Search Results - "Goelz, Susan"

Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy by Bloomgren, Gary, Richman, Sandra, Hotermans, Christophe, Subramanyam, Meena, Goelz, Susan, Natarajan, Amy, Lee, Sophia, Plavina, Tatiana, Scanlon, James V, Sandrock, Alfred, Bozic, Carmen

“…In patients treated with natalizumab, PML incidence was about 11 cases per 1000 patients with 25 to 48 months of treatment, prior immunosuppressant use, and…”
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A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity by Chung, Kyoung-Jin, Chatzigeorgiou, Antonios, Economopoulou, Matina, Garcia-Martin, Ruben, Alexaki, Vasileia I, Mitroulis, Ioannis, Nati, Marina, Gebler, Janine, Ziemssen, Tjalf, Goelz, Susan E, Phieler, Julia, Lim, Jong-Hyung, Karalis, Katia P, Papayannopoulou, Thalia, Blüher, Matthias, Hajishengallis, George, Chavakis, Triantafyllos

“…Obesity is commonly accompanied by inflammatory responses in white adipose tissues. Chavakis and colleagues identify a vicious cycle involving α 4 integrins…”
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Anti-JC virus antibodies: Implications for PML Risk Stratification by Gorelik, Leonid, Lerner, Michaela, Bixler, Sarah, Crossman, Mary, Schlain, Brian, Simon, Kenneth, Pace, Amy, Cheung, Anne, Chen, Ling Ling, Berman, Melissa, Zein, Fairuz, Wilson, Ewa, Yednock, Ted, Sandrock, Alfred, Goelz, Susan E., Subramanyam, Meena

“…Objective A study was undertaken to establish an enzyme‐linked immunosorbent assay (ELISA) to detect JC virus (JCV)‐specific antibodies in multiple sclerosis…”
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Assessment of JC virus DNA in blood and urine from natalizumab-treated patients by Rudick, Richard A., O'Connor, Paul W., Polman, Chris H., Goodman, Andrew D., Ray, Soma S., Griffith, Nancy M., Jurgensen, Stephanie A., Gorelik, Leonid, Forrestal, Fiona, Sandrock, Alfred W., E. Goelz, Susan

“…Objective Analyses were conducted to determine the clinical utility of measuring JC virus (JCV) DNA in blood or urine of natalizumab‐treated multiple sclerosis…”
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Beta-interferon for multiple sclerosis by Rudick, Richard A., Goelz, Susan E.

“…Interferon beta is widely used as first-line treatment for relapsing remitting multiple sclerosis (RRMS). Several products are marketed world-wide, and…”
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JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection by Wharton, Jr, Keith A, Quigley, Catherine, Themeles, Marian, Dunstan, Robert W, Doyle, Kathryn, Cahir-McFarland, Ellen, Wei, Jing, Buko, Alex, Reid, Carl E, Sun, Chao, Carmillo, Paul, Sur, Gargi, Carulli, John P, Mansfield, Keith G, Westmoreland, Susan V, Staugaitis, Susan M, Fox, Robert J, Meier, Werner, Goelz, Susan E

“…Over half of adults are seropositive for JC polyomavirus (JCV), but rare individuals develop progressive multifocal leukoencephalopathy (PML), a demyelinating…”
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L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients by Schwab, Nicholas, Schneider-Hohendorf, Tilman, Posevitz, Vilmos, Breuer, Johanna, Göbel, Kerstin, Windhagen, Susanne, Brochet, Bruno, Vermersch, Patrick, Lebrun-Frenay, Christine, Posevitz-Fejfár, Anita, Capra, Ruggero, Imberti, Luisa, Straeten, Vera, Haas, Juergen, Wildemann, Brigitte, Havla, Joachim, Kümpfel, Tania, Meinl, Ingrid, Niessen, Kyle, Goelz, Susan, Kleinschnitz, Christoph, Warnke, Clemens, Buck, Dorothea, Gold, Ralf, Kieseier, Bernd C., Meuth, Sven G., Foley, John, Chan, Andrew, Brassat, David, Wiendl, Heinz

“…OBJECTIVE:To find biomarkers identifying patients at risk for the development of progressive multifocal leukoencephalopathy (PML) during natalizumab treatment…”
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High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4 + T cell arrest on the inflamed BBB under flow in vitro by Soldati, Sasha, Bär, Alexander, Vladymyrov, Mykhailo, Glavin, Dale, McGrath, James L, Gosselet, Fabien, Nishihara, Hideaki, Goelz, Susan, Engelhardt, Britta

“…The humanized anti-α4 integrin blocking antibody natalizumab (NTZ) is an effective treatment for relapsing-remitting multiple sclerosis (RRMS) that is…”
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Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients by Reid, Carl E., Li, Huo, Sur, Gargi, Carmillo, Paul, Bushnell, Steven, Tizard, Rich, McAuliffe, Michele, Tonkin, Christopher, Simon, Kenneth, Goelz, Susan, Cinque, Paola, Gorelik, Leonid, Carulli, John P.

