Search Results - "Goekoop, R"

Hierarchical network structure as the source of hierarchical dynamics (power-law frequency spectra) in living and non-living systems: How state-trait continua (body plans, personalities) emerge from first principles in biophysics by Goekoop, R., de Kleijn, R.

“…Living systems are hierarchical control systems that display a small world network structure. In such structures, many smaller clusters are nested within fewer…”
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Amnestic Mild Cognitive Impairment: Structural MR Imaging Findings Predictive of Conversion to Alzheimer Disease by Karas, G, Sluimer, J, Goekoop, R, van der Flier, W, Rombouts, S.A.R.B, Vrenken, H, Scheltens, P, Fox, N, Barkhof, F

“…Mild cognitive impairment (MCI) is considered by many to be a prodromal phase of Alzheimer disease (AD). We used voxel-based morphometry (VBM) to find out…”
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A two-step treatment strategy trial in patients with early arthritis aimed at achieving remission: the IMPROVED study by Heimans, L, Wevers-de Boer, K V C, Visser, K, Goekoop, R J, van Oosterhout, M, Harbers, J B, Bijkerk, C, Speyer, I, de Buck, M P D M, de Sonnaville, P B J, Grillet, B A M, Huizinga, T W J, Allaart, C F

“…To assess which treatment strategy is most effective in inducing remission in early (rheumatoid) arthritis. 610 patients with early rheumatoid arthritis (RA…”
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EPA-1590 - The network structure of psychopathology according to the cprs: network communities as elementary syndromes of psychopathology by Goekoop, R, Goekoop, J.G

“…Introduction The vast number of psychopathological syndromes that can be observed in clinical practice can be described in terms of a limited set of elementary…”
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Determinants of absence of osteoarthritis in old age by Goekoop, RJ, Kloppenburg, M, Kroon, HM, Dirkse, LEV, Huizinga, TWJ, Westendorp, RGJ, Gussekloo, J

“…Objective: To investigate factors associated with absence of osteoarthritis (OA). Methods: In 82 well-functioning 90-year-old participants from a…”
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Four-month metacarpal bone mineral density loss predicts radiological joint damage progression after 1 year in patients with early rheumatoid arthritis: exploratory analyses from the IMPROVED study by Wevers-de Boer, K V C, Heimans, L, Visser, K, Kälvesten, J, Goekoop, R J, van Oosterhout, M, Harbers, J B, Bijkerk, C, Steup-Beekman, M, de Buck, M P D M, de Sonnaville, P B J, Huizinga, T W J, Allaart, C F

“…To assess whether in early (rheumatoid) arthritis (RA) patients, metacarpal bone mineral density (BMD) loss after 4 months predicts radiological progression…”
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Safety of excluding acute pulmonary embolism based on an unlikely clinical probability by the Wells rule and normal D-dimer concentration: A meta-analysis by Pasha, S.M, Klok, F.A, Snoep, J.D, Mos, I.C.M, Goekoop, R.J, Rodger, M.A, Huisman, M.V

“…Abstract Introduction The Wells clinical decision rule (CDR) and D-dimer tests can be used to exclude pulmonary embolism (PE). We performed a meta-analysis to…”
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Not All Age-Related White Matter Hyperintensities Are the Same: A Magnetization Transfer Imaging Study by Spilt, A, Goekoop, R, Westendorp, R.G.J, Blauw, G.J, de Craen, A.J.M, van Buchem, M.A

“…Our aim was to assess whether presumed histologic heterogeneity of age-related white matter hyperintensities (WMH) is reflected in quantitative magnetization…”
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C‐reactive protein and D‐dimer with clinical probability score in the exclusion of pulmonary embolism by Steeghs, N., Goekoop, R. J., Niessen, R. W. L. M., Jonkers, G. J. P. M., Dik, H., Huisman, M. V.

