Search Results - "Godin, G"
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Super-resolution Microscopy Approaches for Live Cell Imaging
Published in Biophysical journal (21-10-2014)“…By delivering optical images with spatial resolutions below the diffraction limit, several super-resolution fluorescence microscopy techniques opened new…”
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Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis
Published in Nature neuroscience (01-02-2013)“…Treatment of pain with morphine leads to paradoxical hyperalgesia. The authors provide evidence that morphine-induced hyperalgesia is a result of…”
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3
Optical manipulation of single flux quanta
Published in Nature communications (28-09-2016)“…Magnetic field can penetrate into type II superconductors in the form of Abrikosov vortices, which are magnetic flux tubes surrounded by circulating…”
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Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis
Published in PLoS computational biology (01-09-2011)“…Chloride homeostasis is a critical determinant of the strength and robustness of inhibition mediated by GABA(A) receptors (GABA(A)Rs). The impact of changes in…”
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Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization
Published in Nature communications (07-08-2020)“…GABA A /glycine-mediated neuronal inhibition critically depends on intracellular chloride (Cl − ) concentration which is mainly regulated by the K + -Cl −…”
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Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing
Published in Brain (London, England : 1878) (01-06-2019)“…Dysregulated excitability within the spinal dorsal horn is a critical mediator of chronic pain. In the rodent nerve injury model of neuropathic pain,…”
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Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain
Published in Nature communications (13-02-2020)“…Spinal disinhibition has been hypothesized to underlie pain hypersensitivity in neuropathic pain. Apparently contradictory mechanisms have been reported,…”
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Enhancing KCC2 function counteracts morphine-induced hyperalgesia
Published in Scientific reports (20-06-2017)“…Morphine-induced hyperalgesia (MIH) is a severe adverse effect accompanying repeated morphine treatment, causing a paradoxical decrease in nociceptive…”
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9
Separation of diffuse and specular components of surface reflection by use of polarization and statistical analysis of images
Published in IEEE transactions on pattern analysis and machine intelligence (01-05-2004)“…The image of an opaque object is created by observing the reflection of the light incident on its surface. The dichromatic reflection model describes the…”
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Gephyrin Clusters Are Absent from Small Diameter Primary Afferent Terminals Despite the Presence of GABAA Receptors
Published in The Journal of neuroscience (11-06-2014)“…Whereas both GABAA receptors (GABAARs) and glycine receptors (GlyRs) play a role in control of dorsal horn neuron excitability, their relative contribution to…”
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11
Stoichiometry of the human glycine receptor revealed by direct subunit counting
Published in The Journal of neuroscience (12-09-2012)“…The subunit stoichiometry of heteromeric glycine-gated channels determines fundamental properties of these key inhibitory neurotransmitter receptors; however,…”
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The relative efficacy of telephone and email reminders to elicit blood donation
Published in Vox sanguinis (01-04-2016)“…The aim of the study was to test the relative efficacy of telephone and email reminders to trigger blood donation. A sample of 3454 donors was randomized to…”
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13
Differential Expression of Acid – Sensing Ion Channels in Mouse Primary Afferents in Naïve and Injured Conditions
Published in Frontiers in cellular neuroscience (19-05-2020)“…Injury and inflammation cause tissue acidosis, which is a common feature of various painful conditions. Acid-Sensing Ion channels (ASICs) are amongst the main…”
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14
The Propagation of Tides up Rivers With Special Considerations on the Upper Saint Lawrence River
Published in Estuarine, coastal and shelf science (01-03-1999)“…The hydrodynamics of rivers affected by tides is dominated by the damping and the distortion induced by quadratic bottom friction. A compact and accurate…”
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15
Computational modeling of trans-synaptic nanocolumns, a modulator of synaptic transmission
Published in Frontiers in computational neuroscience (28-09-2022)“…Understanding synaptic transmission is of crucial importance in neuroscience. The spatial organization of receptors, vesicle release properties and…”
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Photoswitchable single-walled carbon nanotubes for super-resolution microscopy in the near-infrared
Published in Science advances (27-09-2019)“…The design of single-molecule photoswitchable emitters was the first milestone toward the advent of single-molecule localization microscopy, setting a new…”
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17
Revealing protein oligomerization and densities in situ using spatial intensity distribution analysis
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…Measuring protein interactions is key to understanding cell signaling mechanisms, but quantitative analysis of these interactions in situ has remained a major…”
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A robust and reliable methodology to perform GECI-based multi-time point neuronal calcium imaging within mixed cultures of human iPSC-derived cortical neurons
Published in Frontiers in neuroscience (25-09-2023)“…Introduction Human induced pluripotent stem cells (iPSCs), with their ability to generate human neural cells (astrocytes and neurons) from patients, hold great…”
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Associations between dietary patterns and obesity phenotypes
Published in International Journal of Obesity (01-12-2009)“…Objective: To examine whether dietary patterns are associated with obesity phenotypes. Design: Cross-sectional study. Subjects: We recruited 664 participants…”
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Spatial Intensity Distribution Analysis Reveals Abnormal Oligomerization of Proteins in Single Cells
Published in Biophysical journal (18-08-2015)“…Knowledge of membrane receptor organization is essential for understanding the initial steps in cell signaling and trafficking mechanisms, but quantitative…”
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