Search Results - "Goddard, K. A."

Modulation of cystic fibrosis lung disease by variants in interleukin-8 by Hillian, A D, Londono, D, Dunn, J M, Goddard, K A B, Pace, R G, Knowles, M R, Drumm, M L

“…Cystic fibrosis pulmonary disease is characterized by excessive and prolonged inflammation. CF Pulmonary disease severity exhibits considerable variation that,…”
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Health-related direct-to-consumer genetic tests: a public health assessment and analysis of practices related to Internet-based tests for risk of thrombosis by Goddard, K A B, Robitaille, J, Dowling, N F, Parrado, A R, Fishman, J, Bradley, L A, Moore, C A, Khoury, M J

“…Recent years have seen increased concern about direct-to-consumer (DTC) genetic testing (i.e., the sale and use of genetic tests without involving a health…”
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Rapid diagnosis of intrapartum group B streptococcal carriage by fluorescent in situ hybridisation by Goddard, K A, Townsend, R, Ridgway, E

“…In the UK, routine screening is not recommended as there are doubts about delivery and cost effectiveness; instead, a risk factor-based approach is advocated…”
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Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study by AIELLO BOWLES, Erin J, WELLMAN, Robert, HABEL, Laurel A, ULCICKAS YOOD, Marianne, MCCARTY, Catherine, MAGID, David J, WAGNER, Edward H, SPENCER FEIGELSON, Heather, ONITILO, Adedayo A, FREEDMAN, Andrew N, DELATE, Thomas, ALLEN, Larry A, NEKHLYUDOV, Larissa, GODDARD, Katrina A. B, DAVIS, Robert L

“…Clinical trials demonstrated that women treated for breast cancer with anthracycline or trastuzumab are at increased risk for heart failure and/or…”
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Patient actions and reactions after receiving negative results from expanded carrier screening by Kraft, S.A., Schneider, J.L., Leo, M.C., Kauffman, T.L., Davis, J.V., Porter, K.M., McMullen, C.K., Wilfond, B.S., Goddard, K.A.B.

“…With the expansion of carrier screening to general preconception and prenatal patient populations, most patients will receive negative results, which we define…”
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Confirmation of gynogenesis in Phoxinus eos-neogaeus (Pisces: Cyprinidae) by Goddard, KA, Megwinoff, O, Wessner, LL, Giaimo, F

“…We have previously reported that the all-female species Phoxinus eos-neogaeus is perpetuated at Norton Pool, New Hampshire, by clonal reproduction. Genetically…”
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HER2 evaluation and its impact on breast cancer treatment decisions by Goddard, K A B, Weinmann, S, Richert-Boe, K, Chen, C, Bulkley, J, Wax, C

“…Eighteen to twenty percent of breast cancer tumors show abnormal amplification of the Human Epidermal growth factor Receptor 2 (HER2) gene and increased…”
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Familial aggregation of Barrett’s oesophagus, oesophageal adenocarcinoma, and oesophagogastric junctional adenocarcinoma in Caucasian adults by Chak, A, Lee, T, Kinnard, M F, Brock, W, Faulx, A, Willis, J, Cooper, G S, Sivak, M V, Goddard, K A B

“…Background: Although familial clusters of Barrett’s oesophagus and oesophageal adenocarcinoma have been reported, a familial predisposition to these diseases…”
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Linkage Disequilibrium and Allele-Frequency Distributions for 114 Single-Nucleotide Polymorphisms in Five Populations by Goddard, Katrina A.B., Hopkins, Penelope J., Hall, Jeff M., Witte, John S.

“…Single-nucleotide polymorphisms (SNPs) may be extremely important for deciphering the impact of genetic variation on complex human diseases. The ultimate value…”
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Toward localization of the werner syndrome gene by linkage disequilibrium and ancestral haplotyping : Lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers by GODDARD, K. A. B, YU, C.-E, OSHIMA, J, MIKI, T, NAKURA, J, PIUSSAN, C, MARTIN, G. M, SCHELLENBERG, G. D, WIJSMAN, E. M

“…Werner syndrome (WS) is an autosomal recessive disorder characterized by premature onset of a number of age-related diseases. The gene for WS, WRN, has been…”
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Genomewide Scan for Prostate Cancer–Aggressiveness Loci by Witte, John S., Goddard, Katrina A.B., Conti, David V., Elston, Robert C., Lin, Jennifer, Suarez, Brian K., Broman, Karl W., Burmester, James K., Weber, James L., Catalona, William J.

