Search Results - "Goedegebuure, S A"

Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation by Goedegebuure, Ruben S A, Kleibeuker, Esther A, Buffa, Francesca M, Castricum, Kitty C M, Haider, Syed, Schulkens, Iris A, Ten Kroode, Luuk, van den Berg, Jaap, Jacobs, Maarten A J M, van Berkel, Anne-Marie, van Grieken, Nicole C T, Derks, Sarah, Slotman, Ben J, Verheul, Henk M W, Harris, Adrian L, Thijssen, Victor L

“…Improvement of radiotherapy efficacy requires better insight in the dynamic responses that occur during irradiation. Here, we aimed to identify the molecular…”
Get full text

Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer? by Goedegebuure, Ruben S A, de Klerk, Leonie K, Bass, Adam J, Derks, Sarah, Thijssen, Victor L J L

“…Radiotherapy has been used for the treatment of cancer for over a century. Throughout this period, the therapeutic benefit of radiotherapy has continuously…”
Get full text

Phenotypic immune characterization of gastric and esophageal adenocarcinomas reveals profound immune suppression in esophageal tumor locations by Groen-van Schooten, Tessa S, Harrasser, Micaela, Seidel, Jens, Bos, Emma N, Fleitas, Tania, van Mourik, Monique, Pouw, Roos E, Goedegebuure, Ruben S A, Doeve, Benthe H, Sanders, Jasper, Bos, Joris, van Berge Henegouwen, Mark I, Thijssen, Victor L J L, van Grieken, Nicole C T, van Laarhoven, Hanneke W M, de Gruijl, Tanja D, Derks, Sarah

“…Tumors in the distal esophagus (EAC), gastro-esophageal junction including cardia (GEJAC), and stomach (GAC) develop in close proximity and show strong…”
Get full text

Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies by Klerk, Leonie K., Goedegebuure, Ruben S. A., Grieken, Nicole C. T., Sandick, Johanna W., Cats, Annemieke, Stiekema, Jurrien, Kaaij, Rosa T., Farina Sarasqueta, Arantza, Engeland, Manon, Jacobs, Maarten A. J. M., Wanrooij, Roy L. J., Peet, Donald L., Thorner, Aaron R., Verheul, Henk M. W., Thijssen, Victor L. J. L., Bass, Adam J., Derks, Sarah

“…Identification of molecular predictive markers of response to neoadjuvant chemoradiation could aid clinical decision‐making in patients with localized…”
Get full text

Combining Radiation Therapy With Interferons: Back to the Future by Goedegebuure, Ruben S.A., Vonk, Christian, Kooij, Laura P., Derks, Sarah, Thijssen, Victor L.J.L.

“…Radiation therapy has been linked to the induction of an intratumoral type I interferon (IFN) response, which positively affects the response to treatment…”
Get full text

Development of transient radioresistance during fractionated irradiation in vitro by van den Berg, Jaap, Castricum, Kitty C.M., Meel, Michaël H., Goedegebuure, Ruben S.A., Lagerwaard, Frank J., Slotman, Ben J., Hulleman, Esther, Thijssen, Victor L.J.L.

“…•Multiple colon and brain cancer cell lines were subjected to fractionated irradiation in vitro.•Fractionated irradiation induces transient radioresistance…”
Get full text

A Phase I Open‐Label Clinical Trial Evaluating the Therapeutic Vaccine hVEGF26–104/RFASE in Patients with Advanced Solid Malignancies by Goedegebuure, Ruben S.A., Wentink, Madelon Q., Vliet, Hans J., Timmerman, Peter, Griffioen, Arjan W., Gruijl, Tanja D., Verheul, Henk M.W.

“…Lessons Learned The novel therapeutic vaccine hVEGF26–104/RFASE was found to be safe and well tolerated in patients with cancer. hVEGF26–104/RFASE failed to…”
Get full text

P53 gene mutations in osteosarcomas in the dog by van Leeuwen, I.S., Cornelisse, C.J., Misdorp, W., Goedegebuure, S.A., Kirpensteijn, J., Rutteman, G.R.

