Search Results - "Goedhals, Dominique"

Comorbidities in SARS-CoV-2 Patients: a Systematic Review and Meta-Analysis by Ng, Wern Hann, Tipih, Thomas, Makoah, Nigel A, Vermeulen, Jan-G, Goedhals, Dominique, Sempa, Joseph B, Burt, Felicity J, Taylor, Adam, Mahalingam, Suresh

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the globe at unprecedented speed and is showing no signs of slowing…”
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Sixteen novel lineages of SARS-CoV-2 in South Africa by Tegally, Houriiyah, Wilkinson, Eduan, Lessells, Richard J., Giandhari, Jennifer, Pillay, Sureshnee, Msomi, Nokukhanya, Mlisana, Koleka, Bhiman, Jinal N., von Gottberg, Anne, Walaza, Sibongile, Fonseca, Vagner, Allam, Mushal, Ismail, Arshad, Glass, Allison J., Engelbrecht, Susan, Van Zyl, Gert, Preiser, Wolfgang, Williamson, Carolyn, Petruccione, Francesco, Sigal, Alex, Gazy, Inbal, Hardie, Diana, Hsiao, Nei-yuan, Martin, Darren, York, Denis, Goedhals, Dominique, San, Emmanuel James, Giovanetti, Marta, Lourenço, José, Alcantara, Luiz Carlos Junior, de Oliveira, Tulio

“…The first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in South Africa was identified on 5 March 2020, and by 26 March the country…”
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Sindbis Virus Antibody Seroprevalence in Central Plateau Populations, South Africa by Kennedy, Nicole, Goedhals, Dominique, Vawda, Sabeehah, Bester, Philip Armand, Burt, Felicity

“…We report a higher percentage of Sindbis virus-specific IgG in serum from patients attending a rheumatology clinic (18.8%) compared with healthy residents…”
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Long-lived CD8+ T cell responses following Crimean-Congo haemorrhagic fever virus infection by Goedhals, Dominique, Paweska, Janusz T, Burt, Felicity J

“…Crimean-Congo haemorrhagic fever virus (CCHFV) is a member of the Orthonairovirus genus of the Nairoviridae family and is associated with haemorrhagic fever in…”
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Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa by Sondlane, Hlengiwe, Ogunbayo, Ayodeji, Donato, Celeste, Mogotsi, Milton, Esona, Mathew, Hallbauer, Ute, Bester, Phillip, Goedhals, Dominique, Nyaga, Martin

“…•The COVID-19 pandemic caused significant disruptions to the prevalence and spread of respiratory syncytial virus (RSV) and other respiratory viral infections…”
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Corrigendum to “Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa” [Virus Research, Volume 347, September 2024, 199421] by Sondlane, Hlengiwe, Ogunbayo, Ayodeji, Donato, Celeste, Mogotsi, Milton, Esona, Mathew, Hallbauer, Ute, Bester, Phillip, Goedhals, Dominique, Nyaga, Martin

“…Respiratory syncytial virus (RSV) is the most predominant viral pathogen worldwide in children with lower respiratory tract infections. The coronavirus disease…”
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Seroepidemiologic Survey of Crimean-Congo Hemorrhagic Fever Virus in Selected Risk Groups, South Africa by Vawda, Sabeehah, Goedhals, Dominique, Bester, Phillip Armand, Burt, Felicity

“…Crimean Congo hemorrhagic fever virus (CCHFV) is endemic in South Africa, but whether mild undiagnosed cases occur is unclear. In a seroepidemiologic survey,…”
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A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action by Mokaya, Jolynne, McNaughton, Anna L, Hadley, Martin J, Beloukas, Apostolos, Geretti, Anna-Maria, Goedhals, Dominique, Matthews, Philippa C

“…International sustainable development goals for the elimination of viral hepatitis as a public health problem by 2030 highlight the pressing need to optimize…”
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Hepatitis B virus seroepidemiology data for Africa: Modelling intervention strategies based on a systematic review and meta-analysis by McNaughton, Anna L, Lourenço, José, Bester, Phillip Armand, Mokaya, Jolynne, Lumley, Sheila F, Obolski, Uri, Forde, Donall, Maponga, Tongai G, Katumba, Kenneth R, Goedhals, Dominique, Gupta, Sunetra, Seeley, Janet, Newton, Robert, Ocama, Ponsiano, Matthews, Philippa C

“…International Sustainable Development Goals (SDGs) for elimination of hepatitis B virus (HBV) infection set ambitious targets for 2030. In African populations,…”
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Human MAIT cells respond to and suppress HIV-1 by Phetsouphanh, Chansavath, Phalora, Prabhjeet, Hackstein, Carl-Philipp, Thornhill, John, Munier, C Mee Ling, Meyerowitz, Jodi, Murray, Lyle, VanVuuren, Cloete, Goedhals, Dominique, Drexhage, Linnea, Moore, Rebecca, Sattentau, Quentin J, Mak, Jeffrey Yw, Fairlie, David P, Fidler, Sarah, Kelleher, Anthony D, Frater, John, Klenerman, Paul