“…The aggressiveness of prostate cancer (PCa) varies widely: some tumors progress to invasive, potentially life-threatening disease, whereas others stay latent…”
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A Genome Screen of Multiplex Sibships with Prostate Cancer by Suarez, Brian K., Lin, Jennifer, Burmester, James K., Broman, Karl W., Weber, James L., Banerjee, Tarit K., Goddard, Katrina A.B., Witte, John S., Elston, Robert C., Catalona, William J.

“…Analysis of a genome screen of 504 brothers with prostate cancer (CaP) who were from 230 multiplex sibships identified five regions with nominally positive…”
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A familial Alzheimer's disease locus on chromosome 1 by Levy-Lahad, E, Wijsman, E M, Nemens, E, Anderson, L, Goddard, K A, Weber, J L, Bird, T D, Schellenberg, G D

“…The Volga German kindreds are a group of seven related families with autosomal dominant early-onset Alzheimer's disease (AD). Linkage to known AD-related loci…”
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Allozyme analysis of clonal diversity among unisexual hybrids of the killifishes Fundulus diaphanus and F. heteroclitus by Dawley, RM, Chrzanowski, D, Phiel, KL, Beaulieu, K, Goddard, KA

“…Hybrids of the killifish species Fundulus diaphanus and F. heteroclitus are diploid unisexual gynogens producing genetically identical, all-female offspring…”
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Segregation Analysis of Phenotypic Components of Learning Disabilities. I. Nonword Memory and Digit Span by Wijsman, Ellen M., Peterson, Do, Leutenegger, Anne-Louise, Thomson, Jennifer B., Goddard, Katrina A.B., Hsu, Li, Berninger, Virginia W., Raskind, Wendy H.

“…Dyslexia is a common and complex disorder with evidence for a genetic component. Multiple loci (i.e., quantitative-trait loci [QTLs]) are likely to be…”
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Uptake, toxicity, and distribution of benzo[a]pyrene and monooxygenase induction in the topminnows Poeciliopsis monacha and Poeciliopsis lucida by Goddard, K A, Schultz, R J, Stegeman, J J

“…Poeciliopsis lucida and Poeciliopsis monacha are freshwater viviparous fishes susceptible to tumorigenesis by brief exposure to waterborne procarcinogens. The…”
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Demographic and phenotypic features of 70 families segregating Barrett’s oesophagus and oesophageal adenocarcinoma by Drovdlic, C M, Goddard, K A B, Chak, A, Brock, W, Chessler, L, King, J F, Richter, J, Falk, G W, Johnston, D K, Fisher, J L, Grady, W M, Lemeshow, S, Eng, C

“…Background: Barrett’s oesophagus (BO) also termed metaplastic columnar lined oesophageal epithelium, is believed to result from a continual reparative response…”
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Investigation of ecologically relevant wind patterns on Marion Island using Computational Fluid Dynamics and measured data by Goddard, K.A., Craig, K.J., Schoombie, J., le Roux, P.C.

“…A need was identified to have reliable quantitative wind pattern data for Marion Island (MI) in the study of terrestrial ecology (fauna and flora) on this…”
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Aclonal Reproduction by Polyploid Members of the Clonal Hybrid Species Phoxinus eos-neogaeus (Cyprinidae) by Goddard, K. A., Schultz, R. J.

“…Hybrids of the daces Phoxinus eos and P. neogaeus occur throughout the northern United States and southern Canada. Diploid hybrids and some diploid-triploid…”
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The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease by CHANG-EN YU, PAYAMI, H, ALONSO, M. E, TAYLOR, T. D, BALL, M. J, KAYE, J, MORRIS, J, CHUI, H, SADOVNICK, A. D, MARTIN, G. M, LARSON, E. B, HESTON, L. L, OLSON, J. M, BIRD, T. D, SCHELLENBERG, G. D, BOEHNKE, M, WIJSMAN, E. M, ORR, H. T, KUKULL, W. A, GODDARD, K. A. B, NEMENS, E, WHITE, J. A

“…The chromosome 19 apolipoprotein E/CI/CII gene cluster was examined for evidence of linkage to a familial Alzheimer disease (FAD) locus. The family groups…”
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