“…Osteosarcomas in 18 dogs were examined for the presence of p53 mutations in exons 4–8 by single strand conformation polymorphism (SSCP) analysis, followed by…”
Get full text

Pre-treatment tumor-infiltrating T cells influence response to neoadjuvant chemoradiotherapy in esophageal adenocarcinoma by Goedegebuure, R.S.A., Harrasser, M., de Klerk, L.K., van Schooten, T.S., van Grieken, N.C.T., Eken, M., Grifhorst, M.S., Pocorni, N., Jordanova, E.S., van Berge Henegouwen, M.I., Pouw, R.E., Verheul, H.M.W., van der Vliet, J.J., van Laarhoven, H.W.M., Thijssen, V.L.J.L, Bass, A.J., De Gruijl, T.D., Derks, S.

“…Esophageal adenocarcinoma (EAC) is a disease with dismal treatment outcomes. Response to neoadjuvant chemoradiation (CRT) varies greatly. Although the…”
Get full text

Growth and skeletal development in Great Dane pups fed different levels of protein intake by Nap, R C, Hazewinkel, H A, Voorhout, G, Van den Brom, W E, Goedegebuure, S A, Van 'T Klooster, A T

“…Feeding a dog of a large breed with a diet exceeding the National Research Council (1974) recommendations for energy, protein, calcium, phosphorus and vitamin…”
Get more information

A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene by Schatzberg, S, Olby, N, Steingold, S, Keene, B, Atkins, C, Meurs, K, Solomon, G, Goedegebuure, S A, Wilton, S, Sharp, N

“…To develop a polymerase chain reaction (PCR) strategy to screen the dystrophin promoter(s) in dogs with cardiac and skeletal myopathies. 9 Doberman Pinschers,…”
Get more information

Hysteroscopic Sterilization Using a Virtual Reality Simulator: Assessment of Learning Curve by Janse, Juliënne A., MD, Goedegebuure, Ruben S.A., MD, Veersema, Sebastiaan, MD, Broekmans, Frank J.M., MD, PhD, Schreuder, Henk W.R., MD, PhD

“…Abstract Study Objective To assess the learning curve using a virtual reality simulator for hysteroscopic sterilization with the Essure method. Design…”
Get full text

Congenital lobar emphysema caused by aplasia of bronchial cartilage in a Pekingese puppy by Voorhout, G, Goedegebuure, S A, Nap, R C

Get more information

Electromyography of the pelvic diaphragm and anal sphincter in dogs with perineal hernia by Sjollema, B E, Venker-van Haagen, A J, van Sluijs, F J, Hartman, F, Goedegebuure, S A

“…The innervation of the levator ani and coccygeal muscles and the external anal sphincter was studied by anatomic dissection in 6 clinically normal male dogs…”
Get more information

The site of focal osteomyelitis lesions in foals by Firth, E C, Goedegebuure, S A

“…The long bone ends of foals with infectious disease were sawn into sagittal slabs, washed and inspected. Tissue suspected to be abnormal on the basis of change…”
Get more information

The arterial supply of the navicular bone in adult horses with navicular disease by Rijkenhuizen, A B, Németh, F, Dik, K J, Goedegebuure, S A

“…A macroscopical, arteriographical and histological study was made of the arterial supply of the navicular bones of horses with clinical and/or radiographic…”
Get more information

Morphological findings in young dogs chronically fed a diet containing excess calcium by Goedegebuure, S A, Hazewinkel, H A

“…Morphologic findings in Great Dane pups fed a supplement containing three times the recommended calcium content (HC-group) and a diet which followed…”
Get more information

Progressive neuronopathy in two Cairn terrier litter mates by Zaal, M.D., van den Ingh, T.S.G.A.M., Goedegebuure, S.A., van Nes, J.J.

“…Clinical, histopathological, and EM findings are described for two Cairn terrier litter mates, an 18-month-old male and an 11-month-old female with progressive…”
Get full text

Spontaneous primary myopathies in domestic mammals: a review by Goedegebuure, S A

“…By reviewing the literature concerning primary myopathies in man and animals, a classification of spontaneous primary myopathies in domestic mammals is made…”
Get more information

Effects of divergent selection for leg weakness on angularity of joints in Duroc swine by Draper, D.D, Rothschild, M.F, Christian, L.L, Goedegebuure, S.A

“…Sixty Duroc pigs, representing offspring of three lines from the fifth generation of divergent selection for leg weakness, were examined to determine…”
Get full text