Search Results - "Godakumara, Kasun"
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Rapid increase of MFGE8 secretion from endometrial epithelial cells is an indicator of extracellular vesicle mediated embryo maternal dialogue
Published in Scientific reports (29-10-2024)“…Successful embryo implantation relies on synchronized dialog between the embryo and endometrium, and the role of extracellular vesicles (EVs) in facilitating…”
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Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability
Published in ACS omega (14-07-2020)“…Extracellular vesicles (EVs), including exosomes and microvesicles (<200 nm), play a vital role in intercellular communication and carry a net negative surface…”
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The evolving roles of extracellular vesicles in embryo-maternal communication
Published in Communications biology (21-06-2024)“…Mammalian reproduction relies on precise maternal-fetal communication, wherein immune modifications foster tolerance toward the semi-allogeneic embryo…”
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Role of extracellular vesicles in intercellular communication during reproduction
Published in Reproduction in domestic animals (01-10-2022)“…The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent…”
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Rhythm of the First Language: Dynamics of Extracellular Vesicle-Based Embryo-Maternal Communication in the Pre-Implantation Microenvironment
Published in International journal of molecular sciences (01-04-2023)“…One of the most critical steps in mammalian reproduction is implantation. Embryos with an impaired capacity for embryo-maternal crosstalk are thought to have a…”
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Extracellular vesicle research in reproductive science: Paving the way for clinical achievements
Published in Biology of reproduction (19-03-2022)“…Mammalian conception involves a multitude of reciprocal interactions via a molecular dialogue between mother and conceptus. Extracellular vesicles (EVs) are…”
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Secretory Proteomic Responses of Endometrial Epithelial Cells to Trophoblast-Derived Extracellular Vesicles
Published in International journal of molecular sciences (25-07-2023)“…Synchronized crosstalk between the embryo and endometrium during the periconception period is integral to pregnancy establishment. Increasing evidence suggests…”
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Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue
Published in Journal of molecular medicine (Berlin, Germany) (01-05-2021)“…Embryo-derived extracellular vesicles (EVs) may play a role in mediating the embryo-maternal dialogue at the oviduct, potentially carrying signals reflecting…”
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Systematic characterization of extracellular vesicles from potato (Solanum tuberosum cv. Laura) roots and peels: biophysical properties and proteomic profiling
Published in Frontiers in plant science (15-11-2024)“…Introduction Extracellular vesicles (EVs) facilitate inter and intra-species/kingdom communication through biomolecule transfer, including proteins and small…”
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Harnessing Nature's Defence: The Antimicrobial Efficacy of Pasteurised Cattle Milk-Derived Extracellular Vesicles on Staphylococcus aureus ATCC 25923
Published in International journal of molecular sciences (01-05-2024)“…Increasing antimicrobial resistance (AMR) challenges conventional antibiotics, prompting the search for alternatives. Extracellular vesicles (EVs) from…”
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Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication
Published in Reproductive biology and endocrinology (21-07-2021)“…The period of time when the embryo and the endometrium undergo significant morphological alterations to facilitate a successful implantation-known as "window…”
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Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk
Published in Cell communication and signaling (14-11-2019)“…Successful establishment of pregnancy hinges on appropriate communication between the embryo and the uterus prior to implantation, but the nature of this…”
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Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication
Published in Frontiers in molecular biosciences (16-07-2024)“…Extracellular vesicles (EVs) serve as messengers for intercellular communication, yet the precise mechanisms by which recipient cells interpret EV messages…”
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Spermatozoa, acts as an external cue and alters the cargo and production of the extracellular vesicles derived from oviductal epithelial cells in vitro
Published in Journal of cell communication and signaling (01-09-2023)“…The oviduct provides optimum physiological and biochemical milieu essential for successful fertilization, early embryo development and facilitates functional…”
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Extracellular vesicles as mediators of stress response in embryo-maternal communication
Published in Frontiers in cell and developmental biology (05-08-2024)“…The pivotal role of extracellular vesicles (EVs) in facilitating effective communication between the embryo and maternal cells during the preimplantation stage…”
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Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa
Published in Biology (Basel, Switzerland) (01-11-2021)“…While follicular fluid (FF) is known to enhance the functional properties of spermatozoa, the role of FF-derived extracellular vesicles (EVs) in this respect…”
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The Extracellular Vesicles Proteome of Endometrial Cells Simulating the Receptive Menstrual Phase Differs from That of Endometrial Cells Simulating the Non-Receptive Menstrual Phase
Published in Biomolecules (Basel, Switzerland) (01-02-2023)“…Successful embryo implantation into a receptive endometrium requires mutual endometrial-embryo communication. Recently, the function of extracellular vehicles…”
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Characterization of Extracellular Vesicles Labelled with a Lipophilic Dye Using Fluorescence Nanoparticle Tracking Analysis
Published in Membranes (Basel) (12-10-2021)“…Research on extracellular vesicles (EVs) has intensified over the past decade, including fluorescent membrane labeling of EVs. An optimal fluorescent method…”
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Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact
Published in Journal of cell communication and signaling (01-12-2020)“…The capability of spermatozoa to directly influence maternal gene expression is already established. Indeed, some of the changes induced by spermatozoa may…”
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Effect of 3D and 2D cell culture systems on trophoblast extracellular vesicle physico-chemical characteristics and potency
Published in Frontiers in cell and developmental biology (21-05-2024)“…The growing understanding of the role of extracellular vesicles (EVs) in embryo-maternal communication has sparked considerable interest in their therapeutic…”
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