Search Results - "Godbole, Amod"

Internalization of G-protein-coupled receptors: Implication in receptor function, physiology and diseases by Calebiro, Davide, Godbole, Amod

“…G protein-coupled receptors (GPCRs) are the largest family of membrane receptors and mediate the effects of numerous hormones and neurotransmitters. The nearly…”
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Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription by Godbole, Amod, Lyga, Sandra, Lohse, Martin J., Calebiro, Davide

“…A new paradigm of G-protein-coupled receptor (GPCR) signaling at intracellular sites has recently emerged, but the underlying mechanisms and functional…”
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Publisher Correction: Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription by Godbole, Amod, Lyga, Sandra, Lohse, Martin J., Calebiro, Davide

“…The original version of this Article contained errors in the three equations reported in the Methods section entitled ‘Statistics’, as described in the…”
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AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1 by Doshi, Heena, Spengler, Katrin, Godbole, Amod, Gee, Yi Sing, Baell, Jonathan, Oakhill, Jonathan S., Henke, Andreas, Heller, Regine

“…ABSTRACT Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing mild symptoms on the mucosal entry side. However, systemic…”
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GRK specificity and Gβγ dependency determines the potential of a GPCR for arrestin-biased agonism by Matthees, Edda S. F., Filor, Jenny C., Jaiswal, Natasha, Reichel, Mona, Youssef, Noureldine, D’Uonnolo, Giulia, Szpakowska, Martyna, Drube, Julia, König, Gabriele M., Kostenis, Evi, Chevigné, Andy, Godbole, Amod, Hoffmann, Carsten

“…G protein-coupled receptors (GPCRs) are mainly regulated by GPCR kinase (GRK) phosphorylation and subsequent β-arrestin recruitment. The ubiquitously expressed…”
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To sense or not to sense—new insights from GPCR-based and arrestin-based biosensors by Haider, Raphael Silvanus, Godbole, Amod, Hoffmann, Carsten

“…Advances in resolving crystal structures of GPCRs and their binding partners as well as improvements in live-cell microscopy and the fluorescent proteins…”
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A GFP-based ratiometric sensor for cellular methionine oxidation by Kuldyushev, Nikita, Schönherr, Roland, Coburger, Ina, Ahmed, Marwa, Hussein, Rama A., Wiesel, Eric, Godbole, Amod, Pfirrmann, Thorsten, Hoshi, Toshinori, Heinemann, Stefan H.

“…Methionine oxidation is a reversible post-translational protein modification, affecting protein function, and implicated in aging and degenerative diseases…”
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Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas by Calebiro, Davide, Grassi, Elisa S, Eszlinger, Markus, Ronchi, Cristina L, Godbole, Amod, Bathon, Kerstin, Guizzardi, Fabiana, de Filippis, Tiziana, Krohn, Knut, Jaeschke, Holger, Schwarzmayr, Thomas, Bircan, Rifat, Gozu, Hulya Iliksu, Sancak, Seda, Niedziela, Marek, Strom, Tim M, Fassnacht, Martin, Persani, Luca, Paschke, Ralf

“…Autonomous thyroid adenomas (ATAs) are a frequent cause of hyperthyroidism. Mutations in the genes encoding the TSH receptor (TSHR) or the Gs protein α subunit…”
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Trafficking and function of GPCRs in the endosomal compartment by Calebiro, Davide, Godbole, Amod, Lyga, Sandra, Lohse, Martin J

“…New methods based on fluorescently labeled agonists, genetically encoded fluorescent sensors, and advanced microscopy techniques, such as fluorescence…”
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Publisher Correction: Internalized TSH receptors en route to the TGN induce local G s -protein signaling and gene transcription by Godbole, Amod, Lyga, Sandra, Lohse, Martin J, Calebiro, Davide

“…The original version of this Article contained errors in the three equations reported in the Methods section entitled 'Statistics', as described in the…”
Get full text

Internalized TSH receptors en route to the TGN induce local G s -protein signaling and gene transcription by Godbole, Amod, Lyga, Sandra, Lohse, Martin J, Calebiro, Davide

“…A new paradigm of G-protein-coupled receptor (GPCR) signaling at intracellular sites has recently emerged, but the underlying mechanisms and functional…”
Get full text