Search Results - "Goehler, T"

Phase-field modeling of the γ′-coarsening behavior in Ni-based superalloys by Kundin, J., Mushongera, L., Goehler, T., Emmerich, H.

“…Microstructural changes during heat treatment of the Ni-based CMSX-4 and CMSX-6 superalloys have been investigated experimentally and simulated using a…”
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576PImpact of prophylactic systemic antibiotics (SA) on outcome of patients (pts) with RAS-wildtype (RAS-wt) metastatic colorectal carcinoma (mCRC) treated with cetuximab-based first-line therapy. Subgroup analysis of the german non-interventional study ERBITAG by Sahm, S W, Zahn, M-O, Maintz, C, Goehler, T, Janssen, J, Hering-Schubert, C, Rubanov, O, Zander, I, Stenzel, K G, Overkamp, F

“…Abstract Background SA are widely used and recommended to ameliorate skin reactions induced by EGFR inhibition. Randomised studies have shown a positive impact…”
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576P - Impact of prophylactic systemic antibiotics (SA) on outcome of patients (pts) with RAS-wildtype (RAS-wt) metastatic colorectal carcinoma (mCRC) treated with cetuximab-based first-line therapy. Subgroup analysis of the german non-interventional study ERBITAG by Sahm, S.W., Zahn, M.-O., Maintz, C., Goehler, T., Janssen, J., Hering-Schubert, C., Rubanov, O., Zander, I., Stenzel, K.G., Overkamp, F.

“…SA are widely used and recommended to ameliorate skin reactions induced by EGFR inhibition. Randomised studies have shown a positive impact of SA on severity…”
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Impact of prophylactic systemic antibiotics (SA) on outcome of patients (pts) with RAS-wildtype (RAS-wt) metastatic colorectal carcinoma (mCRC) treated with cetuximab-based first-line therapy. Subgroup analysis of the german non-interventional study ERBITAG by Sahm, S.W., Zahn, M.-O., Maintz, C., Goehler, T., Janssen, J., Hering-Schubert, C., Rubanov, O., Zander, I., Stenzel, K.G., Overkamp, F.

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Systematic Phase-Field Study on Microstructure Formation During Brazing of Mar-M247 with a Si-Based AMS4782 Filler by Böttger, B., Apel, M., Daniels, B., Dankl, L., Göhler, T., Jokisch, T.

“…Although advanced solidification processes like high temperature brazing have gained more and more industrial importance, they still are often not well…”
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Impact of surgical resection of liver metastases on outcome of patients with KRAS-wildtype exon 2 (KRAS-wt) metastatic colorectal carcinoma (mCRC) treated with a cetuximab-based first-line therapy - Interim analysis of the German non-interventional study ERBITAG by Neumann, U., Goehler, T., Hering-Schubert, C., Janssen, J., Sahm, S., Schwittay, M., Zahn, M.O., Stenzel, K.G., Overkamp, F.

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Final Analysis of Overall Survival Per Subgroups of Hcc Patients in the Prospective, Non-Interventional Insight Study Treated with Sorafenib by Ganten, T.M., Stauber, R., Schott, E., Malfertheiner, P., Buder, R., Galle, P.R., Goehler, T., Bernard, I., Gerken, G.

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728PFINAL ANALYSIS OF OVERALL SURVIVAL PER SUBGROUPS OF HCC PATIENTS IN THE PROSPECTIVE, NON-INTERVENTIONAL INSIGHT STUDY TREATED WITH SORAFENIB by Ganten, T.M., Stauber, R., Schott, E., Malfertheiner, P., Buder, R., Galle, P.R., Goehler, T., Bernard, I., Gerken, G.

“…Abstract Aim: INSIGHT is a prospective, non-interventional study, conducted in Germany and Austria in pts with hepatocellular carcinoma HCC. The objectives of…”
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Abstract P1-15-02: Febrile neutropenia (FN) risk assessment and granulocyte colony-stimulating factor (G-CSF) guideline adherence in patients with breast cancer – results from a German prospective multicentre observational study (PROTECT) by Steffens, C-C, Eschenburg, H, Kurbacher, C, Goehler, T, Schmidt, M, Eustermann, H, Schaffrik, M, Otremba, B

“…Background: FN is a dose-limiting toxicity of chemotherapy which can affect patient (pt) outcomes. EORTC guidelines recommend G-CSF primary prophylaxis when…”
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Impact of trastuzumab treatment beyond disease progression for advanced/metastatic breast cancer on survival – Results from a prospective, observational study in Germany by Jackisch, C, Welslau, M, Schoenegg, W, Selbach, J, Harich, H.-D, Schröder, J, Schmidt, M, Göhler, T, Eustermann, H, Ringel, R, Hinke, A

“…Abstract Objectives Evidence suggests that continued trastuzumab therapy beyond progression (TBP) may provide additional survival benefit. Within the framework…”
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Near-field optical characterization of surface-plasmon-mediated light emission from electrically biased metal-insulator-semiconductor tunnel junctions by Seidel, J., Göhler, T., Grafström, S., Eng, L. M.

“…We report on near-field optical observations of surface-plasmon-mediated light emission in electrically biased metal-insulator-semiconductor (MIS) tunnel…”
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24-month follow-up from the Patient’s Anastrozole Compliance to Therapy (PACT) program evaluating the influence of a standardized information service on compliance in postmenopausal women with early breast cancer by Lück, H., Hadji, P., Harbeck, N., Jackisch, C., Blettner, M., Glados, M., Terhaag, J., Hackenberg, R., Goehler, T., Zaun, S., Rexrodt von Fircks, A., Kreienberg, R.

“…Abstract only…”
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A multicentric observational trial with metastatic breast cancer (MBC) patients on pegylated liposomal doxorubicin (PLD) regimen by Huober, J. B., Fett, W., Nusch, A., Neise, M., Schmidt, M., Wischnik, A., Gerhard, S., Goehler, T., Rost, A.

“…Abstract only…”
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Analysis of p53 "latency" and "activation" by fluorescence correlation spectroscopy. Evidence for different modes of high affinity DNA binding by Wölcke, Julian, Reimann, Maurice, Klumpp, Martin, Göhler, Thomas, Kim, Ella, Deppert, Wolfgang

“…The concept that the tumor suppressor p53 is a latent DNA-binding protein that must become activated for sequence-specific DNA binding recently has been…”
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Specific Interaction of p53 with Target Binding Sites Is Determined by DNA Conformation and Is Regulated by the C-terminal Domain by Göhler, Thomas, Reimann, Maurice, Cherny, Dimitry, Walter, Korden, Warnecke, Gabriele, Kim, Ella, Deppert, Wolfgang

“…Transcriptional activation of p53-regulated genes is initiated by sequence-specific DNA binding of p53 to target binding sites. Regulation of sequence-specific…”
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