN, Hertzel C, GRIMM, Richard H

“…To compare effects of combinations of standard and intensive treatment of glycemia and either blood pressure (BP) or lipids in the Action to Control…”
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Estimating Longitudinal Risks and Benefits From Cardiovascular Preventive Therapies Among Medicare Patients: The Million Hearts Longitudinal ASCVD Risk Assessment Tool: A Special Report From the American Heart Association and American College of Cardiology by Lloyd-Jones, Donald M, Huffman, Mark D, Karmali, Kunal N, Sanghavi, Darshak M, Wright, Janet S, Pelser, Colleen, Gulati, Martha, Masoudi, Frederick A, Goff, David C

“…The Million Hearts Initiative has a goal of preventing 1 million heart attacks and strokes—the leading causes of mortality—through several public health and…”
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D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity by Goff, Donald C

“…Background: Dysregulation of N-methyl D-aspartate (NMDA) receptor signaling is strongly implicated in schizophrenia. Based on the ketamine model of NMDA…”
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Coronary Artery Calcium to Guide a Personalized Risk-Based Approach to Initiation and Intensification of Antihypertensive Therapy by McEvoy, John W., Martin, Seth S., Dardari, Zeina A., Miedema, Michael D., Sandfort, Veit, Yeboah, Joseph, Budoff, Matthew J., Goff, David C., Psaty, Bruce M., Post, Wendy S., Nasir, Khurram, Blumenthal, Roger S., Blaha, Michael J.

“…BACKGROUND:The use of atherosclerotic cardiovascular disease (ASCVD) risk to personalize systolic blood pressure (SBP) treatment goals is a topic of increasing…”
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Impact of Frequent and Unrecognized Hypoglycemia on Mortality in the ACCORD Study by Seaquist, Elizabeth R, Miller, Michael E, Bonds, Denise E, Feinglos, Mark, Goff, David C., Jr, Peterson, Kevin, Senior, Peter

“…OBJECTIVE: The aim of this study was to examine the relationship between frequent and unrecognized hypoglycemia and mortality in the Action to Control…”
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Clinical implications of discordance between low-density lipoprotein cholesterol and particle number by Otvos, James D., PhD, Mora, Samia, MD, MHS, Shalaurova, Irina, MD, Greenland, Philip, MD, Mackey, Rachel H., PhD, MPH, Goff, David C., MD, PhD

“…Background The amount of cholesterol per low-density lipoprotein (LDL) particle is variable and related in part to particle size, with smaller particles…”
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Atrial fibrillation incidence and risk factors in relation to race-ethnicity and the population attributable fraction of atrial fibrillation risk factors: the Multi-Ethnic Study of Atherosclerosis by Rodriguez, Carlos J., MD, MPH, Soliman, Elsayed Z., MD, MSc, Alonso, Alvaro, MD, PhD, Swett, Katrina, MS, Okin, Peter M., MD, Goff, David C., MD, PhD, Heckbert, Susan R., MD, PhD

“…Abstract Purpose We studied incident atrial fibrillation (AF) in the prospective community-based Multi-Ethnic Study of Atherosclerosis (MESA). Reportedly,…”
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