Search Results - "Goekler, Johannes"
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An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms
Published in The Journal of heart and lung transplantation (01-06-2019)“…We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype…”
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Exploring the cardiac response to injury in heart transplant biopsies
Published in JCI insight (18-10-2018)“…Because injury is universal in organ transplantation, heart transplant endomyocardial biopsies present an opportunity to explore response to injury in heart…”
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Cardiac Surgery After Heart Transplantation: Elective Operation or Last Exit Strategy?
Published in Transplantation direct (01-10-2017)“…Because of improved long-term survival after heart transplantation (HTx), late graft pathologies such as valvular disease or cardiac allograft vasculopathy…”
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Absolute Lymphocyte Count as a Marker for Cytomegalovirus Infection After Heart Transplantation
Published in Transplantation (01-03-2023)“…Previous studies indicate an association between reduced absolute lymphocyte count (ALC) and cytomegalovirus (CMV) infection after solid organ transplantation…”
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Absolute Lymphocyte Count as a Marker for Cytomegalovirus Infection After Heart Transplantation
Published in Transplantation (13-10-2022)Get full text
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Transcatheter tricuspid valve edge-to-edge repair after a heart transplant: a single-centre experience with a novel therapy
Published in European journal of cardio-thoracic surgery (01-06-2023)“…Abstract OBJECTIVES Tricuspid regurgitation (TR) in patients who had heart transplants is associated with poor outcome. The increased risk for surgical and…”
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Extracorporeal Photopheresis With Low-Dose Immunosuppression in High-Risk Heart Transplant Patients-A Pilot Study
Published in Transplant international (23-03-2022)“…In severely ill patients undergoing urgent heart transplant (HTX), immunosuppression carries high risks of infection, malignancy, and death. Low-dose…”
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Redefining the molecular rejection states in 3230 heart transplant biopsies: Relationships to parenchymal injury and graft survival
Published in American journal of transplantation (01-08-2024)“…The first-generation Molecular Microscope (MMDx) system for heart transplant endomyocardial biopsies used expression of rejection-associated transcripts (RATs)…”
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Assessing the Relationship Between Molecular Rejection and Parenchymal Injury in Heart Transplant Biopsies
Published in Transplantation (15-08-2022)Get full text
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Assessing the Relationship Between Molecular Rejection and Parenchymal Injury in Heart Transplant Biopsies
Published in Transplantation (01-11-2022)“…Background. The INTERHEART study (ClinicalTrials.gov #NCT02670408) used genome-wide microarrays to detect rejection in endomyocardial biopsies; however, many…”
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High-dose catecholamine donor support and outcomes after heart transplantation
Published in The Journal of heart and lung transplantation (01-05-2018)“…Higher dose norepinephrine donor support is a frequent reason for donor heart decline, but its associations with outcomes after heart transplantation are…”
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Extracorporeal Photopheresis (ECP) and Calcineurin Inhibitor (CNI) delay after Heart Transplantation
Published in Transplantation (01-07-2018)“…INTRODUCTIONECP is an established therapy for prevention of acute rejection perioperatively and for treatment of recurrent, therapy resistant rejections after…”
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Molecular Assessment of Heart Transplant Biopsies: Emergence of the Injury Dimension
Published in Transplantation (01-07-2018)“…INTRODUCTIONWe previously developed a molecular diagnostic system for assessment of rejection phenotypes in endomyocardial biopsies (EMB) based on expression…”
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Impact of Rabbit Antithymocyte Globulin Dose on Long-term Outcomes in Heart Transplant Patients
Published in Transplantation (01-03-2016)“…Optimal dosing strategies have not been established for rabbit antithymocyte globulin (rATG) after heart transplantation, and there is currently wide…”
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Donor heart selection and outcomes: An analysis of over 2,000 cases
Published in The Journal of heart and lung transplantation (01-08-2018)“…Decision-making when offered a donor heart for transplantation is complex, and supportive data describing outcomes according to acceptance or non-acceptance…”
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Prioritizing direct heart procurement in organ donors after circulatory death does not jeopardize lung transplant outcomes
Published in JTCVS techniques (01-12-2022)“…Controlled donation after circulatory death (cDCD) has become a standard in liver, kidney, and lung transplantation (LTx). Based on recent innovations in…”
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Reduction ascending aortoplasty: A retrospective analysis of outcomes and risk factors
Published in Frontiers in cardiovascular medicine (25-07-2022)“…Objectives Indication for Reduction of Ascending Aortoplasty (RAA) and long-term outcomes remain unclear. This study analyzed the outcomes after nonreinforced…”
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Diminished impact of cytomegalovirus infection on graft vasculopathy development in the antiviral prophylaxis era - a retrospective study
Published in Transplant international (01-08-2018)“…Evidence concerning an association between cytomegalovirus (CMV) infection and accelerated cardiac allograft vasculopathy (CAV) is inconclusive. Data were…”
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Lack of donor and recipient age interaction in cardiac transplantation
Published in The Journal of heart and lung transplantation (01-06-2014)“…Background The proportion of older donors and recipients is constantly rising in heart transplantation (HTX). The impact of age on different outcomes after HTX…”
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Indications, Complications, and Outcomes of Cardiac Surgery After Heart Transplantation: Results From the Cash Study
Published in Frontiers in cardiovascular medicine (09-06-2022)“…Allograft pathologies, such as valvular, coronary artery, or aortic disease, may occur early and late after cardiac transplantation. Cardiac surgery after…”
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