Search Results - "Goetz, Jacky"

Mechanical Adaptability of Tumor Cells in Metastasis by Gensbittel, Valentin, Kräter, Martin, Harlepp, Sébastien, Busnelli, Ignacio, Guck, Jochen, Goetz, Jacky G.

“…The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will successfully form life-threatening metastases when they undergo sequential…”
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Fluids and their mechanics in tumour transit: shaping metastasis by Follain, Gautier, Herrmann, David, Harlepp, Sébastien, Hyenne, Vincent, Osmani, Naël, Warren, Sean C., Timpson, Paul, Goetz, Jacky G.

“…Metastasis is a dynamic succession of events involving the dissemination of tumour cells to distant sites within the body, ultimately reducing the survival of…”
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Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo by Verweij, Frederik J., Revenu, Celine, Arras, Guillaume, Dingli, Florent, Loew, Damarys, Pegtel, D. Michiel, Follain, Gautier, Allio, Guillaume, Goetz, Jacky G., Zimmermann, Pascale, Herbomel, Philippe, Del Bene, Filippo, Raposo, Graça, van Niel, Guillaume

“…Extracellular vesicles (EVs) are released by most cell types but providing evidence for their physiological relevance remains challenging due to a lack of…”
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Extravasation of immune and tumor cells from an endothelial perspective by Dupas, Amandine, Goetz, Jacky G., Osmani, Naël

“…ABSTRACT Crossing the vascular endothelium is a necessary stage for circulating cells aiming to reach distant organs. Leukocyte passage through the…”
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Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis by Goetz, Jacky G., Minguet, Susana, Navarro-Lérida, Inmaculada, Lazcano, Juan José, Samaniego, Rafael, Calvo, Enrique, Tello, Marta, Osteso-Ibáñez, Teresa, Pellinen, Teijo, Echarri, Asier, Cerezo, Ana, Klein-Szanto, Andres J.P., Garcia, Ricardo, Keely, Patricia J., Sánchez-Mateos, Paloma, Cukierman, Edna, Del Pozo, Miguel A.

“…Mechanotransduction is a key determinant of tissue homeostasis and tumor progression. It is driven by intercellular adhesions, cell contractility, and forces…”
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Metastases go with the flow by Goetz, Jacky G

“…Blood flow mechanics influence metastatic efficiency To colonize distant organs and thus disseminate throughout the body, cancer cells and associated factors…”
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Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo by Hyenne, Vincent, Ghoroghi, Shima, Collot, Mayeul, Bons, Joanna, Follain, Gautier, Harlepp, Sébastien, Mary, Benjamin, Bauer, Jack, Mercier, Luc, Busnelli, Ignacio, Lefebvre, Olivier, Fekonja, Nina, Garcia-Leon, Maria J., Machado, Pedro, Delalande, François, López, Ana Amor, Silva, Susana Garcia, Verweij, Frederik J., van Niel, Guillaume, Djouad, Farida, Peinado, Héctor, Carapito, Christine, Klymchenko, Andrey S., Goetz, Jacky G.

“…Tumor extracellular vesicles (EVs) mediate the communication between tumor and stromal cells mostly to the benefit of tumor progression. Notably, tumor EVs…”
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Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases by Mittelheisser, Vincent, Gensbittel, Valentin, Bonati, Lucia, Li, Weilin, Tang, Li, Goetz, Jacky G.

“…Disease progression is usually accompanied by changes in the biochemical composition of cells and tissues and their biophysical properties. For instance,…”
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Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration by Hetmanski, Joseph H.R., de Belly, Henry, Busnelli, Ignacio, Waring, Thomas, Nair, Roshna V., Sokleva, Vanesa, Dobre, Oana, Cameron, Angus, Gauthier, Nils, Lamaze, Christophe, Swift, Joe, del Campo, Aránzazu, Starborg, Tobias, Zech, Tobias, Goetz, Jacky G., Paluch, Ewa K., Schwartz, Jean-Marc, Caswell, Patrick T.

