Search Results - "Godley, Bernard"

How Academic Medical Centers Can Navigate the Pandemic and Its Aftermath: Solutions for 3 Major Issues by Godley, Bernard F., Lawley, Thomas J., Rubenstein, Arthur, Pizzo, Philip A.

“…The COVID-19 crisis has seriously affected academic medical centers (AMCs) on multiple levels. Combined with many trends that were already under way pre…”
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Mitochondrial DNA damage and its potential role in retinal degeneration by Jarrett, Stuart G., Lin, Haijiang, Godley, Bernard F., Boulton, Michael E.

“…Mitochondria are central to retinal cell function and survival. There is increasing evidence to support an association between mitochondrial dysfunction and a…”
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The Effect of Microgravity on Ocular Structures and Visual Function: A Review by Taibbi, Giovanni, MD, Cromwell, Ronita L., PhD, Kapoor, Kapil G., MD, Godley, Bernard F., MD, PhD, Vizzeri, Gianmarco, MD

“…Abstract Ocular structural and functional changes, including optic disk edema and reduction of near visual acuity, have been recently described in some…”
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Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration by Liang, Fong-Qi, Godley, Bernard F

“…Oxidative stress is believed to contribute to the pathogenesis of many diseases, including age-related macular degeneration (AMD). Although the vision loss of…”
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Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration by Lin, Haijiang, Xu, Haifeng, Liang, Fong-Qi, Liang, Hao, Gupta, Praveena, Havey, Anna N, Boulton, Michael E, Godley, Bernard F

“…Mitochondrial DNA (mtDNA) damage may be associated with age-related diseases, such as age-related macular degeneration (AMD). The present study was designed to…”
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Ocular Outcomes Comparison Between 14- and 70-Day Head-Down-Tilt Bed Rest by Taibbi, Giovanni, Cromwell, Ronita L, Zanello, Susana B, Yarbough, Patrice O, Ploutz-Snyder, Robert J, Godley, Bernard F, Vizzeri, Gianmarco

“…To compare ocular outcomes in healthy subjects undergoing 14- and/or 70-day head-down-tilt (HDT) bed rest (BR). Participants were selected by using NASA…”
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Blue Light Induces Mitochondrial DNA Damage and Free Radical Production in Epithelial Cells by Godley, Bernard F., Shamsi, Farrukh A., Liang, Fong-Qi, Jarrett, Stuart G., Davies, Sallyanne, Boulton, Mike

“…Exposure of biological chromophores to ultraviolet radiation can lead to photochemical damage. However, the role of visible light, particularly in the blue…”
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Lipopolysaccharide Increases the Incidence of Collagen‐Induced Arthritis in Mice Through Induction of Protease HTRA‐1 Expression by Hou, Yuzhu, Lin, Haijiang, Zhu, Linnan, Liu, Zhaoting, Hu, Fanlei, Shi, Jianfeng, Yang, Tao, Shi, Xiaoyun, Zhu, Mingzhao, Godley, Bernard F., Wang, Qiang, Li, Zhanguo, Zhao, Yong

“…Objective The protease HTRA‐1 is closely associated with rheumatoid arthritis (RA). The molecular mechanisms that control HTRA‐1 expression are currently…”
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Optic disc pit maculopathy recurring in the absence of vitreous gel by Coca, Mircea N, Tofigh, Sohrab, Elkeeb, Ahmed, Godley, Bernard F

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TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization by Ameri, Hossein, Liu, Hua, Liu, Rong, Ha, Yonju, Paulucci-Holthauzen, Adriana A, Hu, Shuqun, Motamedi, Massoud, Godley, Bernard F, Tilton, Ronald G, Zhang, Wenbo

“…Retinal neovascularization (NV) is a major cause of vision loss in ischemia-induced retinopathy. Tumor necrosis factor (TNF)-like weak inducer of apoptosis…”
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Nicotine Accelerates Diabetes-Induced Retinal Changes by Boretsky, Adam, Gupta, Praveena, Tirgan, Nima, Liu, Rong, Godley, Bernard F., Zhang, Wenbo, Tilton, Ronald G., Motamedi, Massoud

“…Abstract Purpose: To investigate the effects of nicotine on retinal alterations in early-stage diabetes in an established rodent model. Materials and Methods:…”
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Ophthalmological Evaluation of Integrated Resistance and Aerobic Training During 70-Day Bed Rest by Taibbi, Giovanni, Cromwell, Ronita L, Zanello, Susana B, Yarbough, Patrice O, Ploutz-Snyder, Robert J, Godley, Bernard F, Vizzeri, Gianmarco

“…We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed…”
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Utilization of Portable Radios to Improve Ophthalmology Clinic Efficiency in an Academic Setting by Davis, Alexander S., Elkeeb, Ahmed M., Vizzeri, Gianmarco, Godley, Bernard F.

“…Improvement in clinic efficiency in the ambulatory setting is often looked at as an area for development of lean management strategies to deliver a higher…”
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Melatonin protects human retinal pigment epithelial (RPE) cells against oxidative stress by Liang, Fong-Qi, Green, Lori, Wang, Cindy, Alssadi, Rajiha, Godley, Bernard F.

“…Oxidative stress is involved in the pathogenesis of age-related macular degeneration (AMD). Administration of conventional antioxidants has been shown to slow…”
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Photokinetic Drug Delivery: Light-Enhanced Permeation in an In Vitro Eye Model by Godley, Bernard F, Kraft, Edward R, Giannos, Steven A, Zhao, Zhen-Yang, Haag, Anthony M, Wen, Julie W

“…To investigate light-enhanced molecular movement as a potential technology for drug delivery. To do this, we developed an in vitro eye model while representing…”
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Delayed suprachoroidal hemorrhage after cataract surgery by Ghorayeb, Ghassan, Khan, Adeel, Godley, Bernard F

“…To describe the clinical course of 61-year-old man who developed a delayed suprachoroidal hemorrhage 4 days after cataract surgery. This is an observational…”
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Enhanced expression of glutathione-S-transferase A1-1 protects against oxidative stress in human retinal pigment epithelial cells by Liang, Fong-Qi, Alssadi, Rajiha, Morehead, Preston, Awasthi, Yogesh C., Godley, Bernard F.

“…Glutathione-S-transferases (GSTs) play an important role in protection mechanisms against oxidative stress. We sought to determine whether over-expression of…”
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Bcl-2 Overexpression Increases Survival in Human Retinal Pigment Epithelial Cells Exposed to H2O2 by Godley, Bernard F., Jin, Gui-Fang, Guo, Yan-Shi, Hurst, John S.

“…The integrity of the retinal pigment epithelium, especially that of the macula is essential for the preservation of vision into old age. The chronic exposure…”
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Factors affecting visual outcomes after small-incision phacoemulsification in diabetic patients by Somaiya, Mamta D, Burns, Jason D, Mintz, Roni, Warren, Robert E, Uchida, Tatsuo, Godley, Bernard F

“…To examine the factors affecting visual outcome after phacoemulsification and evaluate the use of preoperative visual potential in assessing the visual…”
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Induction of Glutathione S-Transferase hGST 5.8 Is an Early Response to Oxidative Stress in RPE Cells by Singhal, Sharad S, Godley, Bernard F, Chandra, Animesh, Pandya, Utpal, Jin, Gui-Fang, Saini, Manjit K, Awasthi, Sanjay, Awasthi, Yogesh C

“…To delineate the role of the glutathione S-transferase (GST) isozyme hGST 5.8 in protection mechanisms against oxidative stress, the effect of low-level…”
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