Search Results - "Godley, L"

11 INHERITED PREDISPOSITION TO MYELOID MALIGNANCIES by Godley, L

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Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes by Guidugli, L, Johnson, A K, Alkorta-Aranburu, G, Nelakuditi, V, Arndt, K, Churpek, J E, Godley, L A, Townsley, D, Young, N S, Fitzpatrick, C, del Gaudio, D, Das, S, Li, Z

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The mechanistic role of DNA methylation in myeloid leukemogenesis by Jasielec, J, Saloura, V, Godley, L A

“…The importance of epigenetic aberrations in the pathogenesis of leukemias has been revealed by recurrent gene mutations that highlight epigenetic pathways as…”
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Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins by OSTLER, K. R, DAVIS, E. M, PAYNE, S. L, GOSALIA, B. B, EXPOSITO-CESPEDES, J, LE BEAU, M. M, GODLEY, L. A

“…Cancer cells display an altered distribution of DNA methylation relative to normal cells. Certain tumor suppressor gene promoters are hypermethylated and…”
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Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4 + and CD8 + T-lymphocytes by Moshfegh, C M, Collins, C W, Gunda, V, Vasanthakumar, A, Cao, J Z, Singh, P K, Godley, L A, Case, Adam J

“…While the role of mitochondrial metabolism in controlling T-lymphocyte activation and function is becoming more clear, the specifics of how mitochondrial redox…”
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A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes by Locke, F, Agarwal, R, Kunnavakkam, R, van Besien, K, Larson, R A, Odenike, O, Godley, L A, Liu, H, Le Beau, M M, Gurbuxani, S, Thirman, M J, Sipkins, D, White, C, Artz, A, Stock, W

“…Patients with relapsed/refractory leukemias or advanced myelodysplastic syndrome (MDS) fare poorly following allogeneic hematopoietic cell transplant (HCT). We…”
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Fludarabine, Melphalan, and Alemtuzumab Conditioning in Adults With Standard-Risk Advanced Acute Myeloid Leukemia and Myelodysplastic Syndrome by VAN BESIEN, Koen, ARTZ, A, ODENIKE, O, THIRMAN, M, DAUGHERTY, C, WICKREMA, A, ZIMMERMAN, T, LARSON, R. A, STOCK, W, SMITH, S, CAO, D, RICH, S, GODLEY, L, JONES, D, DEL CERRO, P, BENNETT, D, CASEY, B

“…This prospective phase II study evaluated toxicity, relapse rate, progression-free survival, and overall survival after allogeneic transplantation and…”
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Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients by Muffly, Lori S, Kocherginsky, Masha, Stock, Wendy, Chu, Quynh, Bishop, Michael R, Godley, Lucy A, Kline, Justin, Liu, Hongtao, Odenike, Olatoyosi M, Larson, Richard A, van Besien, Koen, Artz, Andrew S

“…Allogeneic hematopoietic cell transplantation is increasingly utilized in older adults. This study prospectively evaluated the prognostic utility of geriatric…”
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Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation by POLLYEA, D. A, ARTZ, A. S, HUO, D, LARSON, R, VAN BESIEN, K, STOCK, W, DAUGHERTY, C, GODLEY, L, ODENIKE, O. M, RICH, E, SMITH, S. M, ZIMMERMAN, T, ZHANG, Y

“…We describe treatment, outcomes and prognostic factors for patients who relapse following transplantation with a reduced intensity conditioning regimen…”
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88 BONE MARROW BLAST (BMBL) RESPONSE CORRELATES WITH OVERALL SURVIVAL IN RIGOSERTIB-TREATED PATIENTS WITH HIGHER-RISK MDS AFTER FAILURE OF HYPOMETHYLATING AGENTS (HMAS): A NEW RESPONSE CRITERION? by Silverman, L.R, Fenaux, P, Al-Kali, A, Baer, M.R, Sekeres, M, Roboz, G, Gaidano, G, Scott, B, Greenberg, P, Platzbecker, U, Steensma, D.P, Kambhampati, S, Kreuzer, K.A, Godley, L, Collins, R, Atallah, E, Navada, S.C, Azarnia, N, Garcia-Manero, G

