Search Results - "Goddard, G V"

Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization by Otani, S, Marshall, C J, Tate, W P, Goddard, G V, Abraham, W C

“…The involvement of new protein and messenger ribonucleic acid synthesis in long-term potentiation was studied in the anaesthetized rat dentate gyrus using…”
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Asymmetric relationships between homosynaptic long-term potentiation and heterosynaptic long-term depression by Abraham, W. C, Goddard, G. V

“…All synaptically-based neuropsychological theories of learning postulate that there are changes resulting from neural activity which are long-lasting and…”
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Reduction of long-term potentiation in the dentate gyrus of the rat following selective depletion of monoamines by Bliss, T V, Goddard, G V, Riives, M

“…1. Brief, high-frequency stimulation of the perforant path results in a long-term potentiation (l.t.p.) of the field response evoked in the dentate gyrus by…”
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Is adenosine an endogenous anticonvulsant? by Dragunow, M, Goddard, G V, Laverty, R

“…The anticonvulsant properties of adenosine were tested pharmacologically on amygdala-kindled seizure activity in rats. The adenosine analogue 2-chloroadenosine…”
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Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurones by Bilkey, D K, Goddard, G V

“…Rats under barbiturate anaesthesia were implanted with stimulating electrodes in the medial septal nucleus and the medial perforant path. A recording electrode…”
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Heterosynaptic changes accompany long-term but not short-term potentiation of the perforant path in the anaesthetized rat by Abraham, W C, Bliss, T V, Goddard, G V

“…Brief high-frequency trains of electrical stimulation delivered to the perforant path result in long-term potentiation (l.t.p.) of field potentials recorded…”
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Septohippocampal and commissural pathways antagonistically control inhibitory interneurons in the dentate gyrus by Bilkey, D K, Goddard, G V

“…Available evidence suggests that a portion of the septohippocampal pathway may form inhibitory synapses on inhibitory interneurons in the dentate gyrus. In…”
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Commissural inhibition and facilitation of granule cell discharge in fascia dentata by Douglas, R M, McNaughton, B L, Goddard, G V

“…Stimulation of the contralateral hippocampus in the hilar region had a marked effect on granule cell excitability in the fascia dentata. The primary effect was…”
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The substantia nigra is an important site for the containment of seizure generalization in the kindling model of epilepsy by Morimoto, K, Goddard, G V

“…To investigate the role of the substantia nigra (SN) in kindling, electrical stimulation of the SN was delivered at various times before or after stimulation…”
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Synaptic enhancement in fascia dentata: cooperativity among coactive afferents by McNaughton, B L, Douglas, R M, Goddard, G V

“…Evidence is presented that long-lasting enhancement of perforant path synapses following high-frequency activity is a cooperative process requiring coactivity…”
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Adenosine modulation of amygdala kindling by Dragunow, M, Goddard, G V

“…To test the hypothesis that kindling is restrained by the inhibitory neuromodulator, adenosine, the adenosine uptake blocker, papaverine, or the adenosine…”
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Proconvulsant effects of theophylline on hippocampal afterdischarges by Dragunow, M, Goddard, G V, Laverty, R

“…We tested the effects of the adenosine antagonist, theophylline, on electrically induced afterdischarges in the hippocampus of rats. Theophylline did not…”
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Kindling induced changes in EEG recorded during stimulation from the site of stimulation: collapse of GABA-mediated inhibition and onset of rhythmic synchronous burst by Morimoto, K, Goddard, G V

“…As a new approach to the functional alteration of kindled epileptogenic foci, we have demonstrated electroencephalographic (EEG) changes at the site of…”
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Deep prepyriform cortex kindling and its relation to amygdala kindling in the rat by Morimoto, K, Dragunow, M, Goddard, G V

“…Kindling of the deep prepyriform cortex (DPC), a recently identified sensitive site to chemoconvulsants, was compared to kindling of the amygdala in rats…”
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Circadian Rhythm of Synaptic Excitability in Rat and Monkey Central Nervous System by Barnes, C. A., McNaughton, B. L., Goddard, G. V., Douglas, R. M., Adamec, R.

“…Synaptic responses in hippocampal granule cells to stimulation of their afferent fibers from the entorhinal cortex fluctuate with a 24-hour period. The phase…”
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Effects of thyrotropin-releasing hormone on evoked responses and long-term potentiation in dentate gyrus of rat by Morimoto, K, Goddard, G V

“…Thyrotropin-releasing hormone (TRH), a neuropeptide with multiple neuromodulatory functions, has been receiving examination for clinical relevance in epilepsy…”
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Epileptic Focus Location: Spectral Analysis Method by Gersch, Will, Goddard, G. V.

“…A spectral analysis technique for locating the site of an epileptic focus in the cat brain with the use of multielectrode data, obtained during a generalized…”
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Effects of acute and long-term treatment with amphetamine on evoked responses and long-term potentiation in the dentate gyrus of anesthetized rats by Morimoto, K, Otani, S, Goddard, G V

“…We examined the effects of D-amphetamine (AMP) on evoked responses and long-term potentiation (LTP) in the dentate gyrus of rats in 4 different conditions:…”
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Alteration in dentate neuronal activities associated with perforant path kindling. I. Long-term potentiation of excitatory synaptic transmission by Maru, E, Goddard, G V

“…One candidate for the neuronal mechanism of kindling is the facilitation of excitatory synaptic transmission. The population EPSP component of the perforant…”
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Alteration in dentate neuronal activities associated with perforant path kindling. III. Enhancement of synaptic inhibition by Maru, E, Goddard, G V

“…Changes in the hippocampal commissural inhibition of dentate granule cell firing following perforant path kindling were examined by analysis of field…”
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