“…Human MAIT cells sit at the interface between innate and adaptive immunity, are polyfunctional and are capable of killing pathogen infected cells via…”
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A decontamination strategy for resolving SARS-CoV-2 amplicon contamination in a next-generation sequencing laboratory by Mwangi, Peter, Mogotsi, Milton, Ogunbayo, Ayodeji, Mooko, Teboho, Maringa, Wairimu, Sondlane, Hlengiwe, Nkwadipo, Kelebogile, Adelabu, Olusesan, Bester, Philip Armand, Goedhals, Dominique, Nyaga, Martin

“…Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) amplicon contamination was discovered due to next-generation sequencing (NGS) reads mapping…”
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Moderate Levels of Pre-Treatment HIV-1 Antiretroviral Drug Resistance Detected in the First South African National Survey by Steegen, Kim, Carmona, Sergio, Bronze, Michelle, Papathanasopoulos, Maria A, van Zyl, Gert, Goedhals, Dominique, MacLeod, William, Sanne, Ian, Stevens, Wendy S

“…In order to assess the level of transmitted and/or pre-treatment antiretroviral drug resistance to HIV-1, the World Health Organization (WHO) recommends that…”
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Persistence of Crimean-Congo Hemorrhagic Fever Virus RNA by Mathengtheng, Leholonolo, Goedhals, Dominique, Bester, Phillip A, Goedhals, Jacqueline, Burt, Felicity J

“…Crimean-Congo hemorrhagic fever virus (CCHFV) causes severe disease with fatalities. Awareness of potential sources of infection is important to reduce risk to…”
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Steady-state pharmacokinetics of lamivudine in end-stage kidney failure persons with detectable and undetectable HIV-1 RNA in peritoneal dialysis effluent by Mooko, Teboho, Bisiwe, Feziwe Busiswa, Mondleki, Enkosi, Morobadi, Molefi Daniel, Chikobvu, Perpetual, Nyaga, Martin Munene, Bala, Asis, Goedhals, Dominique, Mofokeng, Thabiso Rafaki Petrus, Kemp, Gabre, Ndlovu, Kwazi Celani Zwakele

“…Renally adjusted lamivudine dosages are effective. However, some of the kidney failure patients managed with lamivudine-containing regimens are failing to…”
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Modelling cost-effectiveness of tenofovir for prevention of mother to child transmission of hepatitis B virus (HBV) infection in South Africa by Mokaya, Jolynne, Burn, Edward A O, Tamandjou, Cynthia Raissa, Goedhals, Dominique, Barnes, Eleanor J, Andersson, Monique, Pinedo-Villanueva, Rafael, Matthews, Philippa C

“…International sustainable development goals for the elimination of viral hepatitis as a public health problem by 2030 highlight the need to optimize strategies…”
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High seroprevalence of hepatitis E virus in the Free State province of South Africa by Maphumulo, Sindiswa S, Goedhals, Dominique, van Rooyen, Cornel, Vawda, Sabeehah

“…The seroepidemiology of hepatitis E virus (HEV) in South Africa is limited. We investigated anti-HEV IgM and IgG, in residual hepatitis A, B, and C negative…”
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Maintenance of Functional CD57+ Cytolytic CD4+ T Cells in HIV+ Elite Controllers by Phetsouphanh, Chansavath, Aldridge, Daniel, Marchi, Emanuele, Munier, C Mee Ling, Meyerowitz, Jodi, Murray, Lyle, Van Vuuren, Cloete, Goedhals, Dominique, Fidler, Sarah, Kelleher, Anthony, Klenerman, Paul, Frater, John

“…Cytolytic CD4+ T cells play a prominent role in chronic viral infection. CD4+ CTLs clones specific for HIV-1 Nef and Gag are capable of killing HIV-1 infected…”
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PhyloPi: An affordable, purpose built phylogenetic pipeline for the HIV drug resistance testing facility by Bester, Phillip Armand, De Vries, Andrie, Riekert, Stephanus, Steegen, Kim, van Zyl, Gert, Goedhals, Dominique

“…Phylogenetic analysis plays a crucial role in quality control in the HIV drug resistance testing laboratory. If previous patient sequence data is available…”
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Mapping the drivers of within-host pathogen evolution using massive data sets by Palmer, Duncan S., Turner, Isaac, Fidler, Sarah, Frater, John, Goedhals, Dominique, Goulder, Philip, Huang, Kuan-Hsiang Gary, Oxenius, Annette, Phillips, Rodney, Shapiro, Roger, Vuuren, Cloete van, McLean, Angela R., McVean, Gil

“…Differences among hosts, resulting from genetic variation in the immune system or heterogeneity in drug treatment, can impact within-host pathogen evolution…”
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Contamination with HIV antibody may be responsible for false positive results in specimens tested on automated platforms running HIV 4th generation assays in a region of high HIV prevalence by Hardie, Diana Ruth, Korsman, Stephen N, Hsiao, Nei-Yuan, Morobadi, Molefi Daniel, Vawda, Sabeehah, Goedhals, Dominique

“…In South Africa where the prevalence of HIV infection is very high, 4th generation HIV antibody/p24 antigen combo immunoassays are the tests of choice for…”
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