“…In development, wound healing, and cancer metastasis, vertebrate cells move through 3D interstitial matrix, responding to chemical and physical guidance cues…”
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Extracellular Vesicles: Catching the Light in Zebrafish by Verweij, Frederik J., Hyenne, Vincent, Van Niel, Guillaume, Goetz, Jacky G.

“…Extracellular vesicles (EVs) circulate in the body fluids of all organisms where they participate in intercellular cross-organ communication. Tracking and…”
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Tracking Mechanisms of Viral Dissemination In Vivo by Gaudin, Raphael, Goetz, Jacky G.

“…Dissemination and replication of viruses into hosts is a multistep process where viral particles infect, navigate, and indoctrinate various cell types. Viruses…”
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Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice by Bouchaala, Redouane, Mercier, Luc, Andreiuk, Bohdan, Mély, Yves, Vandamme, Thierry, Anton, Nicolas, Goetz, Jacky G., Klymchenko, Andrey S.

“…Lipid nanocarriers are considered as promising candidates for drug delivery and cancer targeting because of their low toxicity, biodegradability and capacity…”
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Synergistic Mechano-Chemical Sensing by Vascular Cilia by Follain, Gautier, Goetz, Jacky G.

“…Endothelial cells can sense and respond to blood flow forces and signals, but the exact mechanisms employed remain poorly understood. A recent study describes…”
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The microenvironment controls invadosome plasticity by Di Martino, Julie, Henriet, Elodie, Ezzoukhry, Zakaria, Goetz, Jacky G, Moreau, Violaine, Saltel, Frederic

“…Invadosomes are actin-based structures involved in extracellular matrix degradation. Invadosomes is a term that includes podosomes and invadopodia, which…”
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Exploiting Anatomical Landmarks for Efficient In Vivo CLEM by Goetz, Jacky G.

“…Established protocols for correlating intravital microscopy with electron microscopy remain cumbersome and mostly rely on a combination of artificial fiducials…”
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Fluorescent Polymer Nanoparticles for Cell Barcoding In Vitro and In Vivo by Andreiuk, Bohdan, Reisch, Andreas, Lindecker, Marion, Follain, Gautier, Peyriéras, Nadine, Goetz, Jacky G., Klymchenko, Andrey S.

“…Fluorescent polymer nanoparticles for long‐term labeling and tracking of living cells with any desired color code are developed. They are built from…”
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Intravital Correlative Microscopy: Imaging Life at the Nanoscale by Karreman, Matthia A, Hyenne, Vincent, Schwab, Yannick, Goetz, Jacky G

“…Studying key biological events within complex model systems relies on dynamic and functional imaging at optimum spatial and temporal resolutions. Intravital…”
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Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development by Goetz, Jacky G., Steed, Emily, Ferreira, Rita R., Roth, Stéphane, Ramspacher, Caroline, Boselli, Francesco, Charvin, Gilles, Liebling, Michael, Wyart, Claire, Schwab, Yannick, Vermot, Julien

“…The pattern of blood flow has long been thought to play a significant role in vascular morphogenesis, yet the flow-sensing mechanism that is involved at early…”
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RAL-1 controls multivesicular body biogenesis and exosome secretion by Hyenne, Vincent, Apaydin, Ahmet, Rodriguez, David, Spiegelhalter, Coralie, Hoff-Yoessle, Sarah, Diem, Maxime, Tak, Saurabh, Lefebvre, Olivier, Schwab, Yannick, Goetz, Jacky G, Labouesse, Michel

“…Exosomes are secreted vesicles arising from the fusion of multivesicular bodies (MVBs) with the plasma membrane. Despite their importance in various processes,…”
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Organelle morphology and positioning orchestrate physiological and disease-associated processes by Jerabkova-Roda, Katerina, Marwaha, Rituraj, Das, Tamal, Goetz, Jacky G.

“…In cells, organelles are distributed nonrandomly to regulate cells' physiological and disease-associated processes. Based on their morphology, position within…”
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