Search Results - "Gockman, Kelsey"

Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized COVID-19 patients by Zuo, Yu, Warnock, Mark, Harbaugh, Alyssa, Yalavarthi, Srilakshmi, Gockman, Kelsey, Zuo, Melanie, Madison, Jacqueline A., Knight, Jason S., Kanthi, Yogendra, Lawrence, Daniel A.

“…Patients with coronavirus disease-19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions. However, bleeding complications have also been…”
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Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19 by Zuo, Yu, Estes, Shanea K, Ali, Ramadan A, Gandhi, Alex A, Yalavarthi, Srilakshmi, Shi, Hui, Sule, Gautam, Gockman, Kelsey, Madison, Jacqueline A, Zuo, Melanie, Yadav, Vinita, Wang, Jintao, Woodard, Wrenn, Lezak, Sean P, Lugogo, Njira L, Smith, Stephanie A, Morrissey, James H, Kanthi, Yogendra, Knight, Jason S

“…Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung histopathology often reveals fibrin-based blockages in the small…”
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Neutrophil extracellular traps and thrombosis in COVID-19 by Zuo, Yu, Zuo, Melanie, Yalavarthi, Srilakshmi, Gockman, Kelsey, Madison, Jacqueline A., Shi, Hui, Woodard, Wrenn, Lezak, Sean P., Lugogo, Njira L., Knight, Jason S., Kanthi, Yogendra

“…Studies of patients with COVID-19 have demonstrated markedly dysregulated coagulation and a high risk of morbid arterial and venous thrombotic events. Elevated…”
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Neutrophil calprotectin identifies severe pulmonary disease in COVID‐19 by Shi, Hui, Zuo, Yu, Yalavarthi, Srilakshmi, Gockman, Kelsey, Zuo, Melanie, Madison, Jacqueline A., Blair, Christopher, Woodward, Wrenn, Lezak, Sean P., Lugogo, Njira L., Woods, Robert J., Lood, Christian, Knight, Jason S., Kanthi, Yogendra

“…Severe cases of coronavirus disease 2019 (COVID‐19) are regularly complicated by respiratory failure. Although it has been suggested that elevated levels of…”
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Endothelial Cell–Activating Antibodies in COVID‐19 by Shi, Hui, Zuo, Yu, Navaz, Sherwin, Harbaugh, Alyssa, Hoy, Claire K., Gandhi, Alex A., Sule, Gautam, Yalavarthi, Srilakshmi, Gockman, Kelsey, Madison, Jacqueline A., Wang, Jintao, Zuo, Melanie, Shi, Yue, Maile, Michael D., Knight, Jason S., Kanthi, Yogendra

“…Objective While endothelial dysfunction has been implicated in the widespread thromboinflammatory complications of COVID‐19, the upstream mediators of…”
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Anti–Neutrophil Extracellular Trap Antibodies and Impaired Neutrophil Extracellular Trap Degradation in Antiphospholipid Syndrome by Zuo, Yu, Yalavarthi, Srilakshmi, Gockman, Kelsey, Madison, Jacqueline A., Gudjonsson, Johann E., Kahlenberg, J. Michelle, Joseph McCune, W., Bockenstedt, Paula L., Karp, David R., Knight, Jason S.

“…Objective The release of neutrophil extracellular traps (NETs) by hyperactive neutrophils has recently been recognized to play an important role in…”
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Increased Adhesive Potential of Antiphospholipid Syndrome Neutrophils Mediated by β2 Integrin Mac‐1 by Sule, Gautam, Kelley, William J., Gockman, Kelsey, Yalavarthi, Srilakshmi, Vreede, Andrew P., Banka, Alison L., Bockenstedt, Paula L., Eniola‐Adefeso, Omolola, Knight, Jason S.