“…Background. Progressive multifocal leukoencephalopathy (PML) in natalizumab-treated MS patients is linked to JC virus (JCV) infection. JCV sequence variation…”
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Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles by Oberholster, Larise, Mathias, Amandine, Perriot, Sylvain, Blaser, Emma, Canales, Mathieu, Jones, Samuel, Culebras, Lucas, Gimenez, Marie, Kaynor, G Campbell, Sapozhnik, Alexey, Richetin, Kevin, Goelz, Susan, Du Pasquier, Renaud

“…Progressive multifocal leukoencephalopathy is a crimpling demyelinating disease of the central nervous system caused by JC polyomavirus (JCPyV). Much about…”
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Assay design and sample collection can affect anti-John Cunningham virus antibody detection by Goelz, Susan E., Gorelik, Leonid, Subramanyam, Meena

“…No abstract is available for this article…”
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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway by LINKER, Ralf A, LEE, De-Hyung, ELLRICHMANN, Gisa, BRÜCK, Wolfgang, DAWSON, Kate, GOELZ, Susan, WIESE, Stefan, SCANNEVIN, Robert H, LUKASHEV, Matvey, GOLD, Ralf, RYAN, Sarah, VAN DAM, Anne M, CONRAD, Rebecca, BISTA, Pradeep, WEIKE ZENG, HRONOWSKY, Xiaoping, BUKO, Alex, CHOLLATE, Sowmya

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Feasibility of the use of combinatorial chemokine arrays to study blood and CSF in multiple sclerosis by Edwards, Keith R, Goyal, Jaya, Plavina, Tatiana, Czerkowicz, Julie, Goelz, Susan, Ranger, Ann, Cadavid, Diego, Browning, Jeffrey L

“…Meningeal inflammation, including the presence of semi-organized tertiary lymphoid tissue, has been associated with cortical pathology at autopsy in secondary…”
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Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment by Blank, Thomas, Detje, Claudia N., Spieß, Alena, Hagemeyer, Nora, Brendecke, Stefanie M., Wolfart, Jakob, Staszewski, Ori, Zöller, Tanja, Papageorgiou, Ismini, Schneider, Justus, Paricio-Montesinos, Ricardo, Eisel, Ulrich L.M., Manahan-Vaughan, Denise, Jansen, Stephan, Lienenklaus, Stefan, Lu, Bao, Imai, Yumiko, Müller, Marcus, Goelz, Susan E., Baker, Darren P., Schwaninger, Markus, Kann, Oliver, Heikenwalder, Mathias, Kalinke, Ulrich, Prinz, Marco

“…Sickness behavior and cognitive dysfunction occur frequently by unknown mechanisms in virus-infected individuals with malignancies treated with type I…”
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The effect of plasma exchange on serum anti-JC virus antibodies by Subramanyam, Meena, Plavina, Tatiana, Khatri, Bhupendra O, Fox, Robert J, Goelz, Susan E

“…Objective: Natalizumab, a highly effective treatment for multiple sclerosis (MS) and Crohn’s disease, is associated with progressive multifocal…”
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Anatomic Closure of the Premature Patent Ductus Arteriosus: The Role of CD14+/CD163+ Mononuclear Cells and VEGF in Neointimal Mound Formation by Waleh, Nahid, Seidner, Steven, McCurnin, Donald, Giavedoni, Luis, Hodara, Vida, Goelz, Susan, Liu, Bao Mei, Roman, Christine, Clyman, Ronald I

“…Permanent closure of the newborn ductus arteriosus requires the development of neointimal mounds to completely occlude its lumen. VEGF is required for…”
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Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders by Haghikia, Aiden, Perrech, Moritz, Pula, Bartosz, Ruhrmann, Sabrina, Potthoff, Anja, Brockmeyer, Norbert H, Goelz, Susan, Wiendl, Heinz, Lindå, Hans, Ziemssen, Tjalf, Baranzini, Sergio E, Käll, Tor-Björn, Bengel, Dietmar, Olsson, Tomas, Gold, Ralf, Chan, Andrew

“…Progressive multifocal leukoencephalopathy (PML) is an opportunistic central nervous system- (CNS-) infection that typically occurs in a subset of…”
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Evaluation of the Incidence of Anti-JC Virus Antibodies in a Cohort of Natalizumab-Treated Patients by Pepio, Anthony M, Taylor, Lori, Jaros, Mark, Mocci, Simonetta, Yednock, Ted, Hogge, Gary S, Plavina, Tatiana, Gorelik, Leonid, Goelz, Susan E, Natarajan, Amy, Lee, Sophia, Richman, Sandra, Subramanyam, Meena

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Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1 by David, Michael, Chen, Haiyan E., Goelz, Susan, Larner, Andrew C., Neel, Benjamin G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The crystal structure of human interferon β at 2.2-Å resolution by Karpusas, M, Nolte, M, Benton, C B, Meier, W, Lipscomb, W N, Goelz, S

“…Type I interferons (IFNs) are helical cytokines that have diverse biological activities despite the fact that they appear to interact with the same receptor…”
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