Search Results - "Godinho‐Pereira, Joana"
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Circulating (Poly)phenol Metabolites: Neuroprotection in a 3D Cell Model of Parkinson's Disease
Published in Molecular nutrition & food research (01-11-2022)“…Scope Diets rich in (poly)phenols have been associated with positive effects on neurodegenerative disorders, such as Parkinson's disease (PD). Several…”
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Journal Article -
2
Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood-Brain Barrier Disruption
Published in International journal of molecular sciences (30-06-2021)“…Breast cancer (BC) brain metastases is a life-threatening condition to which accounts the poor understanding of BC cells' (BCCs) extravasation into the brain,…”
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Journal Article -
3
MicroRNAs and Extracellular Vesicles as Distinctive Biomarkers of Precocious and Advanced Stages of Breast Cancer Brain Metastases Development
Published in International journal of molecular sciences (14-05-2021)“…Triple negative breast cancer presents higher mortality and poorer survival rates than other breast cancer (BC) types, due to the proneness to brain metastases…”
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Journal Article -
4
Small Molecule Fisetin Modulates Alpha-Synuclein Aggregation
Published in Molecules (Basel, Switzerland) (02-06-2021)“…Phenolic compounds are thought to be important to prevent neurodegenerative diseases (ND). Parkinson's Disease (PD) is a neurodegenerative disorder known for…”
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Journal Article -
5
Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells
Published in Journal of functional foods (01-07-2018)“…[Display omitted] •Dietary intake of olive oil phenols and their metabolites reach the brain, where they are accumulated.•Hydroxytyrosol sulphate and…”
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Breast Cancer Brain Metastases: Implementation and Characterization of a Mouse Model Relying on Malignant Cells Inoculation in the Carotid Artery
Published in Cells (Basel, Switzerland) (01-08-2023)“…Breast cancer (BC) brain metastases (BCBM) is a severe condition frequently occurring in the triple-negative subtype. The study of BCBM pathogenesis and…”
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Journal Article -
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A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood-Brain Barrier
Published in Biomedicines (01-08-2022)“…Among breast cancer (BC) patients, 15-25% develop BC brain metastases (BCBM), a severe condition due to the limited therapeutic options, which points to the…”
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BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
Published in Phytochemistry reviews (01-04-2018)“…BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the…”
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Biomarcadores Genéticos e Circulantes Associados às Catecolaminas (COMT,Β2AR e TMRS) na Psoríase
Published 01-01-2012“…A Psoríase é uma doença inflamatória crónica mediada por processos imunitários, caracterizada por erupções cutâneas e que afecta cerca de 2-3% da população…”
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Dissertation -
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Inovação e Equidade no Acesso ao Medicamento
Published 01-01-2016“…Independentemente da sua condição socioeconómica, todos os países possuem políticas de saúde e medicamento que têm como objetivo promover a equidade na…”
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Dissertation