Search Results - "Gobl, A"

The interferon-α regulation of interferon regulatory factor 1 (IRF-1) and IRF-2 has therapeutic implications in carcinoid tumors by Zhou, Y., Wang, S., Gobl, A., Öberg, K.

“…Background: Interferon regulatory factor 1 (IRF-1) has been demonstrated to possess antiproliferative and tumor suppressor functions, on the contrary, IRF-2…”
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Transmembrane protein tyrosine phosphatase IA-2 (ICA512) is expressed in human midgut carcinoids but is not detectable in normal enterochromaffin cells by Cunningham, JL, Lopez-Egido, Janson, ET, Eriksson, B, Oberg, K, Gobl, AE

“…A potential upregulation of receptor type protein tyrosine phosphatase IA-2 (ICA512) expression was detected by differential display and investigated in midgut…”
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Enhanced expression of transforming growth factor-beta s and transforming growth factor-beta type II receptor in the synovial tissues of patients with rheumatoid arthritis by Taketazu, F, Kato, M, Gobl, A, Ichijo, H, ten Dijke, P, Itoh, J, Kyogoku, M, Rönnelid, J, Miyazono, K, Heldin, C H

“…A growing body of evidences suggests that transforming growth factor-beta (TGF-beta) is produced in the synovial fluid of patients with rheumatoid arthritis…”
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Inhibition of CDK2, CDK4 and cyclin E and increased expression of p27Kip1 during treatment with interferon-alpha in carcinoid tumor cells by Zhou, Y, Wang, S, Gobl, A, Oberg, K

“…IFN-alpha has presented antitumor effect in about 50% of carcinoid tumor patients, though the antitumor mechanism of IFN-alpha is still to be elucidated. In…”
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Different induction patterns of mRNA for IFN-alpha and -beta in human mononuclear leukocytes after in vitro stimulation with herpes simplex virus-infected fibroblasts and Sendai virus by Gobl, AE, Funa, K, Alm, GV

“…Human peripheral blood mononuclear leukocytes (PBL) were stimulated in vitro by HSV type 1-infected glutaraldehyde-fixed fibroblasts, or Sendai virus (SV). The…”
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Human papillomavirus testing versus cytology in primary cervical cancer screening: End‐of‐study and extended follow‐up results from the Canadian cervical cancer screening trial by Isidean, Sandra D., Mayrand, Marie‐Hélène, Ramanakumar, Agnihotram V., Gilbert, Laura, Reid, Stephanie L., Rodrigues, Isabel, Ferenczy, Alex, Ratnam, Sam, Coutlée, François, Franco, Eduardo L.

“…The Canadian Cervical Cancer Screening Trial was a randomized controlled trial comparing the performance of human papillomavirus (HPV) testing and Papanicolaou…”
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Expression of a mast cell tryptase in the human monocytic cell lines U-937 and Mono Mac 6 by Huang, R, Abrink, M, Gobl, A E, Nilsson, G, Aveskogh, M, Larsson, L G, Nilsson, K, Hellman, L

“…Expression of a mast cell tryptase mRNA was detected in two human monocytic cell lines, the U-937 and the Mono Mac 6, and in normal human peripheral blood (PB)…”
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Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage by Abrink, M, Gobl, A E, Huang, R, Nilsson, K, Hellman, L

“…Three human monocytic cell lines, U-937, THP-1 and Mono Mac 6 have, because of their morphology and staining properties, been classed as cell lines frozen in a…”
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Interleukin-4 down-regulates Sendai virus-induced production of interferon-alpha and -beta in human peripheral blood monocytes in vitro by Gobl, A E, Alm, G V

“…Recombinant interleukin-4 (rIL-4) caused a 65-70% reduction of the interferon-alpha (IFN-alpha) and -beta production induced by Sendai virus (SV) in human…”
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Competitive PCR demonstrates that 9-cis retinoic acid induces cellular retinoic acid-binding protein-II more efficiently than all-trans retinoic acid in human osteosarcoma cells by Melhus, H, Gobl, A, Ljunghall, S