“…Objective While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the…”
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Autoantibodies stabilize neutrophil extracellular traps in COVID-19 by Zuo, Yu, Yalavarthi, Srilakshmi, Navaz, Sherwin A, Hoy, Claire K, Harbaugh, Alyssa, Gockman, Kelsey, Zuo, Melanie, Madison, Jacqueline A, Shi, Hui, Kanthi, Yogendra, Knight, Jason S

“…The release of neutrophil extracellular traps (NETs) by hyperactive neutrophils is recognized to play an important role in the thromboinflammatory milieu…”
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Pediatric antiphospholipid syndrome: clinical features and therapeutic interventions in a single center retrospective case series by Madison, Jacqueline A, Gockman, Kelsey, Hoy, Claire, Tambralli, Ajay, Zuo, Yu, Knight, Jason S

“…Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory disease characterized by the presence of circulating antiphospholipid antibodies and either…”
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Antineutrophil properties of natural gingerols in models of lupus by Ali, Ramadan A, Gandhi, Alex A, Dai, Lipeng, Weiner, Julia, Estes, Shanea K, Yalavarthi, Srilakshmi, Gockman, Kelsey, Sun, Duxin, Knight, Jason S

“…Ginger is known to have antiinflammatory and antioxidative effects and has traditionally been used as an herbal supplement in the treatment of various chronic…”
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Predictors and Interrelationship of Patient‐Reported Outcomes in Antiphospholipid Syndrome: A Cross‐Sectional Study by Weiner, Julia K., Smith, Tristin, Hoy, Claire K., Sarosh, Cyrus, Madison, Jacqueline A., Ambati, Amala, Tambralli, Ajay, Peters, Noah, Packel, Corinne, Gockman, Kelsey, Zuo, Yu, Briceño, Emily M., Nagaraja, Vivek, Knight, Jason S.

“…Objective This study assessed patient‐reported outcomes (PROs) in individuals with persistently positive antiphospholipid antibodies (aPL) to better understand…”
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NETs in APS: Current Knowledge and Future Perspectives by Tambralli, Ajay, Gockman, Kelsey, Knight, Jason S.

“…Purpose of Review Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease that is primarily treated with anticoagulation. Better understanding the…”
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Neutrophil extracellular traps in COVID-19 by Zuo, Yu, Yalavarthi, Srilakshmi, Shi, Hui, Gockman, Kelsey, Zuo, Melanie, Madison, Jacqueline A, Blair, Christopher, Weber, Andrew, Barnes, Betsy J, Egeblad, Mikala, Woods, Robert J, Kanthi, Yogendra, Knight, Jason S

“…In severe cases of coronavirus disease 2019 (COVID-19), viral pneumonia progresses to respiratory failure. Neutrophil extracellular traps (NETs) are…”
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Increased adhesive potential of antiphospholipid syndrome neutrophils mediated by beta-2 integrin Mac-1 by Sule, Gautam, Kelley, William J., Gockman, Kelsey, Yalavarthi, Srilakshmi, Vreede, Andrew P., Banka, Alison L., Bockenstedt, Paula L., Eniola-Adefeso, Omolola, Knight, Jason S.

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Anti-NET antibodies and impaired NET degradation in antiphospholipid syndrome by Zuo, Yu, Yalavarthi, Srilakshmi, Gockman, Kelsey, Madison, Jacqueline A., Gudjonsson, Johann E., Kahlenberg, J. Michelle, McCune, W. Joseph, Bockenstedt, Paula L., Karp, David R., Knight, Jason S.

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Interaction of the antiphospholipid syndrome autoantigen beta-2 glycoprotein I with DNA and neutrophil extracellular traps by Kmeťová, Katarína, Lonina, Elena, Yalavarthi, Srilakshmi, Levine, Jerrold S., Hoy, Claire K., Sarosh, Cyrus, Gockman, Kelsey, Morris, Alexandra E., Tambralli, Ajay, Madison, Jacqueline A., Zuo, Yu, Subang, Rebecca, Rauch, Joyce, Knight, Jason S.

“…Beta-2 glycoprotein I (β2GPI) is a phospholipid-binding plasma protein and prominent autoantigen in antiphospholipid syndrome (APS). Here, we tested the…”
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