Search Results - "Gobinet, Cyril"
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Towards normalization selection of Raman data in the context of protein glycation: application of validity indices to PCA processed spectra
Published in Analyst (London) (21-04-2020)“…Raman spectroscopy is a candidate technique for diagnosis applications in medicine due to its high molecular specificity. Optimizing the pre-treatment applied…”
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2
Analysis of Hepatic Fibrosis Characteristics in Cirrhotic Patients with and without Hepatocellular Carcinoma by FTIR Spectral Imaging
Published in Molecules (Basel, Switzerland) (07-09-2020)“…The evolution of cirrhosis is marked by quantitative and qualitative modifications of the fibrosis tissue and an increasing risk of complications such as…”
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3
Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide
Published in Scientific reports (09-08-2017)“…Lumican is a small leucine-rich proteoglycan (SLRP) being known as a key regulator of collagen fibrillogenesis. However, little attention has been given so far…”
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4
Characterization of cancer-associated adipocytes by Raman spectroscopy and trajectory inference
Published in PhotoniX (01-12-2024)“…Cancer-associated adipocytes (CAAs) have emerged as pivotal players in various cancers, particularly in such as breast cancer, significantly influencing their…”
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Demonstration of the Protein Involvement in Cell Electropermeabilization using Confocal Raman Microspectroscopy
Published in Scientific reports (19-01-2017)“…Confocal Raman microspectroscopy was used to study the interaction between pulsed electric fields and live cells from a molecular point of view in a…”
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6
Raman spectral imaging of single cancer cells: probing the impact of sample fixation methods
Published in Analytical and bioanalytical chemistry (01-08-2010)“…Raman spectroscopy has proven its potential for the analysis of cell constituents and processes. However, sample preparation methods compatible with clinical…”
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7
IR spectral imaging of secreted mucus: a promising new tool for the histopathological recognition of human colonic adenocarcinomas
Published in Histopathology (01-06-2010)“…Travo A, Piot O, Wolthuis R, Gobinet C, Manfait M, Bara J, Forgue‐Lafitte M‐E & Jeannesson P (2010) Histopathology 56, 921–931 IR spectral imaging of secreted…”
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8
Unsupervised Feature Selection by a Genetic Algorithm for Mid-Infrared Spectral Data
Published in Analytical chemistry (Washington) (22-11-2022)“…Dimensional reduction of highly multidimensional datasets such as those acquired by Fourier transform infrared spectroscopy (FTIR) is a critical step in the…”
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9
Trajectory Inference for Unraveling Dynamic Biological Processes from Raman Spectral Data
Published in Analytical chemistry (Washington) (07-03-2023)“…Cell heterogeneity is a crucial parameter for understanding the complexity of numerous biomedical issues. Trajectory inference-based approaches are recent…”
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10
Shedding light on confounding factors likely to affect salivary infrared biosignatures
Published in Analytical and bioanalytical chemistry (01-04-2019)“…Total human saliva is a biofluid which can be considered as a “mirror” reflecting the state of the body’s health. The “spectral mid-infrared fingerprint”…”
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11
Renal Graft Fibrosis and Inflammation Quantification by an Automated Fourier-Transform Infrared Imaging Technique
Published in Journal of the American Society of Nephrology (01-08-2016)“…Renal interstitial fibrosis and interstitial active inflammation are the main histologic features of renal allograft biopsy specimens. Fibrosis is currently…”
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12
Longitudinal Study of Cirrhosis Development in STAM and carbon tetrachloride Mouse Models Using Fourier Transform Infrared Spectral Imaging
Published in Laboratory investigation (01-10-2023)“…Animal models of cirrhosis are of great interest to investigate the pathological process leading to the final stage of cirrhosis. The aim of this study was to…”
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13
Automatic Identification of Paraffin Pixels on FTIR Images Acquired on FFPE Human Samples
Published in Analytical chemistry (Washington) (02-03-2021)“…The transfer of mid-infrared spectral histopathology to the clinic will be possible provided that its application in clinical practice is simple. Rapid…”
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14
Infrared spectral histopathology for cancer diagnosis: a novel approach for automated pattern recognition of colon adenocarcinoma
Published in Analyst (London) (21-08-2014)“…Histopathology remains the gold standard method for colon cancer diagnosis. Novel complementary approaches for molecular level diagnosis of the disease are…”
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15
Rapid screening of classic galactosemia patients: a proof-of-concept study using high-throughput FTIR analysis of plasma
Published in Analyst (London) (07-04-2015)“…Classic galactosemia is an autosomal recessive metabolic disease involving the galactose pathway, caused by the deficiency of galactose-1-phosphate…”
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16
Comprehensive Characterization of the Interaction between Pulsed Electric Fields and Live Cells by Confocal Raman Microspectroscopy
Published in Analytical chemistry (Washington) (17-10-2017)“…This study reports a comprehensive analysis of the effect of 100 μs electric pulses on the biochemical composition of live cells using a label-free approach,…”
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17
Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin
Published in Analyst (London) (21-08-2012)“…The present paper provides a spectral comparison between abdominal human skin (Transkin) and pig ear skin using confocal Raman microspectroscopy at 660 nm. Pig…”
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New insights into hidradenitis suppurativa diagnosis via salivary infrared biosignatures: A pilot study
Published in Journal of biophotonics (01-03-2021)“…Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease which can lead to a prolonged physical disability. HS diagnosis is exclusively clinical…”
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19
Longitudinal study of cirrhosis development in STAM™ and CCl 4 mouse models using FTIR spectral imaging
Published in Laboratory investigation (04-08-2023)“…Animal models of cirrhosis are of great interest to investigate the pathological process leading to the final stage of cirrhosis. The aim of this study was to…”
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20
Raman-based detection of hydroxyethyl starch in kidney allograft biopsies as a potential marker of allograft quality in kidney transplant recipients
Published in Scientific reports (09-09-2016)“…In brain-dead donor resuscitation, hydroxyethyl starch (HES) use has been associated with presence of osmotic-nephrosis-like lesions in kidney transplant…”
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