Search Results - "Godinho, M."

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system by Alterman, Julia F., Godinho, Bruno M. D. C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia

“…Sustained silencing of gene expression throughout the brain using small interfering RNAs (siRNAs) has not been achieved. Here we describe an siRNA…”
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RNAi modulation of placental sFLT1 for the treatment of preeclampsia by Turanov, Anton A, Lo, Agnes, Hassler, Matthew R, Makris, Angela, Ashar-Patel, Ami, Alterman, Julia F, Coles, Andrew H, Haraszti, Reka A, Roux, Loic, Godinho, Bruno M D C, Echeverria, Dimas, Pears, Suzanne, Iliopoulos, Jim, Shanmugalingam, Renuka, Ogle, Robert, Zsengeller, Zsuzsanna K, Hennessy, Annemarie, Karumanchi, S Ananth, Moore, Melissa J, Khvorova, Anastasia

“…Preeclampsia, a hypertension condition with no approved therapies, is treated in monkeys by gene silencing in the placenta. Preeclampsia is a placentally…”
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Performance of rotary kiln reactor for the elephant grass pyrolysis by De Conto, D., Silvestre, W.P., Baldasso, C., Godinho, M.

“…•Elephant grass was pyrolysed in a rotary kiln reactor.•The influence of temperature and rotary speed on syngas production was investigated.•Properties and…”
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Exploring the utility of Geometric Morphometrics to analyse prehistoric hand stencils by Fernández Navarro, V., Godinho, R. M., García Martínez, D., Garate Maidagan, D.

“…Hand stencils are a remarkable graphic expression in Prehistoric rock art, dating back to 42 ka BP. Although these stencils provide direct impressions of the…”
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High-Throughput and Ultrafast Liquid Chromatography by Kaplitz, Alexander S, Kresge, Glenn A, Selover, Benjamin, Horvat, Leah, Franklin, Edward G, Godinho, Justin M, Grinias, Kaitlin M, Foster, Samuel W, Davis, Joshua J, Grinias, James P

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Evaluating the Performance of Algorithms in Axillary Microwave Imaging towards Improved Breast Cancer Staging by Pato, Matilde, Eleutério, Ricardo, Conceição, Raquel C, Godinho, Daniela M

“…Breast cancer is the most common and the fifth deadliest cancer worldwide. In more advanced stages of cancer, cancer cells metastasize through lymphatic and…”
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Dielectric Characterization of Healthy Human Teeth from 0.5 to 18 GHz with an Open-Ended Coaxial Probe by Berezhanska, Mariya, Godinho, Daniela M, Maló, Paulo, Conceição, Raquel C

“…Dental caries is a major oral health issue which compromises oral health, as it is the main cause of oral pain and tooth loss. Early caries detection is…”
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BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib by Godinho, M F E, Wulfkuhle, J D, Look, M P, Sieuwerts, A M, Sleijfer, S, Foekens, J A, Petricoin, E F, Dorssers, L C J, van Agthoven, T

“…Background: High BCAR4 and ERBB2 mRNA levels in primary breast cancer associate with tamoxifen resistance and poor patient outcome. We determined whether BCAR4…”
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Diversity and bioprospecting of fungal communities associated with endemic and cold-adapted macroalgae in Antarctica by Godinho, Valéria M, Furbino, Laura E, Santiago, Iara F, Pellizzari, Franciane M, Yokoya, Nair S, Pupo, Diclá, Alves, Tânia MA, S Junior, Policarpo A, Romanha, Alvaro J, Zani, Carlos L, Cantrell, Charles L, Rosa, Carlos A, Rosa, Luiz H

“…We surveyed the distribution and diversity of fungi associated with eight macroalgae from Antarctica and their capability to produce bioactive compounds. The…”
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Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models by Conroy, Faith, Miller, Rachael, Alterman, Julia F., Hassler, Matthew R., Echeverria, Dimas, Godinho, Bruno M. D. C., Knox, Emily G., Sapp, Ellen, Sousa, Jaquelyn, Yamada, Ken, Mahmood, Farah, Boudi, Adel, Kegel-Gleason, Kimberly, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia, Pfister, Edith L.

