Search Results - "Goździk, Aneta"
-
1
Effect of structural modification at the 4, 3′, and 2′ positions of doxorubicin on topoisomerase II poisoning, apoptosis, and cytotoxicity in human melanoma cells
Published in Archivum Immunologiae et Therapiae Experimentalis (01-06-2007)“…Introduction: The mechanism of the cytotoxicity of anthracyclines is pleiotropic and its significance in cell growth inhibition seems to be highly specific and…”
Get full text
Journal Article -
2
Relationship between Topoisomerase II-DNA Cleavable Complexes, Apoptosis and Cytotoxic Activity of Anthracyclines in Human Cervix Carcinoma Cells
Published in Anticancer research (01-05-2005)“…The use of anthracyclines as antitumor drugs dates back to the 1970s, but the mechanism of the cytotoxicity of these compounds has long been a matter of…”
Get full text
Journal Article -
3
Inhibition of poly(ADP-ribose)polymerase does not affect the recombination events in CHO xrs6 and wild type cells
Published in Radiation and environmental biophysics (01-11-2006)“…Activation of poly (ADP-ribose) polymerase -1 (PARP-1) is an early DNA damage response event that, together with phosphorylation of p53, prompts various…”
Get full text
Journal Article -
4
Topoisomerase II alpha expression and cytotoxicity of anthracyclines in human neoplastic cells
Published in Acta Poloniae pharmaceutica (01-01-2006)“…Topoisomerase II is ATP dependent enzyme that catalyzes DNA strand passage, the pivotal process in replication, transcription, recombination etc. As part of…”
Get full text
Journal Article