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Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation by Broccoli, D., Godley, L. A., Donehower, L. A., Varmus, H. E., De Lange, T.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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112 RANDOMIZED PHASE III STUDY OF IV RIGOSERTIB VERSUS BEST SUPPORTIVE CARE (BSC) IN PATIENTS WITH HIGHER-RISK MDS (HR-MDS) AFTER FAILURE OF HYPOMETHYLATING AGENTS (HMAS) by Garcia-Manero, G, Fenaux, P, Al-Kali, A, Baer, M.R, Sekeres, M, Roboz, G, Gaidano, G, Scott, B, Greenberg, P, Platzbecker, U, Steensma, D.P, Kambhampati, S, Kreuzer, K.A, Godley, L, Collins, R, Atallah, E, Azarnia, N, Petrone, M.E, Snyder, B.R, Maniar, M, Silverman, L.R

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Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning by KLINE, J, POLLYEA, D. A, VAN BESIEN, K, STOCK, W, ARTZ, A, RICH, E, GODLEY, L, ZIMMERMAN, T, THOMPSON, K, PURSELL, K, LARSON, R. A

“…Alemtuzumab (Campath-1H)-based conditioning regimens are effective in preventing GVHD, but are associated with very high rates of cytomegalovirus (CMV)…”
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The relationship between early renal status, and the resolution of vesico‐ureteric reflux and bladder function at 16 months by Godley, M.L., Desai, D., Yeung, C.K., Dhillon, H.K., Duffy, P.G., Ransley, P.G.

“…Objective To examine, in infants presenting with vesico‐ureteric reflux (VUR), the relationship between the presence of initial renal abnormalities with the…”
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Surgical reconstruction of cloacal malformation can alter bladder function: a comparative study with anorectal anomalies by Warne, Stephanie A, Godley, Margaret L, Wilcox, Duncan T

“…Patients with cloacal anomalies often suffer bladder dysfunction with recurrent urinary infections and incontinence. We examined the effect of surgical…”
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P741: DDX41 MUTATIONS DEFINE A UNIQUE SUBTYPE OF MYELOID NEOPLASMS by Makishima, H., Saiki, R., Nannya, Y., Korotev, S., Gurnari, C., Takeda, J., Momozawa, Y., Best, S., Krishnamurthy, P., Yoshizato, T., Atsuta, Y., Shiozawa, Y., Iijima-Yamashita, Y., Yoshida, K., Shiraishi, Y., Nagata, Y., Kakiuchi, N., Onizuka, M., Chiba, K., Tanaka, H., Kon, A., Ochi, Y., Nakagawa, M., Okuda, R., Mori, T., Itonaga, H., Miyazaki, Y., Sanada, M., Tsurumi, H., Kasahara, S., Müller-Tidow, C., Takaori-Kondo, A., Ohyashiki, K., Kiguchi, T., Matsuda, F., Jansen, J., Polprasert, C., Miyano, S., Malcovati, L., Haferlach, T., Kubo, M., Cazzola, M., Kulasekararaj, A., Godley, L., Maciejewski, J., Ogawa, S.

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Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys by Godley, L A, Kopp, J B, Eckhaus, M, Paglino, J J, Owens, J, Varmus, H E

“…Transgenic mice expressing wild-type murine p53 under the control of the mouse mammary tumor virus long terminal repeat (MMTV LTR) undergo progressive renal…”
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Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity by Godley, L, Pfeifer, J, Steinhauer, D, Ely, B, Shaw, G, Kaufmann, R, Suchanek, E, Pabo, C, Skehel, J J, Wiley, D C

“…Influenza virus hemagglutinin (HA) mediates viral entry into cells by a low pH-induced membrane fusion event in endosomes. A number of structural changes occur…”
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The validity of sacral ratios to identify sacral abnormalities by Warne, S.A., Godley, M.L., Owens, C.M., Wilcox, D.T.

“…Objective To test the repeatability and validity of a previously described sacral ratio measurement as a method for detecting sacral abnormalities, as the…”
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A preliminary study of natural‐fill radiotelemetered ovine fetal cystometry by Thiruchelvam, N., Godley, M.L., Farrugia, M.K., Cuckow, P.M.

“…OBJECTIVE To determine whether fetal cystometric studies by radiotelemetry are feasible in the fetal lamb, and potentially suitable for chronically monitoring…”
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