“…Cellular retinoic acid-binding proteins (CRABPs) are thought to play a key role in the regulation of the levels of retinoic acid (RA) available to interact…”
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Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism by Gobl, Anders E., Berg, Mikael, Lopez-Egido, Juan R., Öberg, Kjell, Skogseid, Britt, Westin, Gunnar

“…Recently the multiple endocrine neoplasia type 1 ( MEN-1) tumor suppressor gene was cloned. MEN-1 encodes a nuclear protein, called menin, of hitherto unknown…”
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Characterization of the blood mononuclear leucocytes producing alpha interferon after stimulation with herpes simplex virus in vitro, by means of combined immunohistochemical staining and in situ RNA-RNA hybridization by Sandberg, K, Gobl, A E, Funa, K, Alm, G V

“…A procedure is described for combined immunohistochemical staining and in situ RNA-RNA hybridization of human peripheral blood mononuclear leucocytes (PBMC)…”
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Interferon-alpha but not -beta genes require de novo protein synthesis for efficient expression in human monocytes by Gobl, A E, Cederblad, B, Sandberg, K, Alm, G V

“…Monocytes produce interferon-alpha (IFN)-alpha) and -beta when human peripheral blood mononuclear cells (PBMCs) are stimulated in vitro by Sendai virus (SV)…”
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Development of polyclonal antibodies and evaluation of a sensitive radioimmunoassay for detection and measurement of synaptophysin by Stridsberg, M, Lundqvist, G, Engström, U, Wilander, E, Su, H, Gobl, A, Oberg, K

“…Polyclonal antibodies directed towards synaptophysin were raised against a synthesised peptide corresponding to amino acids 246 to 260 of the human…”
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Candidate genes for multiple endocrine neoplasia type 1 by Lagercrantz, J, Larsson, C, Grimmond, S, Skogseid, B, Gobl, A, Friedman, E, Carson, E, Phelan, C, Oberg, K, Nordenskjöld, M

“…The aim of this study was to isolate and characterize candidates for the multiple endocrine neoplasia type 1 (MEN1) gene. The development of tumours related to…”
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Induction of MxA mRNA in patients with neuroendocrine tumors after interferon treatment. Lack of correlation with antitumor response by Imam, H, Janson, E T, Gobl, A, Alm, G, Oberg, K

“…We have investigated the possibility of using induction of MxA mRNA in patients with neuroendocrine tumors undergoing interferon-alpha(IFN-alpha) treatment as…”
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Phorbol ester-mediated inhibition of IFN-alpha/beta gene transcription in blood mononuclear leukocytes by Sandberg, K, Eloranta, ML, Gobl, AE, Alm, GV

“…The phorbol ester PMA efficiently inhibits the in vitro IFN-alpha and -beta responses in human blood monocytes induced by Sendai virus and in natural…”
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Molecular cloning and characterization of a cDNA encoding the rat interleukin-8 receptor by Gobl, Anders E, Huang, Mallen R, Wang, Shu, Zhou, Yinghua, Öberg, Kjell

“…In this study we present the cloning, characterization and expression analysis of a cDNA encoding a rat interleukin-8 receptor (rIL-8R). A 1324 bp cDNA…”
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Transfection of the Multiple Endocrine Neoplasia Type 1 Gene to a Human Endocrine Pancreatic Tumor Cell Line Inhibits Cell Growth and Affects Expression of JunD, δ-Like Protein 1/Preadipocyte Factor-1, Proliferating Cell Nuclear Antigen, and QM/Jif-1 by Stålberg, Peter, Grimfjärd, Per, Santesson, Mårten, Zhou, Yinghua, Lindberg, Daniel, Gobl, Anders, Öberg, Kjell, Westin, Gunnar, Rastad, Jonas, Wang, Shu, Skogseid, Britt

“…In the absence of metastases or overgrowth to adjacent organs, the lack of reliable markers for malignancy is a well-recognized problem for clinicians managing…”
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The induction of interferon-alpha and interferon-beta mRNA in human natural interferon-producing blood leukocytes requires de novo protein synthesis by Cederblad, B, Gobl, A E, Alm, G V

“…The induction of interferon-alpha (IFN-alpha) and IFN-beta mRNA in natural IFN producing (NIP) cells in cultures of human peripheral blood mononuclear cells…”
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