“…Summary This study evaluated the diagnostic value of C‐reactive protein (CRP) combined with a clinical decision rule in the exclusion of pulmonary embolism…”
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Loss of frontal fMRI activation in early frontotemporal dementia compared to early AD by ROMBOUTS, S. A. R. B, VAN SWIETEN, J. C, PIJNENBURG, Y. A. L, GOEKOOP, R, BARKHOF, F, SCHELTENS, P

“…To compare frontal cortex activation in patients with early frontotemporal dementia (FTD) with that in patients with early AD. Seven patients with FTD and…”
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Raloxifene exposure enhances brain activation during memory performance in healthy elderly males; its possible relevance to behavior by Goekoop, R., Duschek, E.J.J., Knol, D.L., Barkhof, F., Netelenbos, C., Scheltens, Ph, Rombouts, S.A.R.B.

“…Raloxifene is a selective estrogen receptor modulator (SERM) that is prescribed in females only, but its use in male subjects is increasingly considered. With…”
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Interindividual differences of medial temporal lobe activation during encoding in an elderly population studied by fMRI by Vandenbroucke, M.W.G, Goekoop, R, Duschek, E.J.J, Netelenbos, J.C, Kuijer, J.P.A, Barkhof, F, Scheltens, Ph, Rombouts, S.A.R.B

“…Functional MRI (fMRI) is used to study medial temporal lobe (MTL) activation during encoding of new information into memory. In most studies, fMRI data of…”
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Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study by Rombouts, Serge A.R.B., Barkhof, Frederik, Goekoop, Rutger, Stam, Cornelis J., Scheltens, Philip

“…Activity and reactivity of the default mode network in the brain was studied using functional magnetic resonance imaging (fMRI) in 28 nondemented individuals…”
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Network clusters of symptoms as elementary syndromes of psychopathology: implications for clinical practice by Goekoop, R, Goekoop, J G

“…In a recent publication we reported the existence of around 11 (to 15) 'elementary syndromes' that may combine in various ways, rather like 'building blocks',…”
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Noradrenaline mediates amygdala activation in men and women during encoding of emotional material by van Stegeren, Anda H., Goekoop, Rutger, Everaerd, Walter, Scheltens, Philip, Barkhof, Frederik, Kuijer, Joost P.A., Rombouts, Serge A.R.B.

“…The amygdala is a pivotal structure in humans for encoding of emotional information, as shown by recent imaging studies. It is unknown which neurotransmitters…”
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Low innate production of interleukin-1β and interleukin-6 is associated with the absence of osteoarthritis in old age by Goekoop, R.J, Kloppenburg, M, Kroon, H.M, Frölich, M, Huizinga, T.W.J, Westendorp, R.G.J, Gussekloo, J

“…Summary Objective We investigated whether innate differences in cytokine response were associated with the absence of osteoarthritis (OA) in old age. Design In…”
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Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease by Rombouts, Serge A.R.B., Goekoop, Rutger, Stam, Cornelis J., Barkhof, Frederik, Scheltens, Philip

“…Functional MRI (fMRI) in established Alzheimer's disease (AD) shows regionally altered blood oxygenation level dependent (BOLD) responses. Mild cognitive…”
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Opening the black box of non-pharmacological care in systemic sclerosis: a cross-sectional online survey of Dutch health professionals by Stöcker, Juliane K., Vonk, Madelon C., van den Hoogen, Frank H. J., Nijhuis-van der Sanden, Maria W. G., Spierings, Julia, Staal, J. Bart, Satink, Ton, van den Ende, Cornelia H. M.

“…The objective is to describe the spectrum of the health professional (HP) treatment approach for systemic sclerosis (SSc) from the perspective of Dutch HPs,…”
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Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation—a pharmacological fMRI study by Goekoop, Rutger, Scheltens, Philip, Barkhof, Frederik, Rombouts, Serge A. R. B.

“…Pharmacological functional MRI (phMRI) examines the impact of pharmacologically induced neurochemical changes on brain function at a system level. The current…”
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Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study by Goekoop, Rutger, Rombouts, Serge A.R.B., Jonker, Cees, Hibbel, Anneke, Knol, Dirk L., Truyen, Luc, Barkhof, Frederik, Scheltens, Philip

“…Mild cognitive impairment (MCI) often represents an early form of Alzheimer disease (AD). In both MCI and AD, characteristic cholinergic changes may occur…”
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