“…Small interfering RNAs are a new class of drugs, exhibiting sequence-driven, potent, and sustained silencing of gene expression in vivo. We recently…”
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Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancer by Godinho, M F E, Sieuwerts, A M, Look, M P, Meijer, D, Foekens, J A, Dorssers, L C J, van Agthoven, T

“…Background: Breast cancer anti-oestrogen resistance 4 ( BCAR4 ) was identified in a search for genes involved in anti-oestrogen resistance in breast cancer. We…”
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A detailed non-isothermal kinetic study of elephant grass pyrolysis from different models by Collazzo, G.C., Broetto, C.C., Perondi, D., Junges, J., Dettmer, A., Dornelles Filho, A.A., Foletto, E.L., Godinho, M.

“…•The first detailed kinetic study about the elephant grass pyrolysis.•The elephant grass pyrolysis is controlled by diffusion at lower conversions.•Model-free…”
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The role of CaO in the steam gasification of plastic wastes recovered from the municipal solid waste in a fluidized bed reactor by Lazzarotto, I.P., Ferreira, S.D., Junges, J., Bassanesi, G.R., Manera, C., Perondi, D., Godinho, M.

“…•The first study addressing the role of CaO as sorbent and catalyst in the SG of MPW.•The SG of MPW with CaO in a fluidized bed reactor had high H2 and dry gas…”
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Enhanced magnetic hyperthermia of CoFe2O4 and MnFe2O4 nanoparticles by Cruz, M.M., Ferreira, L.P., Ramos, J., Mendo, S.G., Alves, A.F., Godinho, M., Carvalho, M.D.

“…CoFe2O4 and MnFe2O4 nanoparticles were obtained by hydrothermal synthesis method in aqueous and in gelatinous media, at 175 °C and 230 °C. The structural,…”
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An ant colony optimization approach to a permutational flowshop scheduling problem with outsourcing allowed by Tavares Neto, R.F., Godinho Filho, M.

“…This paper deals with the scheduling problem of minimizing the makespan in a permutational flowshop environment with the possibility of outsourcing certain…”
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Repository of MRI-derived models of the breast with single and multiple benign and malignant tumors for microwave imaging research by Pelicano, Ana C, Gonçalves, Maria C T, Castela, Tiago, Orvalho, M Lurdes, Araújo, Nuno A M, Porter, Emily, Conceição, Raquel C, Godinho, Daniela M

“…The diagnosis of breast cancer through MicroWave Imaging (MWI) technology has been extensively researched over the past few decades. However, continuous…”
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Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification by Mylopotamitaki, Dorothea, Harking, Florian S., Taurozzi, Alberto J., Fagernäs, Zandra, Godinho, Ricardo M., Smith, Geoff M., Weiss, Marcel, Schüler, Tim, McPherron, Shannon P., Meller, Harald, Cascalheira, João, Bicho, Nuno, Olsen, Jesper V., Hublin, Jean-Jacques, Welker, Frido

“…High-throughput proteomic analysis of archaeological skeletal remains provides information about past fauna community compositions and species dispersals in…”
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Conversion of MDF wastes into a char with remarkable potential to remove Food Red 17 dye from aqueous effluents by Zazycki, M.A., Perondi, D., Godinho, M., Oliveira, M.L.S., Collazzo, G.C., Dotto, G.L.

“…Medium density fiberboard (MDF) wastes were converted into an efficient char able to uptake Food Red 17 dye (FR17) from colored effluents. The yield of the…”
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Observing short-range orientational order in small-molecule liquids by Gradišek, Anton, Apih, Tomaž, Beira, Maria J., Cruz, Carlos, Fernandes, Susete N., Godinho, Helena M., Sebastião, Pedro J.

“…Local molecular ordering in liquids has attracted a lot of interest from researchers investigating crystallization, but is still poorly understood on the…”
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Liquid fibres and their networks from cellulose-based liquid crystalline solutions by Canejo, J. P., Fernandes, S. N., Godinho, M. H., Pieranski, P.

“…The production of fibres and films with enhanced mechanical properties, from liquid crystalline cellulose-based systems, has always been a challenge. Previous…”
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