Search Results - "Godbout, K"

Recommendations from a Canadian Delphi consensus study on best practice for optimal referral and appropriate management of severe asthma by Godbout, K, Bhutani, M, Connors, L, Chan, C K N, Connors, C, Dorscheid, D, Dyck, G, Foran, V, Kaplan, A G, Reynolds, J, Waserman, S

“…In Canada, severe asthma affects an estimated 5-10% of people with asthma and is associated with frequent exacerbations, poor symptom control and significant…”
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Significance of Stenotrophomonas maltophilia When Detected in Sputum of Ambulatory Patients with COPD by Soumagne, Thibaud, Levesque, Florence, Milot, Julie, Godbout, Krystelle, Lacasse, Yves, Maltais, François

“…is an emerging Gram-negative MDR bacteria. In patients with chronic obstructive pulmonary disease (COPD), it is mostly found in those with severe exacerbation…”
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A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9 by Donoghue, Mary, Hsieh, Frank, Baronas, Elizabeth, Godbout, Kevin, Gosselin, Michael, Stagliano, Nancy, Donovan, Michael, Woolf, Betty, Robison, Keith, Jeyaseelan, Raju, Breitbart, Roger E, Acton, Susan

“…ACE2, the first known human homologue of angiotensin-converting enzyme (ACE), was identified from 5′ sequencing of a human heart failure ventricle cDNA…”
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Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells by Olazagoitia-Garmendia, Ane, Zhang, Linda, Mera, Paula, Godbout, Julie K, Sebastian-DelaCruz, Maialen, Garcia-Santisteban, Iraia, Mendoza, Luis Manuel, Huerta, Alain, Irastorza, Iñaki, Bhagat, Govind, Green, Peter H, Herrero, Laura, Serra, Dolors, Rodriguez, Jose Antonio, Verdu, Elena F, He, Chuan, Bilbao, Jose Ramon, Castellanos-Rubio, Ainara

“…Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for…”
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Anti-IL5/IL5R Treatment in COPD: Should We Target Oral Corticosteroid-Dependent Patients? by Laroche, Jérémy, Pelletier, Geneviève, Boulay, Marie-Ève, Côté, Andréanne, Godbout, Krystelle

“…Monoclonal antibodies targeting interleukin 5 (IL5) or its receptor (IL5R) are frequently used in severe asthma, in which they reduce exacerbations rate and…”
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Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase by Vickers, Chad, Hales, Paul, Kaushik, Virendar, Dick, Larry, Gavin, James, Tang, Jin, Godbout, Kevin, Parsons, Thomas, Baronas, Elizabeth, Hsieh, Frank, Acton, Susan, Patane, Michael, Nichols, Andrew, Tummino, Peter

“…Human angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a zinc metalloprotease whose closest homolog is angiotensin I-converting enzyme. To…”
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Increase in FeNO Levels Following IL5/IL5R-Targeting Therapies in Severe Asthma: A Case Series by Pelletier, Geneviève, Godbout, Krystelle, Boulay, Marie-Ève, Boulet, Louis-Philippe, Morissette, Mathieu C, Côté, Andréanne

“…Monoclonal antibodies targeting interleukin-5 (IL5) and its receptor (IL5R), used for severe asthma treatment, reduce eosinophils to almost complete depletion…”
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Construction and characterization of a radio-iodinatable mutant of recombinant human CD4 by Ferrer, Marc, Godbout, Kevin L, Sullivan, Barbara J, Austen, Douglas A, Sanderson, Christine T, Kelley, Kevin C, Osburne, Marcia S, Harrison, Stephen C, van Schravendijk, Marie R

“…Recombinant soluble human CD4 (rsCD4) has been used in iodinated form to study the interaction of CD4 with its ligands. However, the utility of [ 125 I ]-rsCD4…”
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Structural and functional characterization of an epitope in the conserved C-terminal region of HIV-1 gp120 by Ferrer, M., Sullivan, B.J., Godbout, K.L., Burke, E., Stump, H.S., Godoy, J., Golden, A., Profy, A.T., Van Schravendijk, M.R.

“…: Through an integrated study of the reactivity of a monoclonal antibody, 803‐15.6, with synthetic peptides and native recombinant HIV‐1 envelope glycoprotein…”
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