Search Results - "Godfraind, T"

Calcium antagonism and calcium entry blockade by Godfraind, T, Miller, R, Wibo, M

Get more information

Evidence for heterogeneity of endothelin receptor distribution in human coronary artery by Godfraind, Théophile

“…1 The receptors mediating endothelin‐evoked contraction of human coronary artery have been investigated in isolated segments of the left anterior descending…”
Get full text

Postnatal maturation of excitation-contraction coupling in rat ventricle in relation to the subcellular localization and surface density of 1,4-dihydropyridine and ryanodine receptors by WIBO, M, BRAVO, G, GODFRAIND, T

“…To better understand excitation-contraction coupling in cardiac muscle, we investigated the main Ca2+ channels involved in that process in adult and neonatal…”
Get full text

IUPHAR in Germany by Godfraind, T

Get full text

Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt‐loaded stroke‐prone hypertensive rats by Kyselovic, Jan, Krenek, Peter, Wibo, Maurice, Godfraind, Théophile

“…Calcium channel blockers (CCBs) are anti‐hypertensive drugs that are usually considered to act mainly as vasodilators. We investigated the relation between the…”
Get full text

Calcium channel blockers in cardiovascular pharmacotherapy by Godfraind, Theophile

“…This paper summarizes the pharmacological properties of calcium channel blockers (CCBs), their established therapeutic uses for cardiovascular disorders and…”
Get more information

Actions of nifedipine on calcium fluxes and contraction in isolated rat arteries by Godfraind, T

“…Experiments were performed on isolated rat aorta and superior mesenteric artery in order to study the action of nifedipine on norepinephrine and…”
Get more information

New Insights into the Therapeutic Mechanism of Action of Calcium Channel Blockers in Salt-Dependent Hypertension: Their Interaction with Endothelin Gene Expression by Godfraind, Théophile

“…It appears that the beneficial action of calcium channel blockers (CCBs) in hypertension may be related to short-term and long-term effects. This paper…”
Get full text

Comparative localization of inositol 1,4,5-trisphosphate and ryanodine receptors in intestinal smooth muscle : an analytical subfractionation study by WIBO, M, GODFRAIND, T

“…[3H]Ins(1,4,5)P3- and [3H]ryanodine-binding sites were characterized in membrane fractions from guinea-pig intestinal smooth muscle (longitudinal layer) and…”
Get full text

Importance of kinetic parameters for the tissue selectivity of calcium antagonists by Godfraind, T

Get more information

Cardioselectivity of calcium antagonists by Godfraind, T

“…Calcium antagonists comprise a diverse group of chemically unrelated agents that interact with voltage-operated calcium channels (L-type) and thereby inhibit…”
Get full text

The effect of L‐type calcium channel modulators on the mobilization of intracellular calcium stores in guinea‐pig intestinal smooth muscle by Dessy, Chantal, Godfraind, Théophile

“…1 The action of Ca2+ channel modulators has been examined on the intracellular Ca2+ signal in the longitudinal smooth muscle cells of the guinea‐pig intestine…”
Get full text

Prolonged depolarization increases the pharmacological effect of dihydropyridines and their binding affinity for calcium channels of vascular smooth muscle by Morel, N, Godfraind, T

“…Experiments were performed on isolated rat mesenteric arteries with the calcium-antagonistic dihydropyridine derivative PN 200-110 in order to examine how its…”
Get more information

Calcium exchange in vascular smooth muscle, action of noradrenaline and lanthanum by Godfraind, T

“…1. The Na, K, Ca and Mg content and the 45Ca uptake and loss were determined in rat aortae incubated in physiological solution or in solution containing LaCl3…”
Get full text

The celebration of 200 issues of TiPS by Godfraind, Théophile

Get full text

Action of the calcium channel blocker lacidipine on cardiac hypertrophy and endothelin‐1 gene expression in stroke‐prone hypertensive rats by Feron, Olivier, Salomone, Salvatore, Godfraind, Théophile

“…1 The tissue‐protective effects of calcium channel blockers in hypertension are not well dissociated from their effect on systolic blood pressure (SBP). We…”
Get full text

A comparison of the potency of selective L-calcium channel blockers in human coronary and internal mammary arteries exposed to serotonin by Godfraind, T, Dessy, C, Salomone, S

“…The actions of L-type calcium channel blockers on the contractile response to serotonin and to K(+)-depolarization have been studied in human coronary artery…”
Get more information

Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells by Eglème, C., Godfraind, T., Miller, R.C.

“…With the endothelium present, the maximum response of rat isolated aorta to clonidine was much lower than that to noradrenaline. Removal of endothelium…”
Get full text

Calcium channels in smooth muscle by Godfraind, T

Get more information

Characterization in rat aorta of the binding sites responsible for blockade of noradrenaline‐evoked calcium entry by nisoldipine by Morel, Nicole, Godfraind, Théophile

“…1 The effectiveness of the calcium antagonist, 1,4‐dihydropyridine nisoldipine, as an inhibitor of contraction and 45Ca entry evoked by noradrenaline in rat…”
Get full text